Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

3-Furancarbinol

3-Furanmethanol belongs to the compound class of furan with a wide range of sensory properties. 2-cyanonaphthalenes undergo photocycloaddition reactions with 3-Furanmethanol efficiently and with high degrees of regioselectivity[1][2].

  • CAS Number: 4412-91-3
  • MF: C5H6O2
  • MW: 98.100
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 180.3±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 38.3±0.0 °C

Nagarine

Nagarine, an alkaloid isolated from the roots of Aconitum nagarum Stapf (Ranunculaceae), is used to treat Rheumatic and neuralgic disorders[1].

  • CAS Number: 41849-35-8
  • MF: C34H47NO12
  • MW: 661.73600
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 198-200 °C
  • Flash Point: N/A

Acetylxylan esterases

Acetylxylan esterases (AXEs) belongs to carbohydrate esterase family 4 (CE4). Acetylxylan esterases catalyzes the deacetylation of acetylated carbohydrates[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Yohimban-16-carboxylicacid, 17-hydroxy-, (16a,17a)

Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action, and has the potential for osteoarthritis (OA) research[1][2][3].

  • CAS Number: 522-87-2
  • MF: C20H24N2O3
  • MW: 340.41600
  • Catalog: Cardiovascular Disease
  • Density: 1.39g/cm3
  • Boiling Point: 600ºC at 760mmHg
  • Melting Point: 267-268ºC (dec.)(lit.)
  • Flash Point: 316.6ºC

NCP2 Anchor

NCP2 Anchor can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 52 jumping. It can be used for research of muscular dystrophy[1].

  • CAS Number: 1380600-13-4
  • MF: C38H36N4O8
  • MW: 676.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tert-Butyl (R)-N-benzyl-N-(2-chloropropyl)glycinate

tert-Butyl (R)-N-benzyl-N-(2-chloropropyl)glycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 888494-24-4
  • MF: C16H24ClNO2
  • MW: 297.82
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gadoteridol

Gadoteridol is a gadolinium-based MRI contrast agent, used in the imaging of the central nervous system.

  • CAS Number: 120066-54-8
  • MF: C17H28GdN4O7
  • MW: 557.67700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 668.2ºC at 760 mmHg
  • Melting Point: >225ºC
  • Flash Point: 357.9ºC

MDH1-IN-2

MDH1-IN-2 (Compound 7c) is a potent and selelctive inhibitor of MDH1 with an IC50 of 2.27 μM. MDH1-IN-2 has the potential for the research of cancer diseases[1].

  • CAS Number: 2143463-35-6
  • MF: C25H33NO5
  • MW: 427.53
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Osteoblast-Adhesive Peptide

Osteoblast-Adhesive Peptide is a polypeptide used for chemical modification of biomaterials. Osteoclast Adaptive Peptide increases the adhesion of osteoblasts and has potential applications in dentistry and orthopedics[1][2].

  • CAS Number: 193613-75-1
  • MF: C21H43N11O6
  • MW: 545.64
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diacetoxyscirpenol

Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals[1].

  • CAS Number: 2270-40-8
  • MF: C19H26O7
  • MW: 366.405
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 471.2±45.0 °C at 760 mmHg
  • Melting Point: 162-164℃
  • Flash Point: 162.8±22.2 °C

Petanin

Petanin (chloride) is a p-coumaroyl anthocyanin from the tuber epidermis of colored potato (Solanum tuberosum L. cv JAYOUNG)[1].

  • CAS Number: 69915-09-9
  • MF: C43H49ClO23
  • MW: 969.28800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-D-phe(4-OCH3)-OH

Fmoc-D-Tyr(Me)-OH is a phenylalanine derivative[1].

  • CAS Number: 201335-88-8
  • MF: C25H23NO5
  • MW: 417.454
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 647.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 345.6±31.5 °C

Orbofiban

Orbofiban is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.

  • CAS Number: 163250-90-6
  • MF: C17H23N5O4
  • MW: 361.39600
  • Catalog: Cardiovascular Disease
  • Density: 1.32g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(16R)-Dihydrositsirikine

(16R)-Dihydrositsirikine (19,20-Dihydroisositsirikine) is a natural alkaloid compound[1].

