Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Efpegsomatropin

Efpegsomatropin is an active peptide. Efpegsomatropin can be used for various biochemical studies.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FD-1080 free acid

FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].

  • CAS Number: 1151888-25-3
  • MF: C40H39ClN2O6S2
  • MW: 743.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BPH-1086

BPH-1086 (compound 10) is an IspH inhibitor, IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome[1][2].

  • CAS Number: 1226901-43-4
  • MF: C4H8O7P2
  • MW: 230.05
  • Catalog: Bacterial
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phytic acid sodium salt

Phytic acid sodium salt (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphat) is often present in legume seeds with antinutritional effects. Phytic acid sodium salt is a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. phytic acid is hydrolyzed by phytases in a stepwise manner in the plant[1].

  • CAS Number: 14306-25-3
  • MF: C6H18O24P6.xNa
  • MW: 923.817
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 1190.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 673.9ºC

D-2-Thiolhistidine

D-2-Thiolhistidine can be used for modification of proteins and peptides.

  • CAS Number: 1195264-93-7
  • MF: C6H9N3O2S
  • MW: 187.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Inositol 1,3,4,5-tetraphosphate

Inositol 1,3,4,5-tetraphosphate is the head group of PIP3 (phosphatidylinositol 3,4,5-trisphosphate)[1].

  • CAS Number: 102850-29-3
  • MF: C6H16O18P4
  • MW: 517.10600
  • Catalog: Others
  • Density: 2.32 g/cm3
  • Boiling Point: 1015.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 568ºC

Brilliant blue G-250

Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome[1][2][3].

  • CAS Number: 6104-58-1
  • MF: C47H48N3NaO7S2
  • MW: 854.020
  • Catalog: Others
  • Density: >1.0 g/cm3 (20ºC)
  • Boiling Point: N/A
  • Melting Point: 100 °C
  • Flash Point: 11 °C

cannabispirol

β-Cannabispiranol (Cannabispirol) is a spiro-compound that can be isoalted from Thailand Cannabis[1].

  • CAS Number: 64052-90-0
  • MF: C15H20O3
  • MW: 248.318
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 438.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.7±28.7 °C

GJ103 sodium salt

GJ103 sodium salt is an active analog of the read-through compound GJ072.

  • CAS Number: 1459687-96-7
  • MF: C16H13N4NaO3S
  • MW: 364.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trypan red

Trypan red is a vital stain.

  • CAS Number: 574-64-1
  • MF: C32H19N6Na5O15S5
  • MW: 1002.80000
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CER1 (d18:1/26:0/18:1)-d9

CER1 (d18:1/26:0/18:1)-d9 is deuterium labeled CER1 (d18:1/26:0/18:1).

  • CAS Number: 2260670-32-2
  • MF: C62H110D9NO5
  • MW: 967.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Fmoc-trans-4-hydroxy-L-proline methyl ester

(2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is a proline derivative[1].

  • CAS Number: 122350-59-8
  • MF: C21H21NO5
  • MW: 367.39500
  • Catalog: Others
  • Density: 1.329g/cm3
  • Boiling Point: 539.04ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 279.801ºC

PF 4800567

PF-4800567 is a potent and selective inhibitor of casein kinase 1ϵ (CK1ϵ), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).

  • CAS Number: 1188296-52-7
  • MF: C17H18ClN5O2
  • MW: 359.810
  • Catalog: Casein Kinase
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 592.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 312.4±30.1 °C

6-Aminofluorescein

6-Aminofluorescein (6-AF) is a new fluorescence marker.

  • CAS Number: 51649-83-3
  • MF: C20H13NO5
  • MW: 347.321
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 706.7±60.0 °C at 760 mmHg
  • Melting Point: 285 °C (dec.)(lit.)
  • Flash Point: 381.2±32.9 °C

6-((4,6-DICHLORO-1,3,5-TRIAZIN-2-YL)AMINO)-3',6'-DIHYDROXY-3H-SPIRO[ISOBENZOFURAN-1,9'-XANTHEN]-3-ONE HYDROCHLORIDE

6-DTAF hydrochloride is a fluorescein that can be used to label peptides and nucleotides[1].

