e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Synthesis and antifungal activity of a series of novel 1, 2-disubstituted propenones

M Ogata, H Matsumoto, S Kida, S Shimizu…

Index: Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502

Full Text: HTML

Citation Number: 43

Abstract

To find an antifungal agent other than those of the imidazole and triazole series, a new class of 1, 2-disubstituted propenones I and I1 was prepared and tested for antifungal activity. Comparison of the structure-activity relationships showed that the conjugated structure of carbonyl and exomethylene groups in I and I1 plays an important role in potent antifungal activity. However, it is noteworthy that compounds 53, 54, and 56, which have a ...

4-Acetylbiphenyl Structure

4-Acetylbiphenyl

Formaldehyde Structure

Dimethylamine hydrochloride Structure

Dimethylamine h...

~26%

3-dimethylamino-1-(4-phenylphenyl)propan-1-one Structure

3-dimethylamino...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-chlorophen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(4-CHLOROPHENYL)-2-(1H-1,2,4-TRIAZOLE-1-YL)-ETHANONE Structure

1-(4-CHLOROPHEN...

~%

1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-chlorophen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(4-methoxyphenyl)-2-(1,2,4-triazol-1-yl)ethanone Structure

1-(4-methoxyphe...

~%

1-(4-methoxyphenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-methoxyphe...

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure

3-(dimethylamin...

~%

1-[2-(4-methoxybenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-methoxy...

Acetanisole Structure

~%

1-[2-(4-methoxybenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-methoxy...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(3-(4-methoxyphenyl)-3-oxopropyl)pyridin-2(1H)-one Structure

1-(3-(4-methoxy...

~%

1-[2-(4-methoxybenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-methoxy...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(4-chlorophenyl)-2-oxoethyl)-1H-benzo[d]imidazol-2(3H)-one Structure

1-(2-(4-chlorop...

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-1H-benzimidazol-2-one Structure

3-[3-(4-chlorop...

4-Acetylbiphenyl Structure

4-Acetylbiphenyl

~%

1-(4-phenylphenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-phenylphen...

3-dimethylamino-1-(4-phenylphenyl)propan-1-one Structure

3-dimethylamino...

~%

1-(4-phenylphenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-phenylphen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-([1,1'-biphenyl]-4-yl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one Structure

1-([1,1'-biphen...

~%

1-(4-phenylphenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-phenylphen...

1-(4-Chlorophenyl)ethanone Structure

1-(4-Chlorophen...

~%

2-(4-chlorophenyl)-3-(4-oxoquinazolin-3-yl)propanal Structure

2-(4-chlorophen...

4-Quinazolinone Structure

4-Quinazolinone

1-(4-Chlorophenyl)-3-(dimethylamino)propan-1-one Hydrochloride Structure

1-(4-Chlorophen...

~%

2-(4-chlorophenyl)-3-(4-oxoquinazolin-3-yl)propanal Structure

2-(4-chlorophen...

AKOS B016267 Structure

Bis(dimethylamino)methane Structure

Bis(dimethylami...

~37%

2-phenyl-1-thiophen-2-ylprop-2-en-1-one Structure

2-phenyl-1-thio...

Phenylacetyl chloride Structure

Phenylacetyl ch...

~%

2-phenyl-1-thiophen-2-ylprop-2-en-1-one Structure

2-phenyl-1-thio...

2,4-Dichlorobenzyl cyanide Structure

2,4-Dichloroben...

~%

N-(4-chlorophenyl)-2-(2,4-dichlorophenyl)prop-2-enamide Structure

N-(4-chlorophen...

quinolone Structure

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinolin-2-one Structure

1-[3-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinolin-2-one Structure

1-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(4-chlorophenyl)-2-oxoethyl)quinolin-2(1H)-one Structure

1-(2-(4-chlorop...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinolin-2-one Structure

1-[3-(4-chlorop...

1-(4-Chlorophenyl)ethanone Structure

1-(4-Chlorophen...

~%

1-[2-(4-chlorobenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-chlorob...

1-(4-Chlorophenyl)-3-(dimethylamino)propan-1-one Hydrochloride Structure

1-(4-Chlorophen...

~%

1-[2-(4-chlorobenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-chlorob...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(3-(4-chlorophenyl)-3-oxopropyl)pyridin-2(1H)-one Structure

1-(3-(4-chlorop...

~%

1-[2-(4-chlorobenzoyl)prop-2-enyl]pyridin-2-one Structure

1-[2-(4-chlorob...

