m-PEG3-CH2COOH
Modify Date: 2024-01-09 12:43:56
m-PEG3-CH2COOH structure
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Common Name | m-PEG3-CH2COOH | ||
|---|---|---|---|---|
| CAS Number | 16024-60-5 | Molecular Weight | 222.23600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H18O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of m-PEG3-CH2COOHm-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs. |
| Name | 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs. |
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| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C9H18O6 |
|---|---|
| Molecular Weight | 222.23600 |
| Exact Mass | 222.11000 |
| PSA | 74.22000 |
| Hazard Codes | Xi |
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m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: ISIS PHARMACEUTICALS, INC.; BUCHARDT, Dorte; NIELSEN, Peter Eigil; EGHOLM, Michael Patent: EP804456 B1, 2002 ; |
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~82%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Zech, Oliver; Kellermeier, Matthias; Thomaier, Stefan; Maurer, Eva; Klein, Regina; Schreiner, Christian; Kunz, Werner Chemistry - A European Journal, 2009 , vol. 15, # 6 p. 1341 - 1345 |
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~30%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Rerat, Vincent; Dive, Georges; Cordi, Alex A.; Tucker, Gordon C.; Bareille, Reine; Amedee, Joelle; Bordenave, Laurence; Marchand-Brynaert, Jacqueline Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7029 - 7043 |
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~96%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Simeone, Luca; Mangiapia, Gaetano; Vitiello, Giuseppe; Irace, Carlo; Colonna, Alfredo; Ortona, Ornella; Montesarchio, Daniela; Paduano, Luigi Bioconjugate Chemistry, 2012 , vol. 23, # 4 p. 758 - 770 Title/Abstract Full Text View citing articles Show Details Simeone, Luca; Mangiapia, Gaetano; Irace, Carlo; Di Pascale, Antonio; Colonna, Alfredo; Ortona, Ornella; De Napoli, Lorenzo; Montesarchio, Daniela; Paduano, Luigi Molecular BioSystems, 2011 , vol. 7, # 11 p. 3075 - 3086 |
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~96%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Haines, Alan H.; Karntiang, Pipat Carbohydrate Research, 1980 , vol. 78, p. 205 - 211 |
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~%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Heidkamp, Katharina; Aytemir, Memet; Vorlop, Klaus-Dieter; Pruesse, Ulf Catalysis Science and Technology, 2013 , vol. 3, # 11 p. 2984 - 2992 |
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~%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Simeone, Luca; Mangiapia, Gaetano; Vitiello, Giuseppe; Irace, Carlo; Colonna, Alfredo; Ortona, Ornella; Montesarchio, Daniela; Paduano, Luigi Bioconjugate Chemistry, 2012 , vol. 23, # 4 p. 758 - 770 Title/Abstract Full Text View citing articles Show Details Simeone, Luca; Mangiapia, Gaetano; Irace, Carlo; Di Pascale, Antonio; Colonna, Alfredo; Ortona, Ornella; De Napoli, Lorenzo; Montesarchio, Daniela; Paduano, Luigi Molecular BioSystems, 2011 , vol. 7, # 11 p. 3075 - 3086 |
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~%
m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Hu, Wei; Yan, Qifan; Zhao, Dahui Chemistry - A European Journal, 2011 , vol. 17, # 25 p. 7087 - 7094 |
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m-PEG3-CH2COOH CAS#:16024-60-5 |
| Literature: Tuchscherer; Schaarschmidt; Schulze; Hietschold; Lang Dalton Transactions, 2012 , vol. 41, # 9 p. 2738 - 2746 |
| (monomethoxy)triethylene glycol acetic acid |
| 2-(2-(2-methoxyethoxy)-ethoxy)-ethoxy-acetic acid |
| 3,6,9,12-tetraoxatridecanoic acid |
| CH3O-TEG acetic acid |
| 2,5,8,11-Tetraoxatridecan-13-oic acid |