Tyk2-IN-8

Modify Date: 2024-01-05 16:02:35

Tyk2-IN-8 Structure
Tyk2-IN-8 structure
Common Name Tyk2-IN-8
CAS Number 2704587-24-4 Molecular Weight 425.46
Density N/A Boiling Point N/A
Molecular Formula C20H19D3N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tyk2-IN-8


Tyk2-IN-8 (Compound 3) is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].

 Names

Name Tyk2-IN-8

 Tyk2-IN-8 Biological Activity

Description Tyk2-IN-8 (Compound 3) is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].
Related Catalog
References

[1]. Xiangyang Chen, et al. Heterocyclic compounds for inhibiting tyk2 activities. WO2021180072A1.

 Chemical & Physical Properties

Molecular Formula C20H19D3N8O3
Molecular Weight 425.46