2-pyridone Structure

~%

1-[3-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2-methoxy...

1-(2-Methoxyphenyl)ethanone Structure

1-(2-Methoxyphe...

~%

1-[3-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2-methoxy...

o-methoxy phenacylbromide Structure

o-methoxy phena...

~%

1-[3-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2-methoxy...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(2-methoxyphenyl)-2-oxoethyl)pyridin-2(1H)-one Structure

1-(2-(2-methoxy...

~%

1-[3-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2-methoxy...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-2H-pyridine-3,6-dione Structure

1-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(4-chlorophenyl)-2-oxoethyl)-1,6-dihydropyrazine-2,5-dione Structure

1-(2-(4-chlorop...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-2H-pyridine-3,6-dione Structure

1-[3-(4-chlorop...

4-Quinazolinone Structure

4-Quinazolinone

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one Structure

3-[3-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one Structure

3-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

3-[2-(4-chlorophenyl)-2-oxoethyl]quinazolin-4-one Structure

3-[2-(4-chlorop...

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one Structure

3-[3-(4-chlorop...

4-Quinazolinone Structure

4-Quinazolinone

~%

3-[3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one Structure

3-[3-(4-methoxy...

PTP inhibitor 1 Structure

PTP inhibitor 1

~%

3-[3-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]quinazolin-4-one Structure

3-[3-(4-methoxy...

1(2H)-Phthalazinone Structure

1(2H)-Phthalazinone

~%

2-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]phthalazin-1-one Structure

2-[3-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

2-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]phthalazin-1-one Structure

2-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

2-(2-(4-chlorophenyl)-2-oxoethyl)phthalazin-1(2H)-one Structure

2-(2-(4-chlorop...

~%

2-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]phthalazin-1-one Structure

2-[3-(4-chlorop...

3-phenyl-1-(thiophen-2-yl)propan-1-one Structure

3-phenyl-1-(thi...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

~58%

2-benzyl-1-thiophen-3-ylprop-2-en-1-one Structure

2-benzyl-1-thio...

Benzenepropanenitrile Structure

Benzenepropanen...

~%

2-benzyl-1-thiophen-3-ylprop-2-en-1-one Structure

2-benzyl-1-thio...

Acetanisole Structure

~%

1-(4-methoxyphenyl)-3-(1,2,4-triazol-1-yl)propan-1-one Structure

1-(4-methoxyphe...

1,2,4-Triazole Structure

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure

3-(dimethylamin...

~%

1-(4-methoxyphenyl)-3-(1,2,4-triazol-1-yl)propan-1-one Structure

1-(4-methoxyphe...

2-Propionylfuran Structure

2-Propionylfuran

Bis(dimethylamino)methane Structure

Bis(dimethylami...

~%

1-(furan-2-yl)-2-methylprop-2-en-1-one Structure

1-(furan-2-yl)-...

5-chloro-2-pyridol Structure

5-chloro-2-pyridol

~%

5-chloro-1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

5-chloro-1-[3-(...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

5-chloro-1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

5-chloro-1-[3-(...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

5-chloro-1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-2(1H)-one Structure

5-chloro-1-(2-(...

~%

5-chloro-1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

5-chloro-1-[3-(...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(4-chlorophenyl)-2-(2-thienyl)-2-ethanone Structure

1-(4-chlorophen...

~%

2-(4-chlorophenyl)-1-thiophen-2-ylprop-2-en-1-one Structure

2-(4-chlorophen...

p-chlorophenylacetyl chloride Structure

p-chlorophenyla...

~%

2-(4-chlorophenyl)-1-thiophen-2-ylprop-2-en-1-one Structure

2-(4-chlorophen...

4'-Fluoroacetophenone Structure

4'-Fluoroacetop...

~%

1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-fluorophen...

p-Fluorophenacyl bromide Structure

p-Fluorophenacy...

~%

1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-fluorophen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(4-FLUOROPHENYL)-2-(1H-1,2,4-TRIAZOLE-1-YL)ETHANONE Structure

1-(4-FLUOROPHEN...

~%

1-(4-fluorophenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-fluorophen...

2-pyridone Structure

~%

1-[1-(4-chlorophenyl)-1-oxopent-2-en-2-yl]pyridin-2-one Structure

1-[1-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-[1-(4-chlorophenyl)-1-oxopent-2-en-2-yl]pyridin-2-one Structure

1-[1-(4-chlorop...

