Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Adenosine 5′-monophosphoramidate sodium

Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP[1].

  • CAS Number: 102029-68-5
  • MF: C10H14N6NaO6P
  • MW: 368.21800
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Tyr(tBu)-OPfp

Fmoc-Tyr(tBu)-OPfp is a tyrosine derivative[1].

  • CAS Number: 86060-93-7
  • MF: C34H28F5NO5
  • MW: 625.58200
  • Catalog: Others
  • Density: 1.334 g/cm3
  • Boiling Point: 713.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

ajugose

Ajugose is a hexasaccharide that can be isolated from in the seeds of Vigna mungo L.[1].

  • CAS Number: 512-72-1
  • MF: C36H62O31
  • MW: 990.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sotirimod

Sotirimod is an immunostimulant, and can potentially treat for actinic keratosis.

  • CAS Number: 227318-75-4
  • MF: C14H17N5
  • MW: 255.31800
  • Catalog: Others
  • Density: 1.33g/cm3
  • Boiling Point: 493.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 252.5ºC

Camptothecin analog-1

Camptothecin analog-1 (Comp 166) is a camptothecin analog[1].

  • CAS Number: 2873460-51-4
  • MF: C23H23FN4O6S
  • MW: 502.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cy7.5 carboxylic acid

Cyanine7.5 carboxylic is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid functional groups. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Cyanine7.5 carboxylic can be covalently bound to some biological molecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.

  • CAS Number: 1686147-68-1
  • MF: C45H48N2O2
  • MW: 648.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Suc-Gly-Gly-Phe-pNA

Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an Km value of 1.6 mM[1][2].

  • CAS Number: 68982-90-1
  • MF: C23H25N5O8
  • MW: 499.47300
  • Catalog: Proteasome
  • Density: 1.401g/cm3
  • Boiling Point: 1005.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 562ºC

9-Fluorenylmethyl carbazate

9-Fluorenylmethyl carbazate is used as a fluorophore reagent for a fluorimetric detection of glycans[1].

  • CAS Number: 35661-51-9
  • MF: C15H14N2O2
  • MW: 254.284
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 485.8±14.0 °C at 760 mmHg
  • Melting Point: -170ºC (dec.)
  • Flash Point: 247.6±20.1 °C

Z-D-Asp-OH

Z-D-Asp-OH is an aspartic acid derivative[1].

  • CAS Number: 78663-07-7
  • MF: C12H13NO6
  • MW: 267.235
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 472.8±45.0 °C at 760 mmHg
  • Melting Point: 117ºC
  • Flash Point: 239.7±28.7 °C

D-Fructose-d-2

D-Fructose-d-2 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].

  • CAS Number: 80599-66-2
  • MF: C6H11DO6
  • MW: 181.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-TFA-ap-7-Deaza-ddG

7-TFA-ap-7-Deaza-ddG (compound 19d, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].

  • CAS Number: 114748-68-4
  • MF: C16H16F3N5O4
  • MW: 399.324
  • Catalog: DNA/RNA Synthesis
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-O-HEXADECYL-2-[CIS-8,11,14-EICO-SATRIENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE

Dihomo-γ-Linolenoyl PAF C-16 is a PAF analog that contains dihomo-γ-linolenoate at the sn-2 position instead of the acetate moiety in PAF C-16. The biological activity of dihomo-γ-linolenoyl PAF C-16 is currently unknown but may be similar to that of arachidonoyl PAF C-16.

  • CAS Number: 155575-01-2
  • MF: C44H84NO7P
  • MW: 770.114
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Methionine, L-valyl

(S)-2-((S)-2-Amino-3-methylbutanamido)-4-(methylthio)butanoic acid is a Methionine (HY-13694) derivative[1].

  • CAS Number: 14486-09-0
  • MF: C10H20N2O3S
  • MW: 248.34200
  • Catalog: Others
  • Density: 1.166g/cm3
  • Boiling Point: 486.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 248.2ºC

Caspase-3 Substrate

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate.

