SRI 62320

Modify Date: 2025-08-25 18:03:33

SRI 62320 structure	Common Name	SRI 62320
	CAS Number	94061-80-0	Molecular Weight	433.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₅FNNaO₄	Melting Point	N/A
	MSDS	Chinese	Flash Point	N/A

Use of SRI 62320

(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].

Name	sodium,(E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoate
Synonym	More Synonyms

Description	(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Signaling Pathways >> Autophagy >> Autophagy
References	[1]. Araújo FA, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [2]. Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)

Signaling Pathways >> Autophagy >> Autophagy

References

[1]. Araújo FA, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.

[2]. Makabe S, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.

Molecular Formula	C₂₄H₂₅FNNaO₄
Molecular Weight	433.45
Exact Mass	433.16700
PSA	85.52000
LogP	3.29340

Precursor 7
CAS#:1353637-16-7 E-(7-[3-(4-fluo... CAS#:786710-21-2 Fluvastatin Met... CAS#:194934-96-8 2-PHENYLETHYLIS... CAS#:93957-50-7 1-Isopropyl-2-a...
CAS#:194934-95-7 tert-Butyl (E)-... CAS#:124655-09-0 (4R-Cis)-6-Hydr... CAS#:1353637-28-1 2-[(4R,6S)-6-me...
DownStream 1
CAS#:93957-54-1 Fluvastatin

(3R,5S)-7-(3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoic acid monosodium salt

Canef

FLUVASTATIN SODIUM

(+)-(3R,5S)-fluvastatin sodium

(3R,5S,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid sodium salt

XU-62-320

Lescol

fluindostatin

(E)-(3R,5S)-(+)-7-[3-(4-fluoro-phenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-hept-6-enoic acid sodium salt

erythro-(E)-3R,5S-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid,sodium salt

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China
Product Name: Palmitic acid
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: SRI 62320
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Purity: 98.0%
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SRI 62320

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SRI 62320 Biological Activity

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.