Conopressin S, isolated from Conus striatus, shows high affinity with vasopressin V1b receptor (AVPR1B), with a Ki of 8.3 nM[1].
Columbamine (Columbamin; Dehydroisocorypalmine) chloride is an alkaloid[1].
Sodium metabisulfite can be used as an excipient, such as antibacterial agent, preservative, antioxidant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture.
PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools[1].
(±)-Fluoxetine-dd5 Oxalate (phenyl-dd5) is the deuterium labeled (±)-Fluoxetine Oxalate[1].
Hypoxanthine-13C2,15N-1 is a 15N-labeled and 13C-labled 4-Hydroxyestrone[1].
1-Methyl-imidazole-d3 is the deuterium labeled 1-Methylimidazole[1].
Saucerneol is a lignans that can be isolated from Saururus chinensis. Saucerneol inhibits LPS-induced or Con A-induced lymphocytes proliferation. Saucerneol inhibits mixed lymphocyte response. Saucerneol also inhibits mitogens-induced cytokines secretion[1].
Cyclo(Pro-Thr) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
Lutein palmitate stearate is a lutein ester that can be found in Marigold flowers (Tagetes erecta)[1].
Prednisolone 21-acetate is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.
Ro 14-7437 is a potent and selective potentiating antagonist of Midazolam[1].
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells[1][2].
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH)[1].
Eupahualin C is a sesquiterpene lactone that can be isolated from Eupatorium hualienense. Eupahualin C shows cytotoxicity to K562 and U2OS cancer cells[1].
(R)-Boc-3,4-dimethoxy-β-Phe-OH is a phenylalanine derivative[1].
Polyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2].
WAY-639872 is an active molecule.
(2R,2'R)-Di-tert-butyl 3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride is a cysteine derivative[1].
Anditixafortide (Pentixather) is an endoradiotherapeutic vector. Anditixafortide is a CXCR4-targeting peptide derivative[1].
Experimental allergic encephalitogenic peptide (human) is a EAE peptide. Experimental allergic encephalitogenic peptide (human) induces encephalomyelitis in guinea pigs[1].
Fluorescein-O-acetate is a fluorescent reagent[1].
3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum[1].
Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana[1].
1-Bromoheptane-d5 is the deuterium labeled 1-Bromoheptane[1].
Ethyl 3-hydroxy-3-methylbutanoate-d6 is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].
Lonchocarpic acid has an anti-inflammatory mechanism of lonchocarpine in LPS- or poly(I:C)-induced neuroinflammation[1].
2,4-DA-6-FP is a hapten and MR1 ligand. 2,4-DA-6-FP can used in study autoimmune diseases and cancers[1].