2-pyridone Structure

~%

1-(3-oxo-3-phenylprop-1-en-2-yl)pyridin-2-one Structure

1-(3-oxo-3-phen...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

1-(3-oxo-3-phenylprop-1-en-2-yl)pyridin-2-one Structure

1-(3-oxo-3-phen...

2(1H)-Pyridinone,1-(2-oxo-2-phenylethyl)- Structure

2(1H)-Pyridinon...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

~%

1-(3-oxo-3-phenylprop-1-en-2-yl)pyridin-2-one Structure

1-(3-oxo-3-phen...

Formaldehyde Structure

3-[2-(4-chlorophenyl)-2-oxoethyl]quinazolin-4-one Structure

3-[2-(4-chlorop...

~37%

3-[1-(4-chlorophenyl)-3-hydroxy-1-oxopropan-2-yl]quinazolin-4-one Structure

3-[1-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

3-[1-(4-chlorophenyl)-3-hydroxy-1-oxopropan-2-yl]quinazolin-4-one Structure

3-[1-(4-chlorop...

2-Bromo-1-(2-furyl)ethanone Structure

2-Bromo-1-(2-fu...

~%

1-(furan-2-yl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(furan-2-yl)-...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(furan-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethanone Structure

1-(furan-2-yl)-...

~%

1-(furan-2-yl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(furan-2-yl)-...

METHYL 6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE Structure

METHYL 6-OXO-1,...

~%

methyl 1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-6-oxopyridine-3-carboxylate Structure

methyl 1-[3-(4-...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

methyl 1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-6-oxopyridine-3-carboxylate Structure

methyl 1-[3-(4-...

Propionaldehyde Structure

Propionaldehyde

1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-2(1H)-one Structure

1-(2-(4-chlorop...

~47%

1-[1-(4-chlorophenyl)-1-oxopent-2-en-2-yl]pyridin-2-one Structure

1-[1-(4-chlorop...

1-(4-Chlorophenyl)ethanone Structure

1-(4-Chlorophen...

~%

1-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-chlorophen...

1-(4-Chlorophenyl)-3-(dimethylamino)propan-1-one Hydrochloride Structure

1-(4-Chlorophen...

~%

1-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-chlorophen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(4-chlorophenyl)-3-(1,2,4-triazol-1-yl)propan-1-one Structure

1-(4-chlorophen...

~%

1-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)prop-2-en-1-one Structure

1-(4-chlorophen...

4-Acetylbiphenyl Structure

4-Acetylbiphenyl

~%

1-[3-oxo-3-(4-phenylphenyl)prop-1-en-2-yl]pyridin-2-one Structure

1-[3-oxo-3-(4-p...

p-Bromoacetylbiphenyl Structure

p-Bromoacetylbi...

~%

1-[3-oxo-3-(4-phenylphenyl)prop-1-en-2-yl]pyridin-2-one Structure

1-[3-oxo-3-(4-p...

4-Quinazolinone Structure

4-Quinazolinone

~%

3-[1-(4-chlorophenyl)-3-hydroxy-1-oxopropan-2-yl]quinazolin-4-one Structure

3-[1-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

2-(2,4-Dichlorophenyl)-1-(4-fluorophenyl)ethan-1-one Structure

2-(2,4-Dichloro...

~66%

2-(2,4-dichlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one Structure

2-(2,4-dichloro...

Fluorobenzene Structure

~%

2-(2,4-dichlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one Structure

2-(2,4-dichloro...

(2,4-Dichlorophenyl)acetyl chloride Structure

(2,4-Dichloroph...

~%

2-(2,4-dichlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one Structure

2-(2,4-dichloro...

4-Fluorobenzaldehyde Structure

4-Fluorobenzaldehyde

1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-2(1H)-one Structure

1-(2-(4-chlorop...

~74%

1-[3-(4-chlorophenyl)-1-(4-fluorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

2-pyridone Structure

~%

1-[3-(4-chlorophenyl)-1-(4-fluorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-[3-(4-chlorophenyl)-1-(4-fluorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

2-(2,4-dichlorophenyl)-2',4'-dichloroacetophenone Structure

2-(2,4-dichloro...

~67%

1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one Structure

1,2-bis(2,4-dic...

1,3-Dichlorobenzene Structure

1,3-Dichlorobenzene

~%

1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one Structure

1,2-bis(2,4-dic...

(2,4-Dichlorophenyl)acetyl chloride Structure

(2,4-Dichloroph...

