Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

De-4'-O-methylyangambin

De-4’-O-methylyangambin is a lignan that can be isolated from Z. armatum. lignans are reported to has anti-inflammatory activity[1].

  • CAS Number: 149250-48-6
  • MF: C23H28O8
  • MW: 432.46
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 573.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.8±30.1 °C

Z-VDVA-(DL-Asp)-FMK

Z-VDVA-(DL-Asp)-FMK is a Z-VDVAD-FMK derivative. Z-VDVAD-FMK (HY-P1008) is a special inhibitor of caspase-2[1].

  • CAS Number: 1926163-61-2
  • MF: C32H46FN5O11
  • MW: 695.733
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 980.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 546.5±34.3 °C

H-Glu-Tyr-Glu-OH

H-Glu-Tyr-Glu-OH is a biologically active peptide.

  • CAS Number: 32140-46-8
  • MF: C19H25N3O9
  • MW: 439.41700
  • Catalog: Others
  • Density: 1.451g/cm3
  • Boiling Point: 915.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 507.7ºC

Somatostatin-14 (reduced)

Somatostatin-14 (reduced) (SST 14) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 40958-31-4
  • MF: C76H106N18O19S2
  • MW: 1639.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thiamine diphosphate analog 1

Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate[1]. Thiamine diphosphate is the active form of vitamin B1. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways[2].

  • CAS Number: 2606-90-8
  • MF: C6H11NO7P2S
  • MW: 303.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diacetylpiptocarphol

Diacetylpiptocarphol (compound 4) is a sesquiterpene lactone compound. Diacetylpiptocarphol has anti-leishmaniasis activity [1].

  • CAS Number: 101628-29-9
  • MF: C19H24O9
  • MW: 396.39
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 572.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 201.5±23.6 °C

PAR-2 (6-1) amide (human) trifluoroacetate salt

VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells[1][2].

  • CAS Number: 942413-05-0
  • MF: C28H54N8O7
  • MW: 614.77800
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Resolvin D1 methyl ester

Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels[1].

  • CAS Number: 937738-63-1
  • MF: C23H34O5
  • MW: 390.513
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 562.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.4±23.6 °C

Tirnovetmab

Tirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hosenkoside G

Hosenkoside G, a baccharane glycoside isolated from the seeds of Impatiens Balsamina L., possesses anti-tumor activity[1][2].

  • CAS Number: 160896-46-8
  • MF: C47H80O19
  • MW: 949.127
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1044.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 585.5±34.3 °C

Avobenzone

Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.Target: OthersAvobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. It can degrade faster in light in combination with mineral UV absorbers like zinc oxide and titanium dioxide, though with the right coating of the mineral particles this reaction can be reduced. A manganese doped titanium dioxide may be better than undoped titanium dioxide to improve avobenzone's stability. It reacts with minerals to form colored complexes. Manufacturers of avobenzone, like DSM recommend to include a chelator to prevent this from happening. They also recommend to avoid the inclusion of iron and ferric salts, heavy metals, formaldehyde donors and PABA and PABA esters[1].

  • CAS Number: 70356-09-1
  • MF: C20H22O3
  • MW: 310.387
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 463.6±35.0 °C at 760 mmHg
  • Melting Point: 81-84 °C
  • Flash Point: 203.1±26.0 °C

H-Met-OMe.HCl

L-Methionine methyl ester hydrochloride is a Methionine (HY-13694) derivative[1].

  • CAS Number: 2491-18-1
  • MF: C6H14ClNO2S
  • MW: 199.699
  • Catalog: Others
  • Density: 1.094g/cm3
  • Boiling Point: 277.6ºC at 760 mmHg
  • Melting Point: 151-153 °C(lit.)
  • Flash Point: 121.7ºC

Kinetin triphosphate

Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research[1].

  • CAS Number: 1450894-16-2
  • MF: C15H20N5O14P3
  • MW: 587.27
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

9-Methoxycanthin-6-one

9-Methoxycanthin-6-one, a canthin-6-one alkaloid, is present in intact plant parts and in callus tissues of different explants. 9-Methoxycanthin-6-one shows anti-tumor activity[1][2].