  • CAS Number: 6519-26-2
  • MF: C21H28N2O3
  • MW: 356.46
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 547.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 284.9±28.7 °C

gracillin

Gracillin is a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica with antitumor agent.Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.[1]

  • CAS Number: 19083-00-2
  • MF: C45H72O17
  • MW: 885.043
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 290-293℃ (DEC.)
  • Flash Point: N/A

FMF-06-098-1

FMF-06-098-1 is a highly multitargeted depressant. FMF-06-098-1 can be used to target degradation kinases which degrades AAK1, AΒL2, AURKA, AURKB, BUBIB, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDk6, CDK7, CDK9, CHEK1, CSNKID, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1, and WEE1[1].

  • CAS Number: 2769753-07-1
  • MF: C53H69ClN10O8S2
  • MW: 1073.76
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-acetyl-s-methyl-l-cysteine-d3

N-Acetyl-S-methyl-L-cysteine-d3 is the deuterium labeled C18:1-Ceramide[1].

  • CAS Number: 1279039-06-3
  • MF: C6H8D3NO3S
  • MW: 180.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 85-88°C
  • Flash Point: N/A

VU661

VU661, a phenazine carboxamide, is a modulator of circadian rhythms to produce a period lengthening of the circadian rhythm. VU661 is a redox-active small molecule [1].

  • CAS Number: 37648-76-3
  • MF: C19H13N3O
  • MW: 299.33
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-299375

WAY-299375 is an active molecule for research into amyloid diseases and synucleinopathies.

  • CAS Number: 1005086-69-0
  • MF: C17H16N2
  • MW: 248.322
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 414.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 204.7±28.7 °C

Mal-PEG3-NH2

Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a useful crosslinking reagent with a PEG spacer[1].

  • CAS Number: 2170654-70-1
  • MF: C12H20N2O5
  • MW: 272.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PEN (mouse)

PEN(mouse) (proSAAS(221-242)) is the precursor of a number of peptides that function as neuropeptides[1].

  • CAS Number: 1236955-25-1
  • MF: C102H169N27O34
  • MW: 2317.59
  • Catalog: Neurological Disease
  • Density: 1.47±0.1 g/cm3(Predicted)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

e-Tokoferol

β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol[1].

  • CAS Number: 490-23-3
  • MF: C28H42O2
  • MW: 410.632
  • Catalog: Dipeptidyl Peptidase
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 528.8±49.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 217.0±24.1 °C

3-O-(E)-p-Coumaroylbetulin

3-O-(E)-Coumaroylbetulin (3-(E)-Trans coumaroylbetulin) (compound 6) is a potent antitumor agent[1].

  • CAS Number: 144424-80-6
  • MF: C39H56O4
  • MW: 588.86
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 658.4±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 194.3±18.1 °C

cimilactone A

Cimilactone A is a cycloartane-type triterpene glycoside. Cimilactone A can be isolated from the rhizomes of Cimicifuga foetida[1].

  • CAS Number: 468733-06-4
  • MF: C33H50O9
  • MW: 590.745
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 708.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.4±26.4 °C

erythritol 4-phosphate

D-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate[1].

  • CAS Number: 7183-41-7
  • MF: C4H11O7P
  • MW: 202.10000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Ala-Gln-OH

d-Ala-Gln is adipeptide.

  • CAS Number: 205252-36-4
  • MF: C8H15N3O4
  • MW: 217.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 615.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 326.0±31.5 °C

2-(2-Phenylethyl)chromone

2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis[1].

  • CAS Number: 61828-53-3
  • MF: C17H14O2
  • MW: 250.29200
  • Catalog: Others
  • Density: 1.173g/cm3
  • Boiling Point: 393.1ºC at 760 mmHg
  • Melting Point: 90-91 °C
  • Flash Point: 176.3ºC

PSMA–DA1

PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.

  • CAS Number: 2703051-77-6
  • MF: C50H76IN9O20
  • MW: 1250.09
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

610CP

610CP, a carbopyronine derivative, could be used to label actin filaments. The absorption λmax and fluor λmax values are 609 nM and 634 nM, respectively[1].

  • CAS Number: 1877282-17-1
  • MF: C28H28N2O4
  • MW: 456.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3',4'-O,O-Methylene-(+)-catechin

3',4'-O,O-Methylene-(+)-catechin (compound 10a) is a natural product that can be found in Piptadenia pervillei[1].

  • CAS Number: 89329-14-6
  • MF: C16H14O6
  • MW: 302.279
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 567.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 297.1±30.1 °C