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琥珀磺胺噻唑

琥珀磺胺噻唑用途

Succinylsulfathiazole为磺胺类化合物,是超长效药物。
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琥珀磺胺噻唑名称

[ CAS 号 ]:
116-43-8

[ 中文名 ]:
琥珀酰磺胺噻唑

[ 英文名 ]:
succinylsulfathiazole

[中文别名 ]:

[英文别名 ]:

琥珀磺胺噻唑生物活性

[ 描述 ]:

Succinylsulfathiazole为磺胺类化合物,是超长效药物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌
研究领域 >> 感染

[相关活性小分子]

嘌呤霉素二盐酸盐 | G-418 硫酸盐 | 衣霉素 | 潮霉素B | 盐霉素 | 阿维巴坦钠 | 硫酸新霉素 | 法硼巴坦 | 甲氧西林钠 | 利福平 | 甲硝唑 | 羧苄青霉素钠 | 头孢他啶 | 盐酸依拉环素 | 头孢噻肟钠

琥珀磺胺噻唑物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 熔点 ]:
187 - 193ºC

[ 分子式 ]:
C13H13N3O5S2

[ 分子量 ]:
355.389

[ 精确质量 ]:
355.029663

[ PSA ]:
162.08000

[ LogP ]:
0.68

[ 折射率 ]:
1.679

[ 储存条件 ]:
室温，干燥

琥珀磺胺噻唑MSDS

详细MSDS(安全技术说明书)

琥珀磺胺噻唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM4767000
CHEMICAL NAME :
Succinanilic acid, 4'-(2-thiazolylsulfamoyl)-
CAS REGISTRY NUMBER :
116-43-8
BEILSTEIN REFERENCE NO. :
0349989
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H13-N3-O5-S2
MOLECULAR WEIGHT :
355.41
WISWESSER LINE NOTATION :
T5N CSJ BMSWR DMV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,231,1942
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 7,151,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81640 No. of Facilities: 58 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 230 (estimated)
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琥珀磺胺噻唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R42/43

[ 安全声明 (欧洲) ]:
S22-S36/37-S45

[ 危险品运输编码 ]:
3249

[ WGK德国 ]:
3

[ RTECS号 ]:
WM4767000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2935009090

琥珀磺胺噻唑合成路线

详细合成路线

琥珀磺胺噻唑上下游产品

琥珀磺胺噻唑上游产品

琥珀磺胺噻唑下游产品

琥珀磺胺噻唑制备

由对琥珀酰氨基苯磺酰氯与乙氨基噻唑为原料制得。

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琥珀磺胺噻唑海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

琥珀磺胺噻唑文献

Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.

Toxicol. Lett. 215(3) , 214-8, (2012)

In most mammalian species, arsenic biotransformation occurs primarily by biomethylation and reduction reactions, with dimethylarsinic acid being the predominant metabolite excreted in the urine. Methy...

Prediction of drug intestinal absorption by new linear and non-linear QSPR.

Eur. J. Med. Chem. 46 , 218-28, (2011)

In order to minimize the high attrition rate that usually characterizes drug research and development projects, current medicinal chemists aim to characterize both pharmacological and ADME profiles at...

Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.

J. Neurosci. 28 , 7219-7230, (2008)

Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like stroke and dementia. Moreover, folate deficie...


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推荐生产厂家/供应商：

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥918.0/1g

联系人：刘佳

产品详情：丁二酰磺胺噻唑

公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥323.0/25g ￥142.0/5g ￥59.0/1g

联系人：夏言

产品详情：[Perfemiker]丁二酰磺胺噻唑,≥99 %

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥1051.9/100g ￥308.9/1ml ￥2152.9/250g ￥288.9/25g

联系人：阿拉丁李高志

产品详情：琥珀酰磺胺噻唑

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