Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2-(Pyren-1-ylaminocarbonyl)ethyl Methanethiosulfonate

2-(Pyren-1-ylaminocarbonyl)ethyl methanethiosulfonate is a fluorescent[1].

  • CAS Number: 384342-64-7
  • MF: C20H17NO3S2
  • MW: 383.48400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 171-173ºC
  • Flash Point: N/A

N'-Cbz-L-lysine tert-butyl ester hydrochloride

H-Lys(Z)-OtBu.HCl is a lysine derivative[1].

  • CAS Number: 5978-22-3
  • MF: C18H29ClN2O4
  • MW: 372.887
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 469.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.8ºC

3’-Deoxy-3’-fluoro-5-methyluridine

3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 125217-37-0
  • MF: C10H13FN2O5
  • MW: 260.22
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-β-Ala-Gly-β-Ala-OH

Ala-Gly-Ala is a prototype of a general tripeptide Xxx-Gly-Zzz. Except glycine and proline, there can be 18 possible amino acids for Xxx and another 18 amino acids for Zzz. Ala-Gly-Ala can be used as a model for up to 324 possible motifs of this kind of tripeptide[1].

  • CAS Number: 37460-22-3
  • MF: C8H15N3O4
  • MW: 217.22200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl Lauroyl Arginate Hydrochloride

Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative[1].

  • CAS Number: 60372-77-2
  • MF: C20H41ClN4O3
  • MW: 421.017
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 57-61°C
  • Flash Point: N/A

Resazurin sodium salt

Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

  • CAS Number: 62758-13-8
  • MF: C12H6NNaO4
  • MW: 251.170
  • Catalog: Biochemical Assay Reagents
  • Density: N/A
  • Boiling Point: 477.2ºC at 760 mmHg
  • Melting Point: >200ºC
  • Flash Point: 242.4ºC

Boc-MePhe-OH·DCHA

Boc-N-Me-Phe DCHA is a phenylalanine derivative[1].

  • CAS Number: 40163-88-0
  • MF: C27H44N2O4
  • MW: 460.649
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 587.7ºC at 760 mmHg
  • Melting Point: 174-177ºC
  • Flash Point: 309.2ºC

PSB 1114

PSB-1114 tetrasodium is a potent, enzymatically stable, and subtype-selective P2Y2 receptor agonist with an EC50 of 134 nM. PSB-1114 tetrasodium displays >50-fold selectivity versus the P2Y4 (EC50 of 9.3 μM) and P2Y6 (EC50 of 7.0 μM) receptors[1].

  • CAS Number: 1657025-60-9
  • MF: C10H11F2N2Na4O13P3S
  • MW: 622.14
  • Catalog: P2Y Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Chg-OH

(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 109183-71-3
  • MF: C13H23NO4
  • MW: 257.326
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 407.9±28.0 °C at 760 mmHg
  • Melting Point: 83 °C
  • Flash Point: 200.5±24.0 °C

5(6)-Aminofluorescein

5(6)-Aminofluorescein is a high purity and quality chemical used as molecular probe and important as fluorescent agent.

  • CAS Number: 27599-63-9
  • MF: C20H13NO5
  • MW: 347.321
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 695.3±55.0 °C at 760 mmHg
  • Melting Point: 223ºC (dec.)(lit.)
  • Flash Point: 374.3±31.5 °C

SK-MLCK M13

SK-MLCK M13 is a biological active peptide. (M-13 is a peptide that represents CAM-binding domain of Calmodulin (CaM) target proteins. CaM is an ubiquitous Ca2+ binding protein.)

  • CAS Number: 99268-57-2
  • MF: C134H223N43O33
  • MW: 2964.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-octaguluronic acid octasodium salt

L-octaguluronic acid octasodium salt is extracted from seaweed. L-octaguluronic acid octasodium salt is the component of the natural biopolymers, alginates[1][2].

  • CAS Number: 862694-88-0
  • MF: C48H58Na8O49
  • MW: 1602.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Methyl(2H)formamide

N-Methylformamide-d1 is the deuterium labeled N-Methylformamide[1].

  • CAS Number: 26103-38-8
  • MF: C2H4DNO
  • MW: 60.073
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 182.5±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 81.5±3.7 °C

L-Valine-13C5,15N

L-Valine-13C5,15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].

  • CAS Number: 202407-30-5
  • MF: 13C5H1115NO2
  • MW: 123.10300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ezetimibe D4

Ezetimibe D4 (SCH 58235 D4) is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

  • CAS Number: 1093659-90-5
  • MF: C24H17D4F2NO3
  • MW: 413.450
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 654.9±55.0 °C at 760 mmHg
  • Melting Point: 152-154°C
  • Flash Point: 349.9±31.5 °C

GENZ-882706(Raceme)

GENZ-882706(Raceme) is the racemate of GENZ-882706.