  • CAS Number: 958001-92-8
  • MF: C30H38N6O12
  • MW: 674.656
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1211.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 686.3±34.3 °C

Sesame Oil

Sesame Oil can be used as an excipient, such as Oil-soluble substance carrier, solvent, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • Density: 0.919g/mL
  • Boiling Point: N/A
  • Melting Point: -5 °C
  • Flash Point: 255 °C

Maurocalcine

Maurocalcine is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. Maurocalcine induces [3H]ryanodine binding on RyR1 with an EC50 value of 2558 nM. Maurocalcine exhibits a apparent affinity of 14 nM for RyR2. Maurocalcine can be applied to in vivo cell tracking or other cell imaging techniques[1][2][3].

  • CAS Number: 269745-22-4
  • MF: C156H270N56O46S6
  • MW: 3858.55
  • Catalog: Calcium Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-His(Trt)-OH-15N3

Fmoc-His(Trt)-OH-15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].

  • CAS Number: 1217696-12-2
  • MF: C40H3315N3O4
  • MW: 622.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganoderic acid S

Ganoderic acid S1 (compound 4) is a natural product that can be found in ganoderma lucidum[1].

  • CAS Number: 104759-35-5
  • MF: C30H44O3
  • MW: 452.67
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 584.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 321.5±26.6 °C

1,4,4-Trimethyl-L-proline

1,4,4-Trimethyl-L-proline is a proline derivative[1].

  • CAS Number: 1443245-02-0
  • MF: C8H15NO2
  • MW: 157.2102
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 235.3±33.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 96.1±25.4 °C

Taxuyunnanine

Paclitaxel C is a compound that can be found in taxus cutting[1].

  • CAS Number: 153415-45-3
  • MF: C46H57NO14
  • MW: 847.94
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 932.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 517.6±34.3 °C

H-Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL)-OH

Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL) is a calpain substrate. The excitation wavelength is 380 nm and the emission wavelength is 500 nm for Glu(Edans)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(Dabcyl)[1].

  • CAS Number: 1914987-47-5
  • MF: C72H97N17O16S
  • MW: 1488.710
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Amino-4-methylquinolin-2(1H)-one

Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion[1][2].

  • CAS Number: 19840-99-4
  • MF: C10H10N2O
  • MW: 174.199
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 417.6±45.0 °C at 760 mmHg
  • Melting Point: >275ºC (dec.)
  • Flash Point: 206.4±28.7 °C

Strychnistenolide

Strychnistenolide is a sesquiterpene lactone that can be isolated from the roots of Lindera strychnifolia. Strychnistenolide exists as a single stereoisomer in CHCl3, but exomeric in pyridine[1].

  • CAS Number: 332372-09-5
  • MF: C15H18O4
  • MW: 262.301
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 492.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.0±22.2 °C

Simridarlimab

Simridarlimab is a humanized IG antibody targeting CD274/CD47[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glutaryl-L-phenylalanine 7-amido-4-methylcoumarin

Glut-Phe-AMC is a fluorescent dye.

  • CAS Number: 58632-47-6
  • MF: C24H24N2O6
  • MW: 436.45700
  • Catalog: Others
  • Density: 1.327 g/cm3
  • Boiling Point: 807.4ºCat 760 mmHg
  • Melting Point: N/A
  • Flash Point: 442.1ºC

16-Epipyromesaconitine

16-Epipyromesaconitine is a natural product that can be obtained by the pyrolysis of Mesaconitine (HY-N0724)[1].

  • CAS Number: 132054-38-7
  • MF: C24H37NO8
  • MW: 467.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzylthiouracil

Benzylthiouracil is an active pharmaceutical ingredient against hyperthyroidism[1].

  • CAS Number: 6336-50-1
  • MF: C11H10N2OS
  • MW: 218.27500
  • Catalog: Others
  • Density: 1.32g/cm3
  • Boiling Point: 438.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.8ºC

RyRs activator 3

RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1].

  • CAS Number: 2850333-35-4
  • MF: C23H19BrCl2N6O3
  • MW: 578.25
  • Catalog: Calcium Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oligo-1,6-glucosidase

Oligo-1,6-glucosidase belongs to the α-amylase family that catalyzes the exo hydrolysis of α-1,6-glucoside bonds from the nonreducing ends of panose, palatinose, α-limit dextrins, and isomaltooligosaccharides[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pyraflufen

Pyraflufen-ethyl is a phenylpyrazole herbicide for control of annual and perennial broadleaf weeds[1].

  • CAS Number: 129630-19-9
  • MF: C15H13Cl2F3N2O4
  • MW: 413.18
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 468.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.4±27.3 °C