  • CAS Number: 118357-32-7
  • MF: C23H13Cl3N4O5
  • MW: 531.73200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,5-DIBROMO-2-PENTYLACETATE

MTH-DL-Methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 877-49-6
  • MF: C7H12N2OS2
  • MW: 204.31300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jarin-1

Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana; impairs the activity of JA-Ile synthetase, thereby preventing the synthesis of the active hormone, JA-Ile, whereas closely related enzymes are not affected; A useful chemical tool in search for missing regulatory components and further dissection of the complex jasmonate signaling networks.

  • CAS Number: 1212704-51-2
  • MF: C28H29N3O4
  • MW: 471.557
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chrysoeriol-7-O-glucoside

Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].

  • CAS Number: 19993-32-9
  • MF: C22H22O11
  • MW: 462.404
  • Catalog: Cytochrome P450
  • Density: 1.609
  • Boiling Point: 801.6±65.0 °C at 760 mmHg
  • Melting Point: 176-179 ºC
  • Flash Point: 281.0±27.8 °C

Cecropin B (free acid) trifluoroacetate salt

Cecropin B (free acid) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 203265-23-0
  • MF: C176H301N51O42S
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucidenic acid E

Lucidenic acid E is a terpenoid from Ganoderma lucidum[1].

  • CAS Number: 98665-17-9
  • MF: C29H40O8
  • MW: 516.62300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,4,6-Tri-O-acetyl-D-glucal-13C-2

3,4,6-Tri-O-acetyl-D-glucal-13C-2 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal[1].

  • CAS Number: 478529-37-2
  • MF: C12H16O7
  • MW: 273.24400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganosporeric acid A

Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. Ganosporeric acid A can be used for the research of liver injury[1].

  • CAS Number: 135357-25-4
  • MF: C30H38O8
  • MW: 526.62
  • Catalog: Others
  • Density: 1.26g/cm3
  • Boiling Point: 685.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 382.2ºC

Propyliodone

Propyliodone is a compound used as a contrast medium in bronchography[1][2].

  • CAS Number: 587-61-1
  • MF: C10H11I2NO3
  • MW: 447.00800
  • Catalog: Others
  • Density: 2.14g/cm3
  • Boiling Point: 392.6ºC at 760mmHg
  • Melting Point: 186°C
  • Flash Point: 191.2ºC

Ac-Ile-Glu-Pro-Asp-AMC

Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

  • CAS Number: 216757-33-4
  • MF: C32H41N5O11
  • MW: 671.69
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1116.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 628.7±34.3 °C

1-(4'-thio-beta-ribofuranosyl)thymine

N6-Methyl-2-methyl thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 6741-71-5
  • MF: C10H14N2O5S
  • MW: 274.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BZL-ILE-OH

N-Benzyl-L-isoleucine is an isoleucine derivative[1].

  • CAS Number: 1859-49-0
  • MF: C13H19NO2
  • MW: 221.29500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aminoluciferin

6’-Amino-D-luciferin is a D-luciferin (HY-12591A) with its 6-position hydroxyl group substituted with an amino group. D-luciferin is the natural substrate of the enzyme luciferase (Luc)[1].

  • CAS Number: 161055-47-6
  • MF: C11H9N3O2S2
  • MW: 279.338
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 594.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 313.6±32.9 °C

M2I-1

M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays.

  • CAS Number: 312271-03-7
  • MF: C19H24N4O4S
  • MW: 404.483
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DLin-M-K-DMA

DLin-M-K-DMA (DLin-M-C2-DMA) is a cationic lipid that can be used in the construction of biological delivery vectors[1].

  • CAS Number: 1221271-55-1
  • MF: C42H77NO2
  • MW: 628.07
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrabutylammonium Tetraphenylborate

Tetrabutylammonium tetraphenylborate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 15522-59-5
  • MF: C40H56BN
  • MW: 561.690
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 230-236ºC(lit.)
  • Flash Point: N/A