Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Tetrachloroveratrole

Tetrachloroveratrole is one of the biodegradation products of bacterial O-methylation of Tri- and Tetra chloroguaiacols. The Tri- and Tetra chloroguaiacols are formed during bleaching of wood pulp in the paper manufacturing industry[1].

  • CAS Number: 944-61-6
  • MF: C8H6Cl4O2
  • MW: 275.94400
  • Catalog: Others
  • Density: 1.489g/cm3
  • Boiling Point: 318.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 122.1ºC

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a polypeptide compound containing sulfamide, can be used to synthesis peptide-drug coupling compounds[1].

  • CAS Number: 128421-85-2
  • MF: C17H24N2O4S
  • MW: 352.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12-Deoxo-12α-acetoxyelliptone

12-Deoxo-12α-acetoxyelliptone is a compound isolated from the roots of Derris oblonga[1].

  • CAS Number: 150226-21-4
  • MF: C22H20O7
  • MW: 396.39
  • Catalog: Others
  • Density: 1.4±0.0 g/cm3
  • Boiling Point: 489.4±0.0 °C at 760 mmHg
  • Melting Point: 150-152 °C
  • Flash Point: 249.8±0.0 °C

Palmitoyl pentapeptide-4

Palmitoyl pentapeptide 4 (Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide) is a bioactive peptide with anti-ageing effect and has been reported used as a cosmetic ingredient[1]

  • CAS Number: 214047-00-4
  • MF: C39H75N7O10
  • MW: 802.054
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 1120.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 631.2±34.3 °C

nicotinoyl azide

Nicotinoyl azide is capable of forming high energy intermediates known to form C-8 adducts with adenosine and guanosine[1].

  • CAS Number: 4013-72-3
  • MF: C6H4N4O
  • MW: 148.12200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 77298-67-0
  • MF: C21H20O12
  • MW: 464.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gibberellic acid-d2

Gibberellic acid-d2 is the deuterium labeled Gibberellic acid. Gibberellic acid is named after a fungus Gibberella fujikuroi. Gibberellic Acid regulates processes of plant development and growth, including seed development and germination, stem and root growth, cell division, and flowering time[1][2].

  • CAS Number: 120396-36-3
  • MF: C19H20D2O6
  • MW: 348.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Formyl-L-leucine

N-Formyl-L-leucine is a leucine derivative[1].

  • CAS Number: 6113-61-7
  • MF: C7H13NO3
  • MW: 159.183
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 360.6±25.0 °C at 760 mmHg
  • Melting Point: 142 °C
  • Flash Point: 171.9±23.2 °C

4H-Pyrrolo[3,2-d]pyrimidin-4-one,2-amino-3,5-dihydro

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP)[1].

  • CAS Number: 65996-58-9
  • MF: C6H6N4O
  • MW: 150.14
  • Catalog: Others
  • Density: 1.87g/cm3
  • Boiling Point: 452.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 227.6ºC

Hydroxytyrosol acetate

Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol[1].

  • CAS Number: 69039-02-7
  • MF: C10H12O4
  • MW: 196.200
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 355.9±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 141.6±17.2 °C

8-Nonen-1-ol

8-Nonen-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 13038-21-6
  • MF: C9H18O
  • MW: 142.239
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 197.9±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 79.0±10.4 °C

Biotin-C5-Azide

Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates.

  • CAS Number: 1260586-88-6
  • MF: C10H17N5OS
  • MW: 255.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n(alpha) n-(im)-di-boc-l-histidine

N(α), N-(im)-Di-Boc-L-histidine methyl ester is a histidine derivative[1].

  • CAS Number: 17791-51-4
  • MF: C17H27N3O6
  • MW: 369.41300
  • Catalog: Others
  • Density: 1.17g/cm3
  • Boiling Point: N/A
  • Melting Point: 113-116ºC(lit.)
  • Flash Point: N/A

picropodophyllol

Picropodophyllol is a triol[1].

  • CAS Number: 3811-15-2
  • MF: C22H26O8
  • MW: 418.44
  • Catalog: Others
  • Density: 1.316±0.06 g/cm3 at 760 mmHg
  • Boiling Point: 592.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Ethylene brassylate

1,4-Dioxacycloheptadecane-5,17-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 105-95-3
  • MF: C15H26O4
  • MW: 270.365
  • Catalog: Others
  • Density: 1.042
  • Boiling Point: 476.1±28.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 243.9±22.4 °C

LL-37 RKS trifluoroacetate salt

LL-37 RKS is an active fragment of LL-37[1].

  • CAS Number: 672345-61-8
  • MF: C169H292N54O45
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Cyclopropyl-4-iodobenzamide

N-Cyclopropyl-4-iodobenzamide is an active molecule.