~%

1,2-bis(2,4-dichlorophenyl)prop-2-en-1-one Structure

1,2-bis(2,4-dic...

Pinacolone Structure

~%

4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-one Structure

4,4-dimethyl-2-...

1-Brom-3,3-dimethylbutan-2-on Structure

1-Brom-3,3-dime...

~%

4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-one Structure

4,4-dimethyl-2-...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

3,3-Dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one Structure

3,3-Dimethyl-1-...

~%

4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-one Structure

4,4-dimethyl-2-...

2-bromo-4'-methylacetophenone Structure

2-bromo-4'-meth...

~%

1-(4-methylphenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-methylphen...

2-Acetylthiophene Structure

2-Acetylthiophene

~%

1-thiophen-2-yl-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-thiophen-2-yl...

2-Bromo-1-(2-thienyl)ethanone Structure

2-Bromo-1-(2-th...

~%

1-thiophen-2-yl-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-thiophen-2-yl...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

(1,2,4-triazol-1-ylmethyl)-(thien-2-yl)-ketone Structure

(1,2,4-triazol-...

~%

1-thiophen-2-yl-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-thiophen-2-yl...

2-Bromo-2',4'-dichloroacetophenone Structure

2-Bromo-2',4'-d...

~%

1-(2,4-dichlorophenyl)-2-pyrazol-1-ylprop-2-en-1-one Structure

1-(2,4-dichloro...

2',4'-Dichloroacetophenone Structure

2',4'-Dichloroa...

~%

1-(2,4-dichlorophenyl)-2-pyrazol-1-ylprop-2-en-1-one Structure

1-(2,4-dichloro...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2',4'-dichlorophenacyl)pyrazole Structure

1-(2',4'-dichlo...

~%

1-(2,4-dichlorophenyl)-2-pyrazol-1-ylprop-2-en-1-one Structure

1-(2,4-dichloro...

PTP inhibitor 1 Structure

PTP inhibitor 1

~%

1-(4-methoxyphenyl)-2-(1,2,4-triazol-1-yl)prop-2-en-1-one Structure

1-(4-methoxyphe...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(4-chlorophenyl)-2-oxoethyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one Structure

1-(2-(4-chlorop...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]-3-methylbenzimidazol-2-one Structure

1-[3-(4-chlorop...

Ethanone,1-phenyl-2-(4-pyridinyl)- Structure

Ethanone,1-phen...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

~46%

1-phenyl-2-pyridin-4-ylprop-2-en-1-one Structure

1-phenyl-2-pyri...

benzene Structure

~%

1-phenyl-2-pyridin-4-ylprop-2-en-1-one Structure

1-phenyl-2-pyri...

1-(4-Chlorophenyl)ethanone Structure

1-(4-Chlorophen...

~%

1-(4-chlorophenyl)-3-(1,2,4-triazol-1-yl)propan-1-one Structure

1-(4-chlorophen...

1,2,4-Triazole Structure

1-(4-Chlorophenyl)-3-(dimethylamino)propan-1-one Hydrochloride Structure

1-(4-Chlorophen...

~%

1-(4-chlorophenyl)-3-(1,2,4-triazol-1-yl)propan-1-one Structure

1-(4-chlorophen...

2-pyridone Structure

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-2(1H)-one Structure

1-(2-(4-chlorop...

~%

1-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(4-chlorop...

2-pyridone Structure

~%

1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2,4-dichl...

2-Bromo-2',4'-dichloroacetophenone Structure

2-Bromo-2',4'-d...

~%

1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2,4-dichl...

2',4'-Dichloroacetophenone Structure

2',4'-Dichloroa...

~%

1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2,4-dichl...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

1-[2-(2,4-dichlorophenyl) -2-oxoethyl]hydropyridin-2-one Structure

1-[2-(2,4-dichl...

~%

1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one Structure

1-[3-(2,4-dichl...

2-Bromo-4'-chloroacetophenone Structure

2-Bromo-4'-chlo...

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyrimidin-4-one Structure

3-[3-(4-chlorop...

Bis(dimethylamino)methane Structure

Bis(dimethylami...

3-(2-(4-chlorophenyl)-2-oxoethyl)pyrimidin-4(3H)-one Structure

3-(2-(4-chlorop...

~%

3-[3-(4-chlorophenyl)-3-oxoprop-1-en-2-yl]pyrimidin-4-one Structure

3-[3-(4-chlorop...