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芍药苷

芍药苷用途

Paeoniflorin由白芍根提取的天然产物。

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芍药苷名称

[ CAS 号 ]:
23180-57-6

[ 中文名 ]:
芍药苷

[ 英文名 ]:
Paeoniflorin

[中文别名 ]:

[英文别名 ]:

paeoniflorine
Paeony root
Delmacinone
Paeonia moutan
peoniflorin
MFCD00869331
Paeonia lactiflora P,E,
Paeoniflorm
EINECS 245-476-2
PAEONIFLORIN(P)

芍药苷生物活性

[ 描述 ]:

Paeoniflorin由白芍根提取的天然产物。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> HIF/HIF脯氨酰-羟化酶

研究领域 >> 神经疾病

天然产物 >> 萜类化合物和糖苷

[参考文献]

[1]. Cao, B.Y., et al., Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway. J Ethnopharmacol, 2010. 131(1): p. 122-9.

[2]. Takeuchi, T., et al., Effect of paeoniflorin, glycyrrhizin and glycyrrhetic acid on ovarian androgen production. Am J Chin Med, 1991. 19(1): p. 73-8.

[3]. Yan, D., et al., Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones, 2004. 9(4): p. 378-89.

[相关活性小分子]

芍药苷物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
690.2±55.0 °C at 760 mmHg

[ 分子式 ]:
C₂₃H₂₈O₁₁

[ 分子量 ]:
480.462

[ 闪点 ]:
238.4±25.0 °C

[ 精确质量 ]:
480.163147

[ PSA ]:
164.37000

[ LogP ]:
-0.42

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±2.3 mmHg at 25°C

[ 折射率 ]:
1.683

[ 储存条件 ]:
room temp

芍药苷MSDS

详细MSDS(安全技术说明书)

芍药苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RT1200000

CHEMICAL NAME :: Paeoniflorin

CAS REGISTRY NUMBER :: 23180-57-6

LAST UPDATED :: 199112

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H28-O11

MOLECULAR WEIGHT :: 480.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3530 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,899,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9530 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity)

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,899,1969

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芍药苷安全信息

[ 危害码 (欧洲) ]:
Xn,N,T,F

[ 风险声明 (欧洲) ]:
R22:Harmful if swallowed. R50:Very Toxic to aquatic organisms. R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed . R23/24/25:Toxic by inhalation, in contact with skin and if swallowed

[ 安全声明 (欧洲) ]:
S61-S45-S36/37

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
XZ3015000

[ 海关编码 ]:
2932999099

芍药苷合成路线

详细合成路线

芍药苷上下游产品

芍药苷上游产品

芍药苷下游产品

芍药苷制备

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芍药苷海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

芍药苷文献

Chemical profiling and quantification of Gua-Lou-Gui-Zhi decoction by high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and ultra-performance liquid chromatography/triple quadrupole mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 986-987 , 69-84, (2015)

Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study...

[Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].

Zhongguo Zhong Yao Za Zhi 36(11) , 1508-11, (2011)

To explore the effects of Baixiangdan capsule (BXD), a Chinese medicinal formula, on the premenstrual syndrome (PMS) rats with Liver-qi invasion and the possible underlying micro-mechanisms.Wistar rat...

Detection of paeoniflorin and albiflorin by immunostaining technique using anti-paeoniflorin monoclonal antibody.

Phytochem. Anal. 24(2) , 124-8, (2013)

Paeoniae radix is one of the most important crude drugs used in Kampo medicines (KMs). A part of its pharmaceutical properties is due to the presence of paeoniflorin (PF) and albiflorin (AF).For the s...

更多文献

芍药苷

芍药苷用途

芍药苷名称

芍药苷生物活性

芍药苷物理化学性质

芍药苷MSDS

详细MSDS(安全技术说明书)

芍药苷毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

芍药苷安全信息

芍药苷合成路线

详细合成路线

芍药苷上下游产品

芍药苷上游产品

芍药苷下游产品

芍药苷制备

芍药苷海关

芍药苷文献

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