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拉沙洛西

拉沙洛西用途

Lasalocid是一种抗菌剂和抗球虫药, 用在饲料添加剂中。

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拉沙洛西名称

[ CAS 号 ]:
25999-31-9

[ 中文名 ]:
那塞罗

[ 英文名 ]:
Lasalocid

[中文别名 ]:

[英文别名 ]:

lasalocid
Antibiotic X-537A
lasalic acid
Bovatec
Ionophore X-4537A
lasalocid acid

拉沙洛西生物活性

[ 描述 ]:

Lasalocid是一种抗菌剂和抗球虫药, 用在饲料添加剂中。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

天然产物 >> 其他

[相关活性小分子]

拉沙洛西物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
735.7±60.0 °C at 760 mmHg

[ 分子式 ]:
C₃₄H₅₄O₈

[ 分子量 ]:
590.788

[ 闪点 ]:
224.8±26.4 °C

[ 精确质量 ]:
590.381897

[ PSA ]:
133.52000

[ LogP ]:
6.55

[ 蒸汽压 ]:
0.0±2.5 mmHg at 25°C

[ 折射率 ]:
1.529

[ 储存条件 ]:
-20°C

拉沙洛西毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP4000000

CHEMICAL NAME :: 2,3-Cresotic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl -2H-pyran-2-yl) tetrahydro-3-methyl-2-furyl)-4-hydroxy-3,5-dimethyl-6 -oxononyl)-, (-)-

CAS REGISTRY NUMBER :: 25999-31-9

LAST UPDATED :: 199706

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C34-H54-O8

MOLECULAR WEIGHT :: 590.88

WISWESSER LINE NOTATION :: T6OTJ B1 CQ C2 F- ET5OTJ BY2&VY1&YQY1&2R CQ D1 BVQ& C1 E2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 122 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 146 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,502,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,809,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 72 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 26,322,1984

拉沙洛西

拉沙洛西用途

拉沙洛西名称

拉沙洛西生物活性

拉沙洛西物理化学性质

拉沙洛西毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

拉沙洛西合成路线

详细合成路线

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拉沙洛西下游产品

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