Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Kainic acid

Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.

  • CAS Number: 487-79-6
  • MF: C10H15NO4
  • MW: 213.230
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 439.9±45.0 °C at 760 mmHg
  • Melting Point: 253-254ºC
  • Flash Point: 219.8±28.7 °C

Vaxfectin

Vaxfectin is a cationic lipid-based adjuvant that can be used for plasmid DNA- and protein-based vaccines[1].

  • CAS Number: 370108-99-9
  • MF: C81H163BrN3O10P
  • MW: 1450.05
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-one

Umbelliprenin (compound 2) can be isolated from the chloroform extract of the roots of Heptaptera cilicica[1].

  • CAS Number: 23838-17-7
  • MF: C24H30O3
  • MW: 366.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bakkenolide B

Bakkenolide B is isolated from petasites japonicas leaves and has anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1].

  • CAS Number: 18455-98-6
  • MF: C22H30O6
  • MW: 390.470
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 503.0±50.0 °C at 760 mmHg
  • Melting Point: 101-102 °C
  • Flash Point: 217.1±30.2 °C

GPR132 antagonist 1

GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 μM[1].

  • CAS Number: 898211-21-7
  • MF: C18H17NO5S
  • MW: 359.40
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CIA-1 hcl(452087-38-6 Free base)

CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.

  • CAS Number: 1049691-47-5
  • MF: C17H20ClN3O2S
  • MW: 365.88
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ocean Blue, SE

PB succiniMidyl ester (Ocean Blue, SE) is a blue fluorescent dye, conjugates of this dye are strongly fluorescent even at neutral pH (λExcitation/emission~405/455 nm).

  • CAS Number: 215868-33-0
  • MF: C14H7F2NO7
  • MW: 339.20500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pp60 c-src (521-533) (phosphorylated) trifluoroacetate salt

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527[1].

  • CAS Number: 149299-77-4
  • MF: C62H95N16O28P
  • MW: 1543.48000
  • Catalog: Others
  • Density: 1.461 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Negsehisandrin G

Angeloyl-(+)-gomisin K3 is a dibenzocyclooctane lignan[1].

  • CAS Number: 1023744-69-5
  • MF: C28H36O7
  • MW: 484.581
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 625.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.5±31.5 °C

FTO-IN-8

FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity[1].

  • CAS Number: 2640366-38-5
  • MF: C19H23ClN2O2
  • MW: 346.85
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

UNII:841B886EJ7

DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, liposomes and other types of artificial membranes[1].

  • CAS Number: 200880-41-7
  • MF: C38H74NaO10P
  • MW: 744.952
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyrimidine,2,4-bis(1-aziridinyl)-6-chloro

Ethimidine (Aethimidinum) can reduce the blood serum free SH (sulfhydryl) in in rats previously transplanted with sarcoma or carcinoma cells[1].

  • CAS Number: 2482-80-6
  • MF: C8H9ClN4
  • MW: 196.63700
  • Catalog: Cancer
  • Density: 1.561g/cm3
  • Boiling Point: 410.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 202ºC

cis-Vaccenic acid

cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate[1], acts a potential fetal hemoglobin inducer[2].

  • CAS Number: 506-17-2
  • MF: C18H34O2
  • MW: 282.461
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 398.2±11.0 °C at 760 mmHg
  • Melting Point: 14-15ºC(lit.)
  • Flash Point: 295.0±14.4 °C

Cedrusin

Cedrusin is a benzofuran derivative that can be isolated from Styrax suberifolius[1].

  • CAS Number: 75775-36-9
  • MF: C19H22O6
  • MW: 346.37
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 558.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 291.3±30.1 °C

[Ala2] Met-Enkephalinamide

[Ala2] Met-Enkephalinamide is an active peptide. [Ala2] Met-Enkephalinamide can be used for the research of various biochemical studies[1].

  • CAS Number: 64240-07-9
  • MF: C28H38N6O6S
  • MW: 586.70
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Dimethylpyridine-d9

2,3-Dimethylpyridine-d9 is the deuterium labeled 2,3-Dimethylpyridine[1].

