Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Bursin (avian)

Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi[1].

  • CAS Number: 60267-34-7
  • MF: C14H25N7O3
  • MW: 339.39300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate

2'-Deoxyadenosine monohydrate-13C10,15N5 (hydrate) is the 13C and 15N labeled 2'-Deoxyadenosine monohydrate[1]. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.

  • CAS Number: 2483830-27-7
  • MF: 13C10H1515N5O4
  • MW: 284.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 2-hydroxy-4-methylvalerate

Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota[1].

  • CAS Number: 40348-72-9
  • MF: C7H14O3
  • MW: 146.18400
  • Catalog: Others
  • Density: 1.002 ± 0.06 g/cm3
  • Boiling Point: 72 (10 mm Hg),181.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 150.00 °F. TCC ( 65.56ºC. )

2'-O-Methyluridine

2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota[1].

  • CAS Number: 2140-76-3
  • MF: C10H14N2O6
  • MW: 258.228
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 154-156ºC
  • Flash Point: N/A

Protein Kinase C γ Peptide

Protein Kinase C (gamma) Peptide is a peptide fragment of Protein Kinase Cγ. Protein Kinase Cγ is a protein causative for dominant ataxia, that can negatively regulate nuclear import of recessive-ataxia-related aprataxin[1].

  • CAS Number: 309247-51-6
  • MF: C75H117N21O23S
  • MW: 1712.92
  • Catalog: PKC
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lercanidipine. (R)-

Lercanidipine. (R)- is an enantiomer of antihypertensive drugs Lercanidipine. Lercanidipine acts by blocking L-type calcium channels, allowing relaxation and opening of blood vessels.

  • CAS Number: 185197-70-0
  • MF: C36H41N3O6
  • MW: 611.73
  • Catalog: Calcium Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SMI481

NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14[1].

  • CAS Number: 432020-20-7
  • MF: C17H15ClFN3O3
  • MW: 363.771
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 543.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 282.4±30.1 °C

H-Phe-Phe-Phe-Phe-Phe-OH

H-Phe-Phe-Phe-Phe-Phe-OH has a self-assembled structure, which can be assembled into an ordered autofluorescent elongated structure, showing mechanochromic properties[1].

  • CAS Number: 65757-10-0
  • MF: C45H47N5O6
  • MW: 753.88
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Epimedonin B

Epimedonin B is a 2-phenoxychromone that can be isolated from Epimedium koreanum[1].

  • CAS Number: 1616061-69-8
  • MF: C20H16O6
  • MW: 352.337
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 570.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.9±23.6 °C

Complanatoside A

Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.

  • CAS Number: 146501-37-3
  • MF: C27H30O18
  • MW: 642.52
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 975.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 320.2±27.8 °C

Tetradecylamine-d29

Tetradecylamine-d29 is the deuterium labeled Tetradecylamine[1].

  • CAS Number: 204244-82-6
  • MF: C14H2D29N
  • MW: 242.58100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

h-NTPDase-IN-3

h-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).

  • CAS Number: 2939933-10-3
  • MF: C16H10N4S
  • MW: 290.34
  • Catalog: Phosphatase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Carbamazepine 10,11-epoxide-13C-1

Carbamazepine 10,11-epoxide-13C-1 is the 13C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

  • CAS Number: 1374855-73-8
  • MF: C1413CH12N2O2
  • MW: 253.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GGASCCLYCRCH

GGASCCLYCRCH is a biological active peptide. (can inhibit the 2-O-methyltransferase activity of the SARS-CoV complex nsp16/10)

  • CAS Number: 1401180-68-4
  • MF: C49H77N17O15S4
  • MW: 1272.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Didehydrosomnifericin

2,3-Didehydrosomnifericin is one of withanolides found in Withania somnifera[1].

  • CAS Number: 173614-88-5
  • MF: C28H40O7
  • MW: 488.61
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 677.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 222.2±25.0 °C

Camelliaside B

Camelliaside B is a flavonoid from the methanol extract of tea (Camellia oleifera) seed pomace[1].

  • CAS Number: 131573-90-5
  • MF: C32H38O19
  • MW: 726.633
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 1058.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 336.2±27.8 °C

Hancinone C

Hancinone C (compound 2) is a natural product that can be found in Piper hancei[1].