  • CAS Number: 794539-14-3
  • MF: C10H10INO
  • MW: 287.09697
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 389.9±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.6±23.2 °C

7-cyano-7-deazaguanosine

7-Cyano-7-deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 61210-21-7
  • MF: C12H13N5O5
  • MW: 307.26
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cycloastragenol

Cycloastragenol, a natural tetracyclic triterpenoid, was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties. IC50 value:Target:In vitro: In the study of Cycloastragenolon the treatment of degenerative diseases, the result showed that first-pass intestinal metabolism of cycloastragenol might occur upon passage through the intestinal epithelium. Cycloastragenol underwent extensive metabolism in rat and human liver microsomes with only 17.4% and 8.2%, respectively, of the starting amount of Cycloastragenol remaining after 30 min of incubation [1]. The present study demonstrates that cycloastragenol stimulates telomerase activity and cell proliferation in human neonatal keratinocytes. In particular, cycloastragenol promotes scratch wound closure of human neonatal keratinocyte monolayers in vitro [3]. In vivo: Rats were treated with Cycloastragenol (40 mg·kg- 1·d- 1) for 7 days to induce hepatic microsomal enzyme. The result showed that compared with the control, cycloastragenol obviously activated CYP2E1, and remarkably inhibited CYP3A4 [2].

  • CAS Number: 84605-18-5
  • MF: C30H50O5
  • MW: 490.715
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 617.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.1±31.5 °C

3-(Hexadecyloxy)-2-methoxy-1-propanol

1-O-hexadecyl-2-O-methyl-sn-glycerol (PMG) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 96960-92-8
  • MF: C20H42O3
  • MW: 330.546
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 430.6±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 214.2±23.2 °C

Cyanidin-3-O-arabinoside chloride

Cyanidin-3-O-arabinoside is a pigment isolated from flowers of Rhododendron cv. Lems Stormcloud[1].

  • CAS Number: 111613-04-8
  • MF: C20H19ClO10
  • MW: 454.81
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

STIMA 1

STIMA-1 is an active compound. STIMA-1 can restore the activity of p63. STIMA-1 can activate the proliferation and differentiation of keratinocytes[1].

  • CAS Number: 91634-12-7
  • MF: C10H8N2O
  • MW: 172.18300
  • Catalog: Others
  • Density: 1.2 g/cm3
  • Boiling Point: 315.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 144.5ºC

Linderanine C

Linderanine C ((-)-Linderanine C) (compound 6) is a sesquiterpenoid compound that can be isolated from the roots of Wuyao[1].

  • CAS Number: 139681-96-2
  • MF: C15H16O5
  • MW: 276.28
  • Catalog: Others
  • Density: 1.36±0.1 g/cm3(Predicted)
  • Boiling Point: 536.0±50.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

umuhengerin

Umuhengerin is a methoxylated flavone. Umuhengerin can be isolated from Cardiospermum corindum L[1].

  • CAS Number: 29215-55-2
  • MF: C20H20O8
  • MW: 388.36800
  • Catalog: Others
  • Density: 1.304g/cm3
  • Boiling Point: 581.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 205.9ºC

Anti-osteoporosis agent-7

Anti-osteoporosis agent-7 (Compound 133) is a potential anti-osteoporosis agent showing high inhibition of osteoclast formation.

  • CAS Number: 445254-59-1
  • MF: C18H19Cl2NO3
  • MW: 368.25
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 514.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.9±30.1 °C

b-Chlorophyll

Chlorophyll b is decomposed by chlorophyllase to form pheophytin b. This causes its color to change from green to olive brown. It is involved in the harvesting of light energy and its subsequent conversion into chemical energy during photosynthesis. Along with chlorophyll a, it plays a key role in the ability of plants to adapt to varying light intensities. The visible spectrum that is not absorbed when only chlorophyll a is present in the LHC.

  • CAS Number: 519-62-0
  • MF: C55H70MgN4O6
  • MW: 907.472
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 1071.6ºC at 760mmHg
  • Melting Point: 183-185ºC(lit.)
  • Flash Point: 601.9ºC

Trifludimoxazin

Trifludimoxazin is a protoporphyrinogen oxidase inhibiting (PPO) herbicide[1].

  • CAS Number: 1258836-72-4
  • MF: C16H11F3N4O4S
  • MW: 412.34300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Atisnolerbart

Atisnolerbart is a human IgG4 antibody targeting BETVIA, the major birch pollen allergen Bet v 1-A.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 327178-94-9
  • MF: C38H11D62NNaO10P
  • MW: 820.333
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-4-fluorophenoxy]ethoxy]-5-fluoroanilino]acetate

5,5'-Difluoro BAPTA is the most widely used probe for studying cytosolic free Ca2+ by 19F NMR. 5,5'-Difluoro BAPTA has high selectivity for Ca2+. 5,5'-Difluoro BAPTA can inhibit the growth of pollen tube[1][2].

  • CAS Number: 156027-00-8
  • MF: C34H38F2N2O18
  • MW: 800.66500
  • Catalog: Others
  • Density: 1.393g/cm3
  • Boiling Point: 799.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 437.6ºC