  • CAS Number: 350818-65-4
  • MF: C7H9N
  • MW: 107.153
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 160.7±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 45.4±7.9 °C

Sclareol glycol

Sclareol glycol is the precursor of ambroxide. Hyphozyma roseonigra ATCC 20624 was the only reported strain capable of degrading sclareol to the main product of sclareol glycol[1].

  • CAS Number: 55881-96-4
  • MF: C16H30O2
  • MW: 254.408
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 315.3±10.0 °C at 760 mmHg
  • Melting Point: 131-132ºC
  • Flash Point: 132.8±13.6 °C

Alpha-ketoisocaproic acid-13C2 sodium

Alpha-ketoisocaproic acid-13C2 (sodium) is the 13C labeled Alpha-ketoisocaproic acid sodium[1].

  • CAS Number: 2483736-09-8
  • MF: C413C2H10NaO3
  • MW: 155.12
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Bis(2-hydroxypropyl)nitrosamine

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.

  • CAS Number: 53609-64-6
  • MF: C6H14N2O3
  • MW: 162.187
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 352.4±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.9±23.7 °C

A 1120

A 1120 is a high affinity non-retinoid ligand for retinol-binding protein 4 (RBP4) with the ki value of 8.3 nM[1].

  • CAS Number: 1152782-19-8
  • MF: C20H19F3N2O3
  • MW: 392.37
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)glycine

((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 612043-42-2
  • MF: C9H7ClF3NO4S
  • MW: 317.66900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fosdenopterin

Fosdenopterin (Precursor Z) is a synthetic cyclic pyranopterin monophosphate (cPMP). Fosdenopterin can be used for the research of molybdenum cofactor deficiency (MoCD) type A[1].

  • CAS Number: 150829-29-1
  • MF: C10H14N5O8P
  • MW: 363.22
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S07-2008

S07-2008 is a selective aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 0.16 μM. S07-2008 shows anticancer activities[1].

  • CAS Number: 1090816-80-0
  • MF: C21H23N3O5S
  • MW: 429.49
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lobelanine

Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].

  • CAS Number: 579-21-5
  • MF: C22H25NO2
  • MW: 335.43900
  • Catalog: Others
  • Density: 1.076g/cm3
  • Boiling Point: 476.4ºC at 760mmHg
  • Melting Point: 99°
  • Flash Point: 196.2ºC

Fmoc-D-2-Nal-OH

Fmoc-D-2-Nal-OH is an alanine derivative[1].

  • CAS Number: 138774-94-4
  • MF: C28H23NO4
  • MW: 437.487
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 690.7±50.0 °C at 760 mmHg
  • Melting Point: 191 °C
  • Flash Point: 371.6±30.1 °C

Importazole

Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.

  • CAS Number: 662163-81-7
  • MF: C20H22N4
  • MW: 318.415
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 516.8±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 266.3±27.9 °C

PNPG

PNPG(4-Nitrophenyl-β-D- glucopyranoside) is a chromogenic β-D-glucosidase substrate, producing a yellow solution upon cleavage.

  • CAS Number: 2492-87-7
  • MF: C12H15NO8
  • MW: 301.249
  • Catalog: Biochemical Assay Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 582.2±50.0 °C at 760 mmHg
  • Melting Point: 165-168 °C
  • Flash Point: 305.9±30.1 °C

Boc-O-(2-bromo-Cbz)-D-tyrosine

Boc-D-Tyr(2-Br-Z)-OH is a tyrosine derivative[1].

  • CAS Number: 81189-61-9
  • MF: C22H24BrNO7
  • MW: 494.332
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 634.9±55.0 °C at 760 mmHg
  • Melting Point: 90-95°C (lit.)
  • Flash Point: 337.8±31.5 °C

Sibrotuzumab

Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Lys(Me)3-OH Chloride

Fmoc-Lys(Me)3-OH Chloride is a lysine derivative[1].

  • CAS Number: 201004-29-7
  • MF: C24H31ClN2O4
  • MW: 446.967
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A