  • CAS Number: 111843-10-8
  • MF: C23H28O6
  • MW: 400.46
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 550.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 237.4±30.2 °C

[18F]AZD4694 Precursor

[18F]AZD4694 Precursor is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques[1].

  • CAS Number: 1211333-20-8
  • MF: C22H25N3O7
  • MW: 443.45
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 593.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 312.7±30.1 °C

Fmoc-Phe

Fmoc-DL-Phe-OH is a phenylalanine derivative[1].

  • CAS Number: 126727-04-6
  • MF: C24H21NO4
  • MW: 387.428
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 620.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 328.8±30.1 °C

7,4'-Dihydroxyhomoisoflavane

7,4'-Dihydroxyhomoisoflavane is a natural antioxidant. 7,4'-Dihydroxyhomoisoflavane has ABTS radical-scavenging capacity with an IC50 of 0.22 mg/mL[1].

  • CAS Number: 148462-00-4
  • MF: C16H16O3
  • MW: 256.3
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite

DMT-2'O-MOE-rG(ib) Phosphoramidite (1g), belonging to the amide family of trivalent phosphate H3PO3, is a derivative of nucleotides and guanosine and can be used in the stereochemical synthesis of phosphorothioate oligonucleotides[1].

  • CAS Number: 251647-55-9
  • MF: C47H60N7O10P
  • MW: 913.99400
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2H10)-1,2-Dihydroacenaphthylene

Acenaphthene-d10 is the deuterium labeled Acenaphthene[1].

  • CAS Number: 15067-26-2
  • MF: C12D10
  • MW: 164.269
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 279.0±0.0 °C at 760 mmHg
  • Melting Point: 95-97ºC(lit.)
  • Flash Point: 135.3±9.7 °C

((3-Fluorophenyl)sulfonyl)-L-methionine

((3-Fluorophenyl)sulfonyl)-L-methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 1240429-16-6
  • MF: C11H14FNO4S2
  • MW: 307.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zearalenone-13C18

Zearalenone-13C18 (Mycotoxin F2-13C18; Toxin F2-13C18) is the 13C labeled Zearalenone (HY-103447)[1]. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts[2][3].

  • CAS Number: 911392-43-3
  • MF: 13C18H22O5
  • MW: 336.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: 2℃

Ophiopogonanone E

Ophiopogonanone E is a homoisoflavonoid, that can be isolated from the fibrous roots of Polygonatum odoratum[1].

  • CAS Number: 588706-66-5
  • MF: C19H20O7
  • MW: 360.36
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 620.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 224.9±25.0 °C

tolazoline

Tolazoline(NSC35110; Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.IC50 value:Target: α-adrenoceptor antagonistTolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of tolazoline is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics.

  • CAS Number: 59-98-3
  • MF: C10H12N2
  • MW: 160.216
  • Catalog: Adrenergic Receptor
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 338.2±21.0 °C at 760 mmHg
  • Melting Point: 66-69 °C(lit.)
  • Flash Point: 158.3±22.1 °C

Boc-L-4-Trifluoromethylphe

(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 114873-07-3
  • MF: C15H18F3NO4
  • MW: 333.303
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 431.4±45.0 °C at 760 mmHg
  • Melting Point: 118-137ºC
  • Flash Point: 214.7±28.7 °C

4,5-Dihydroblumenol A

4,5-Dihydroblumenol A is a norisoprenoid, that can be isolated from Pavonia multiflora A. ST-HIL. (Malvaceae)[1].

  • CAS Number: 155418-97-6
  • MF: C13H22O3
  • MW: 226.31
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 345.7±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.1±24.4 °C

Benzyldimethylstearylammonium chloride

Benzyldimethylstearylammonium chloride, a quarternary ammonium compound, exerts no selective embryopathic activity[1].

  • CAS Number: 122-19-0
  • MF: C27H50ClN
  • MW: 424.146
  • Catalog: Others
  • Density: 0.98
  • Boiling Point: 100ºC
  • Melting Point: 54-56ºC
  • Flash Point: 94ºC

Stenophyllol B

Stenophyllol B (compound 4) is a trimeric stilbene with bicyclic and bridged tricyclic skeletons. Stenophyllol B was first discovered in the dipterocarps plant and has been found in many species of Hopea, Neobalanocarpus, Shorea, Stemonoporus and Vateri[1].

  • CAS Number: 208834-81-5
  • MF: C42H32O9
  • MW: 680.7
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A