PROTAC Linker 15 structure
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Common Name | PROTAC Linker 15 | ||
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CAS Number | 101187-40-0 | Molecular Weight | 292.37200 | |
Density | 1.05 | Boiling Point | N/A | |
Molecular Formula | C13H28N2O5 | Melting Point | N/A | |
MSDS | Chinese | Flash Point | N/A |
Use of PROTAC Linker 15PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Name | tert-butyl N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]carbamate |
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Synonym | More Synonyms |
Description | PROTAC Linker 15 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 15 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
References |
Density | 1.05 |
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Molecular Formula | C13H28N2O5 |
Molecular Weight | 292.37200 |
Exact Mass | 292.20000 |
PSA | 92.04000 |
LogP | 1.61080 |
Hazard Codes | Xi |
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HS Code | 2924199090 |
~97% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Tetrahedron, , vol. 68, # 52 p. 10818 - 10826 |
~32% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: WO2005/30258 A2, ; Page/Page column 115 ; WO 2005/030258 A2 |
~78% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
~26% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Journal of Organic Chemistry, , vol. 66, # 11 p. 3709 - 3716 |
~98% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Tetrahedron Letters, , vol. 39, # 48 p. 8799 - 8802 |
~% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
~% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
~% PROTAC Linker 15 CAS#:101187-40-0 |
Literature: Journal of the American Chemical Society, , vol. 134, # 1 p. 83 - 86 |
Precursor 9 | |
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DownStream 1 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
t-Boc-N-Amido-PEG3-Amine |
13-AMINO-5,8,11-TRIOXA-2-AZATRIDECANOIC ACID 1,1-DIMETHYLETHYL ESTER |
1-Boc-amine-11-amino-3,6,9-trioxaundecane |