  • CAS Number: 74991-91-6
  • MF: C15H10N2O2
  • MW: 250.25200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oil Red O

Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses[1].

  • CAS Number: 1320-06-5
  • MF: C26H24N4O
  • MW: 408.495
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 638.8±55.0 °C at 760 mmHg
  • Melting Point: 120ºC
  • Flash Point: 439.7±20.8 °C

2'-aminobenzanilide

2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade[1][2].

  • CAS Number: 4424-17-3
  • MF: C13H12N2O
  • MW: 212.24700
  • Catalog: Others
  • Density: 1.244 g/cm3
  • Boiling Point: 309.6ºC at 760 mmHg
  • Melting Point: 133-134°C
  • Flash Point: 141ºC

Syringaresil diacetate

DL-Syringaresinol diacetate is a glucoside. DL-Syringaresinol inhibits cAMP phosphodiesterase and alleviation of stress[1].

  • CAS Number: 1990-77-8
  • MF: C26H30O10
  • MW: 502.510
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 556.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 236.2±30.2 °C

Cnidilin

Cnidilin (Knidilin) is isolated from the root of Angelica dahurica[1].

  • CAS Number: 14348-22-2
  • MF: C17H16O5
  • MW: 300.306
  • Catalog: Others
  • Density: 1.243
  • Boiling Point: 480.4±45.0 °C at 760 mmHg
  • Melting Point: 117-118℃
  • Flash Point: 244.4±28.7 °C

12-(Azido)lauric acid

Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].

  • CAS Number: 80667-36-3
  • MF: C12H23N3O2
  • MW: 241.330
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganoderic acid I

Ganoderic acid I is a triterpenoid found in ganoderma lucidum[1].

  • CAS Number: 98665-20-4
  • MF: C30H44O8
  • MW: 532.67
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 725.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 406.7±29.4 °C

(S)-Lercanidipine D3 hydrochloride

(S)-Lercanidipine D3 (hydrochloride) is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an antihypertensive agent[1].

  • CAS Number: 1217740-02-7
  • MF: C36H39D3ClN3O6
  • MW: 651.21
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Thr(Bzl)-OH

BOC-O-Benzyl-L-threonine is a threonine derivative[1].

  • CAS Number: 15260-10-3
  • MF: C16H23NO5
  • MW: 309.358
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 461.5±45.0 °C at 760 mmHg
  • Melting Point: 112-114ºC
  • Flash Point: 232.9±28.7 °C

Compound 48/80

Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways[1][2].

  • CAS Number: 94724-12-6
  • MF: C32H45N3O3
  • MW: 519.72
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

beta-d-Glucan, (1->3),(1->6)

Odetiglucan, a novel beta glucan, is a potent immunostimulant. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Racotumomab

Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer[1][2][3].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetylursolic acid

Ursolic acid acetate (Acetylursolic acid), isolated from the aerial roots of Ficus microcarpa, exhibits cytotoxicity against KB cells with IC50 of 8.4 μM[1].

  • CAS Number: 7372-30-7
  • MF: C32H50O4
  • MW: 498.737
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 597.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 329.3±26.6 °C

beta-D-glucopyranosyl (2alpha,3beta,4beta,19alpha)-2,3,19,23-tetrahydroxyolean-12-en-28-oate

Sericoside is a triterpenoid with anti-inflammatory activity, can be isolated form Terminalia. Sericoside has a strong lipolytic activity. Sericoside can also reduce skin wrinkles and ameliorating skin texture[1][2][3].

  • CAS Number: 55306-04-2
  • MF: C36H58O11
  • MW: 666.839
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 775.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.7±26.4 °C

FOY 251 free base

FOY 251 free base is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].

  • CAS Number: 71079-08-8
  • MF: C16H15N3O4
  • MW: 313.30800
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

columbamine

Columbamine is a quaternary isoquinoline alkaloid isolated from Argemone mexicana.

  • CAS Number: 3621-36-1
  • MF: C20H20NO4
  • MW: 338.377
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lipid M

Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability[1].

  • CAS Number: 2089251-57-8
  • MF: C44H87NO5
  • MW: 710.17
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A