Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Retrocyclin-101

Retrocyclin-101 is an antimicrobial peptide against of bacterial and viral[1].

  • CAS Number: 536757-16-1
  • MF: C74H130N28O19S6
  • MW: 1908.39
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methylsyringol

4-Methylsyringol is a natural product that can be isolated from hardwood[1].

  • CAS Number: 6638-05-7
  • MF: C9H12O3
  • MW: 168.19
  • Catalog: Others
  • Density: 1.105g/cm3
  • Boiling Point: 145-146 °C14 mm Hg(lit.)
  • Melting Point: 37-42 °C(lit.)
  • Flash Point: >230 °F

Paucinervin A

Paucinervin A (Compound 1) is a type of bittern.Paucinervin A inhibits the growth of HeLa cells (IC50=29.5μM). Paucinervin A is isolated from the natural Garcinia paucinervis [1].

  • CAS Number: 1243249-16-2
  • MF: C24H26O7
  • MW: 426.46
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 649.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 222.5±25.0 °C

2,2-Dimethylbutanoic acid-d11

2,2-Dimethylbutanoic acid-d11 is the deuterium labeled 2,2-Dimethylbutanoic acid[1].

  • CAS Number: 1219804-04-2
  • MF: C6HD11O2
  • MW: 127.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cy5.5-SE

Cy5.5-SE is a cyanine dye, labeling amino-groups in peptides, proteins, and oligonucleotides.

  • CAS Number: 442912-55-2
  • MF: C45H47N3O16S4
  • MW: 1014.13000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ferric oxide

Ferric oxide, red can be used as an excipient, such as colorant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 1309-37-1
  • MF: Fe2O3
  • MW: 159.69
  • Catalog: Others
  • Density: 5.24
  • Boiling Point: N/A
  • Melting Point: 1538ºC
  • Flash Point: >230°F

ML-329

ML329 is a small molecule inhibitor of MITF; inhibits TRPM-1 promoter activity with an IC50 of 1.2 μM.

  • CAS Number: 19992-50-8
  • MF: C16H12N2O4S
  • MW: 328.34200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S0456

S0456 is a near-infrared (NIR) fluorescent dye with an excitation (Ex) of 788 nM and emission (Em) of 800 nM. S0456 binds to the folate receptor (FR). S0456 can be used as a tumor-specific optical imaging agent[1].

  • CAS Number: 1252007-83-2
  • MF: C38H44ClN2Na3O12S4
  • MW: 953.44
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-Epiafzelechin-3-O-gallate

(-)-Epiafzelechin-3-O-gallate is a natural product that can be isolated from the water extract of Pu-erh tea. (-)-Epiafzelechin-3-O-gallate shows antioxidant activity[1].

  • CAS Number: 108907-43-3
  • MF: C22H18O9
  • MW: 426.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Yunnancoronarin A

Yunnancoronarin A (Zerumbetol) can be isolated from Hedychium forrestii. Yunnancoronarin A is cytotoxic, with IC50 values of 11.08 and 2.19 μM against lung adenocarcinoma cells A549 and leukemia cells K562, respectively[1].

  • CAS Number: 162762-93-8
  • MF: C20H28O2
  • MW: 300.435
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 399.6±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 195.4±27.9 °C

Schibitubin I

Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata[1].

  • CAS Number: 1609628-72-9
  • MF: C22H26O7
  • MW: 402.44
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Indoleacetic acid-D5

3-Indoleacetic acid-D5 (Indole-3-acetic acid-D5) is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-D5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

  • CAS Number: 76937-78-5
  • MF: C10H4D5NO2
  • MW: 180.21500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 165-169ºC(lit.)
  • Flash Point: N/A

Neocurdione

Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice[1].

  • CAS Number: 108944-67-8
  • MF: C15H24O2
  • MW: 236.35000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Chloro Trazodone hydrochloride

4-Chloro Trazodone hydrochloride is an isomer of Trazodone hydrochloride (HY-B0478). Trazodone hydrochloride is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders[1].

  • CAS Number: 1263278-77-8
  • MF: C19H23Cl2N5O
  • MW: 408.32500
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BDP R6G azide

BDP R6G azide is an anlong of BDP dye. BDP R6G azide is available that are tuned to match excitation and emission channels of classical xanthene and cyanine dyes. BDP R6G azide can be used in copper-catalyzed Click chemistry reactions with alkynes, DBCO and BCN. (λex=530 nm, λem=548 nm)[1].

