Topoisomerase II inhibitor 11 structure
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Common Name | Topoisomerase II inhibitor 11 | ||
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CAS Number | 2476559-00-7 | Molecular Weight | 588.34 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C27H21BrCl2N2O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Topoisomerase II inhibitor 11Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC50 of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC50 of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity[1]. |
Name | Topoisomerase II inhibitor 11 |
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Description | Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC50 of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC50 of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity[1]. |
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Related Catalog | |
Target |
Topoisomerase II:2.89 μM (IC50) |
References |
Molecular Formula | C27H21BrCl2N2O2S |
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Molecular Weight | 588.34 |