Peucedanocoumarin II can induce rice resistance to blast disease[1].
Big Endothelin-3 (22-41) amide (human) is a biologically active peptide.
3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluoro uridine-2’-CED-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
(S)-2-(2-((tert-Butoxycarbonyl)amino)propanamido)acetic acid is a Glycine (HY-Y0966) derivative[1].
H-Ala-Hyp-OH is a biological active peptide.
Hydroxyfenbendazole-d3 is the deuterium labeled Hydroxyfenbendazole.
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity[1].
W-84 (dibromide) is a potent allosteric modulator of M2-cholinoceptors, which retards [3H]N-methylscopolamine dissociation. W-84 dibromide can stabilize cholinergic antagonist-receptor complexes. W-84 (dibromide) is a non-competitive muscarinic acetylcholine receptors antagonist with allosteric effects. W-84 (dibromide) protects over additively against an organophosphate-intoxication when applied in combination with atropine[1][2][3].
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues[1].
Vinyln-Octanoate(stabilizedwithMEHQ) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM.
H-Ser-Ala-OH is a biologically active peptide.
(S,E)-Cyclooct-2-enol is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
3-O-Acetyl-11-hydroxy-beta-boswellic acid is a potent 5-lipoxygenase (5-LO) inhibitor[1].
TSPO ligand-1 is the ligand of AUTAC4 (HY-134640) that can be used in the synthesis of PROTACs. TSPO ligand-1 is a mitochondrial outer membrane transmembrane structural domain protein can bind to AUTAC4 and regulate mitochondrial autophagy to promote targeted mitochondrial renewal. TSPO ligand-1 is also involved in the transport of cholesterol from the outer to inner mitochondrial membrane and serves as a sensitive biomarker of brain injury and neurodegeneration[1][2].
2-Phenoxy-1-phenylethanol-d1is the deuterium labeled2-Phenoxy-1-phenylethanol(HY-W006550)[1].
Lansiumarin C, a lansiumarin, can be isolated from the branches of Clausena lansium (Rutaceae)[1].
Nifedipine D6 is deuterium labeled nifedipine, and nifedipine is a potent calcium channel blocker.
Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
((4-(O-tolyloxy)phenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].
L-Phenylalanine benzyl ester (hydrochloride) is a phenylalanine derivative[1].
Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. Hoechst 33258 is a cell dye for DNA quantitation.IC50 Value:These Bis-benzimides were originally developed by Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similarexcitation/emission spectra. Both dyes are excited by ultraviolet light at around 350 nm, and both emit blue/cyan fluorescent light around anemission maximum at 461 nm. Unbound dye has its maximum fluorescence emission in the 510-540 nm range. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 mg/mL. Aqueous solutions are stable at 2-6 °C for at least six months when protected from light. For long-term storage the solutions are instead frozen at ≤-20 °C.The dyes bind to the minor groove of double-stranded DNA with a preference for sequences rich in adenine andthymine. Although the dyes can bind to all nucleic acids, AT-rich double-stranded DNA strands enhance fluorescence considerably.Hoechst dyes are cell-permeable and can bind to DNA in live or fixed cells. Therefore, these stains are often called supravital, which means that cells survive a treatment with these compounds. Cells that express specific ATP-binding cassette transporter proteins can also actively transport these stains out of their cytoplasm.
3-Hydroxyhexadecanoic Acid Methyl Ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
DC-Srci-6649 is a c-Src kinase inhibitor that inhibits the phosphorylation and locks c-Src in the inactive state.
3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
PCI-33380 is an irreversible Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe).
Cy7.5 maleimide is a near infrared fluorescent (NIRF) dye that can be used in labeling protein sulfhydryl (-SH) groups and in vivo imaging[1].
Unguisin B s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis[1].
Tristearin is a triglyceride derived from three units of stearic acid[1].
SDGR is a Ser-Asp-Gly-Arg tetrapeptide sequence that effectively inhibits fibronectin-mediated cell attachment[1]