3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative.
Bakkenolide D is the main component of bakkenolide in Petasites tricholobus. Bakkenolide has anti-allergic effects and can be used in the study of allergic rhinitis[1].
Cholesteryl n-valerate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Deacylmetaplexigenin is a pregnane glycoside isolated from Asclepias incarnate[1].
N-Trimethylchitosan is a water-soluble multifunctional polymer which is a Chitosan (HY-B2144A) derivative. N-Trimethylchitosan can be used for drug delivery and to synthesize nanoparticles[1].
FHND5071 is a potent and selective RET kinase inhibitor, FHND5071 can exert antitumor effects by inhibiting RET autophosphorylation. FHND5071 can be used for tumor diseases research[1].
Condurango glycoside E3 (Compound 5) is a pregnanate glycoside derived from the dry bark of Marsdenia cundurango[1].
Prucalopride succinate is a selective, high affinity 5-HT4 receptor agonist with pKi of 8.6/8.1 for 5-HT4a/4b.IC50 value:Target: 5-HT4 agonistin vitro: Prucalopride was a 5-HT(4) receptor agonist in the guinea-pig colon, as it induced contractions (pEC(50)=7.48+/-0.06; insensitive to a 5-HT(2A) or 5-HT(3) receptor antagonist, but inhibited by a 5-HT(4) receptor antagonist) as well as the facilitation of electrical stimulation-induced noncholinergic contractions (blocked by a 5-HT(4) receptor antagonist). Prucalopride did not cause relevant inhibition of 5-HT(2A), 5-HT(2B), or 5-HT(3), motilin or cholecystokinin (CCK(1)) receptor-mediated contractions, nor nicotinic or muscarinic acetylcholine receptor-mediated contractions, up to 10 microM [1].in vivo: Rat microdialysis studies revealed that prucalopride maximally increased ACh and histamine levels in the prefrontal cortex at 5 and 10 mg/kg, whereas PRX-03140 significantly increased cortical histamine levels at 50 mg/kg, failing to affect ACh release at doses lower than 150 mg/kg [2].
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.
Yuanhuanin is a natural product that originally recognized in D. sericea. Yuanhuanin also can be isolated also from D. koreana and D. pedunculata[1].
ATTO 488 iodacetamid is a fluorescent dye suitable for single molecule detection applications and high-resolution microscopy for use in flow cytometry (FACS), fluorescence in situ hybridization (FISH) experiments. ATTO 488 iodacetamid has an effective excitation wavelength of 480-515 nm. When using an argon ion laser, the excitation wavelength is recommended to be 488 nm.
Emoxypine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
L-Inosine is the L-configuration of Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects[1][2].
2,3-Dimethyl-D-valine is a valine derivative[1].
6-Hepten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
2-Hydroxy4,7-dimethoxy-9,10-dihydrophenanthrene is a natural product, isolated from the stem of Dendrobium nobile[1].
alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation，In vitro: a-hederin is cytotoxic and inhibits proliferation in bothcel lines at rather low concentrations. , a-hederin reduces themitotic activity in treated cels.[1]In vivo: alpha-hederin had preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses. [2]
3’-Amino-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex[1][2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells[3].
Hentriacontanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Allyl Nonanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Stearic anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Trioctylamine-d6 is the deuterium labeled Trioctylamine[1].
Officinalisnin-II is a natural saponin found in the roots of Asparagus filicinus[1].
DPyPE is a phosphatidylethanolamine lipid composed of polyisoprene alkyl chains. DPyPE is a co-lipid forvaxfectin mixed with GAP-DMORIE in a 1:1 ratio[1].
7β-O-Methylmorroniside (7R-O-methylmorroniside) is a R-isomer of 7-O-Methyl morroniside[1].
Sodium (S)-2-hydroxypropanoate (Sodium L-lactate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid[1].
1-O-Dodecyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].
hCAI/II-IN-4 (compound 6d) is a potent dual hCA I/II inhibitor with Ki values of 16.95, 15.22 and 27.04 nM for hCA I, hCA II and hCA Ⅸ, respectively. hCAI/II-IN-4 has anti-hypoxia activities and low toxicity. hCAI/II-IN-4 can be used for acute mountain sickness (AMS) research[1].