Topoisomerase II inhibitor 9
Modify Date: 2024-01-18 09:32:35
Topoisomerase II inhibitor 9 structure
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Common Name | Topoisomerase II inhibitor 9 | ||
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| CAS Number | 2413901-61-6 | Molecular Weight | 491.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H17N7O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Topoisomerase II inhibitor 9Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells[1]. |
| Name | Topoisomerase II inhibitor 9 |
|---|
| Description | Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells[1]. |
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| Related Catalog | |
| Target |
Topoisomerase II:0.97 μM (IC50) |
| In Vitro | Topoisomerase II inhibitor 9 (Compound 19b) shows antiproliferative activity with IC50 values of 0.50 ± 0.1, 0.75 ± 0.1 and 2.91 ± 0.1 μM against Hep G‐2, Hep‐2 and Caco‐2 cells, respectively[1]. |
| References |
| Molecular Formula | C22H17N7O3S2 |
|---|---|
| Molecular Weight | 491.55 |