  • CAS Number: 2183473-23-4
  • MF: C21H21BF2N6O
  • MW: 422.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biliverdine

Biliverdin is the product of the oxidation of bilirubin. Biliverdin can be synthesized via a non-protoporphyrin pathway in Corynebacterium glutamicum[1].

  • CAS Number: 114-25-0
  • MF: C33H34N4O6
  • MW: 582.65
  • Catalog: Others
  • Density: 1.3g/cm3
  • Boiling Point: N/A
  • Melting Point: >200ºC (dec.)
  • Flash Point: N/A

N-Methyl-L-phenylalanine

(S)-2-(Methylamino)-3-phenylpropanoic acid is a phenylalanine derivative[1].

  • CAS Number: 2566-30-5
  • MF: C10H13NO2
  • MW: 179.21600
  • Catalog: Others
  • Density: 1.126g/cm3
  • Boiling Point: 308.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 140.3ºC

Eugenin

Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity[1].

  • CAS Number: 480-34-2
  • MF: C11H10O4
  • MW: 206.19500
  • Catalog: Cardiovascular Disease
  • Density: 1.309g/cm3
  • Boiling Point: 389.2ºC at 760 mmHg
  • Melting Point: 118-119 °C
  • Flash Point: 157.2ºC

Araloside V

Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata[1].

  • CAS Number: 340963-86-2
  • MF: C54H88O23
  • MW: 1105.263
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mudanpioside J

Mudanpioside J, a monoterpene glycoside, is a metabolite of cortex moutan[1][2].

  • CAS Number: 262350-52-7
  • MF: C31H34O14
  • MW: 630.59300
  • Catalog: Others
  • Density: 1.61±0.1g/ml
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acebilustat

Acebilustat is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug.

  • CAS Number: 943764-99-6
  • MF: C29H27N3O4
  • MW: 481.542
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 649.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 346.3±34.3 °C

PrPSc-IN-1

PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1].

  • CAS Number: 1315475-30-9
  • MF: C22H17N5O
  • MW: 367.40
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Puerarin-4'-O-β-D-glucopyranoside

Puerarin-4'-O-β-D-glucopyranoside (compound 8) is a isoflavone from Pueraria lobata root (PLR). Puerarin-4'-O-β-D-glucopyranoside has estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells[1].

  • CAS Number: 117047-08-2
  • MF: C27H30O14
  • MW: 578.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Guancydine

Guancydine (Guancidine) is an antihypertensive agent[1].

  • CAS Number: 1113-10-6
  • MF: C7H14N4
  • MW: 154.21
  • Catalog: Cardiovascular Disease
  • Density: 1.02g/cm3
  • Boiling Point: 239.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 98.5ºC

Dixyrazine

Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.

  • CAS Number: 2470-73-7
  • MF: C24H33N3O2S
  • MW: 427.60300
  • Catalog: Neurological Disease
  • Density: 1.166g/cm3
  • Boiling Point: 590ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 310.6ºC

Clomifene

Clomifene is an orally active compound used for infertility. Clomifene is a simple, relatively safe, easily administered and well-tolerated efficacious compound to induce ovulation[1].

  • CAS Number: 911-45-5
  • MF: C26H28ClNO
  • MW: 405.96000
  • Catalog: Endocrinology
  • Density: 1.104g/cm3
  • Boiling Point: 509ºC at 760mmHg
  • Melting Point: 117.25°C
  • Flash Point: 261.6ºC

Euphorbetin

Euphorbetin, isolated from the ethyl acetate extract of the dried whole plants of Viola yedoensis Makino, exhibits anticoagulant activities[1].

  • CAS Number: 35897-99-5
  • MF: C18H10O8
  • MW: 354.26700
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dazopride

Dazopride is an antiemetic agent.

  • CAS Number: 70181-03-2
  • MF: C15H23ClN4O2
  • MW: 326.82200
  • Catalog: Others
  • Density: 1.27g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phalloidin-FITC

Phalloidin-FITC, a green fluorescent cytoskeleton stain, binds and labels F-actin. For most fluorescent imaging applications, cells should to be fixed and permeablilized. Excitation/emission maxima λ ~496/516 nm.

  • CAS Number: 915026-99-2
  • MF: C56H60N10O15S2
  • MW: 1177.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-formyl-dl-alanine

N-Formyl-DL-alanine is an alanine derivative[1].

  • CAS Number: 5893-10-7
  • MF: C4H7NO3
  • MW: 117.10300
  • Catalog: Others
  • Density: 1.223g/cm3
  • Boiling Point: 386.6ºC at 760mmHg
  • Melting Point: 150ºC
  • Flash Point: 187.6ºC