  • CAS Number: 2070861-46-8
  • MF: C26H25N5O3
  • MW: 455.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eupatorin-5-methylether

Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

  • CAS Number: 21764-09-0
  • MF: C19H18O7
  • MW: 358.34200
  • Catalog: Others
  • Density: 1.309g/cm3
  • Boiling Point: 573.7ºC at 760mmHg
  • Melting Point: 179-180ºC
  • Flash Point: 207.4ºC

Sucrose stearate

Sucrose Stearate can be used as an excipient, such as Surfactants, emulsifiers, solubilizers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 25168-73-4
  • MF: C30H56O12
  • MW: 608.758
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 763.2±60.0 °C at 760 mmHg
  • Melting Point: 67-71°C (lit.)
  • Flash Point: 235.6±26.4 °C

(S)-Methyl 2-((Tert-Butoxycarbonyl)Amino)-3-(3,4-Dihydroxyphenyl)Propanoate

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate is a tyrosine derivative[1].

  • CAS Number: 37169-36-1
  • MF: C15H21NO6
  • MW: 311.33000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Feruloyl esterase

Feruloyl esterase plays a major role in the degradation of plant biomass. Feruloyl esterase catalyzes the cleavage and formation of ester bonds between plant cell wall polysaccharide and phenolic acid[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydroxy ipronidazole

Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound[1].

  • CAS Number: 35175-14-5
  • MF: C7H11N3O3
  • MW: 185.18100
  • Catalog: Others
  • Density: 1.34 g/cm3
  • Boiling Point: 367.7ºC at 760 mmHg
  • Melting Point: 108-110°C
  • Flash Point: 176.2ºC

Dihydromethysticin

Dihydromethysticin is one of the six major kavalactones found in the kava plant; has marked activity on the induction of CYP3A23.

  • CAS Number: 19902-91-1
  • MF: C15H16O5
  • MW: 276.284
  • Catalog: Cytochrome P450
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 476.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 214.1±28.8 °C

tos-pro-oh

Tos-Pro-OH is a proline derivative[1].

  • CAS Number: 51077-01-1
  • MF: C12H15NO4S
  • MW: 269.31700
  • Catalog: Others
  • Density: 1.377g/cm3
  • Boiling Point: 467.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 236.6ºC

Pyr-Gly-OH

Pyr-Gly is an inhibitory peptide. Pyr-Gly inhibits proliferation of retinal pigment epithelium (RPE) cells and fibroblasts[1].

  • CAS Number: 29227-88-1
  • MF: C7H10N2O4
  • MW: 186.17
  • Catalog: Others
  • Density: 1.405g/cm3
  • Boiling Point: 659.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 352.5ºC

Scillascillone

Scillascillone is a lanostane-type triterpenoid, which can be isolated from the whole plants of Scilla scilloides[1].

  • CAS Number: 2023822-40-2
  • MF: C30H44O6
  • MW: 500.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Deoxycorticosterone-d8

Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

  • CAS Number: 55487-63-3
  • MF: C21H22D8O3
  • MW: 338.510
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 488.0±45.0 °C at 760 mmHg
  • Melting Point: 132-134ºC
  • Flash Point: 263.0±25.2 °C

Urotensin II (goby)

Urotensin II, teleost fish is a cyclic peptide. It can be isolated from the caudal neurosecretory system of teleost fish[1].

  • CAS Number: 9047-55-6
  • MF: C62H84N14O17S2
  • MW: 1361.54000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oxadiazon

Oxadiazon is a preemergent herbicide.

  • CAS Number: 19666-30-9
  • MF: C15H18Cl2N2O3
  • MW: 345.221
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 417.0±55.0 °C at 760 mmHg
  • Melting Point: 88-90°C
  • Flash Point: 206.0±31.5 °C

3’-O-(2-Methoxyethyl)guanosine

3’-O-(2-Methoxyethyl)guanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

  • CAS Number: 256224-03-0
  • MF: C13H19N5O6
  • MW: 341.32
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Delcorine

Delcorine is a C19-diterpenoid alkaloid, which can be isolated from the whole herb of Delphinium anthriscifolium var. savatieri[1].

  • CAS Number: 52358-55-1
  • MF: C26H41NO7
  • MW: 479.60600
  • Catalog: Others
  • Density: 1.29g/cm3
  • Boiling Point: 586.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 308.5ºC