Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

PCTR1 (Protein Conjugates in Tissue Regeneration 1)

PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs)[1].

  • CAS Number: 1810710-59-8
  • MF: C32H47N3O9S
  • MW: 649.8
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-BROMO-BENZENESULFONIC ACID

Piperidine-4-sulfonic acid is a potent GABA agonist with an IC50 of 0.034 μM for the inhibition of the binding of H-GABA[1].

  • CAS Number: 72450-62-5
  • MF: C5H11NO3S
  • MW: 165.21
  • Catalog: GABA Receptor
  • Density: 1.39g/cm3
  • Boiling Point: N/A
  • Melting Point: > 300 °C
  • Flash Point: N/A

L-SERINE BETA-NAPHTHYLAMIDE

L-Serine β-naphthylamide is a serine derivative[1].

  • CAS Number: 888-74-4
  • MF: C13H14N2O2
  • MW: 230.26200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boeravinone A

Boeravinone A is found in Boerhavia diffusa L[1].

  • CAS Number: 114567-33-8
  • MF: C18H14O6
  • MW: 326.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

OAB-14

OAB-14, is a Bexarotene (HY-14171) derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal pathway in APP/PS1 transgenic mice[1][2].

  • CAS Number: 2140911-49-3
  • MF: C32H46N4O2
  • MW: 518.73
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Neotriptonoterpene

Neotriptonoterpene, a compound isolated from T. regelii, shows weak cytotoxic activity against A2780, HepG2 and MCF-7 cells with IC50 values of 65.80, 35.45 and 64.80 µM respectively[1].

  • CAS Number: 117456-86-7
  • MF: C21H30O3
  • MW: 330.461
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 481.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 164.8±22.2 °C

3-Chlorobenzoic acid-d4

3-Chlorobenzoic acid-d4 is the deuterium labeled 3-Chlorobenzoic acid-d4[1].

  • CAS Number: 2098655-72-0
  • MF: C7HD4ClO2
  • MW: 160.59
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

cis-Clopidogrel-MP Derivative

cis-Clopidogrel-MP Derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite[1]. Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor[2].

  • CAS Number: 1122047-98-6
  • MF: C25H26ClNO6S
  • MW: 503.99500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

b,b-Carotene-4,4'-diol Dipalmitate

Lutein dipalmitate (Helenien), a Lutein ester, is a dominant compound in Lutein supplement[1].

  • CAS Number: 547-17-1
  • MF: C72H116O4
  • MW: 1045.69
  • Catalog: Metabolic Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 956.4±65.0 °C at 760 mmHg
  • Melting Point: 82 °C
  • Flash Point: 462.1±32.7 °C

2-Octyl cyanoacrylate

Octan-2-yl 2-cyanoacrylate is a cyanoacrylate compound widely used in industry and medicine as a fast-curing glue or tissue adhesive[1].

  • CAS Number: 133978-15-1
  • MF: C12H19NO2
  • MW: 209.28
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 297.6±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 137.2±9.4 °C

PKH 26

PKH 26 is a lipophilic membrane dye and widely used to determine cell proliferation in heterogeneous cells by flow cytometry. It is a red‐fluorescent dye (Ex/Em=551/567nm)[1][2].

  • CAS Number: 154214-55-8
  • MF: C59H97IN2
  • MW: 961.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Styraxlignolide F

Styraxlignolide F is a natural compoundisolated from Styrax japonica.

  • CAS Number: 823214-06-8
  • MF: C27H34O11
  • MW: 534.552
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 756.4±60.0 °C at 760 mmHg
  • Melting Point: 128-130 °C
  • Flash Point: 250.1±26.4 °C

Xylotetraose

Xylotetraose is a hydrolysis product of Xylan[1]. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose[2]. Xylotetraose can be used for enzyme biochemical analysis[1][3][4].

  • CAS Number: 22416-58-6
  • MF: C20H34O17
  • MW: 546.47400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Complanatin I

Complanatin I is a natural product that can be isolated from Astragalus complanatus[1].

  • CAS Number: 138505-45-0
  • MF: C43H52O20
  • MW: 888.86
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

aglaine c

Aglain C is isolated from A. ponapensis. Aglain C enhances the NF-kB inhibitory activity[1].

  • CAS Number: 177468-85-8
  • MF: C36H42N2O8
  • MW: 630.73
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 839.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 461.8±34.3 °C

ISIS 329993

ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx?has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis

  • CAS Number: 827355-42-0
  • MF:
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NOT Receptor Modulator 1

NOT Receptor Modulator 1 is a nuclear receptor NOT modulator extracted from patent WO 2008034974 A1, Example 39 in table1.

  • CAS Number: 1015231-98-7
  • MF: C22H19ClN2O
  • MW: 362.852
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dihydrobupropion-d9

Dihydrobupropion-d9 is the deuterium labeled Dihydrobupropion[1].

  • CAS Number: 1215071-07-0
  • MF: C13H11ClD9NO
  • MW: 250.81200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-DL-Asp-OH

Glycyl-DL-aspartic acid (Gly-DL-Asp) is an aspartate derivative that can be used for amino acids synthesis[1].

  • CAS Number: 79731-35-4
  • MF: C6H10N2O5
  • MW: 190.15400
  • Catalog: Others
  • Density: 1.499 g/cm3
  • Boiling Point: 468.7ºC at 760 mmHg
  • Melting Point: 199-202℃
  • Flash Point: 237.3ºC

1-Bromo(20,20,20-2H3)icosane

1-Bromoicosane-d3 is the deuterium labeled 1-Bromoicosane[1].

  • CAS Number: 202480-72-6
  • MF: C20H38BrD3
  • MW: 364.462
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 383.2±5.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.4±10.5 °C

thymus peptide C

Thymus peptide C is a hormonal drug, derived from the thymus glands of young calves and acts as a substitute for the physiological functions of the thymus.

  • CAS Number: 316791-23-8
  • MF: CH3
  • MW: 15.03
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Bromo-1,3-difluorobenzene-d3

2-Bromo-1,3-difluorobenzene-d3 is the deuterium labeled 2-Bromo-1,3-difluorobenzene[1].

  • CAS Number: 1219803-73-2
  • MF: C6H3BrF2
  • MW: 192.989
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 149.8±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 53.3±0.0 °C

Dalbergin

Dalbergin is a composition of the extract from the Dalbergia Sissoo Linn. knot wood. Dalbergin demonstrats notable antioxidant ability[1].

  • CAS Number: 482-83-7
  • MF: C16H12O4
  • MW: 268.264
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 489.0±45.0 °C at 760 mmHg
  • Melting Point: 210ºC
  • Flash Point: 187.5±22.2 °C

Ethyl L-threoninate hydrochloride (1:1)

(2S,3R)-Ethyl 2-amino-3-hydroxybutanoate hydrochloride is a threonine derivative[1].

  • CAS Number: 39994-70-2
  • MF: C6H14ClNO3
  • MW: 183.633
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 254ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 107.4ºC

(+)-Norlirioferine

(+)-Norlirioferine is an alkaloid compound. (+)-Norlirioferine inhibits the cell growth of macrophages and VERO cells[1].

  • CAS Number: 86941-27-7
  • MF: C19H21NO4
  • MW: 327.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-D-Lys(Boc)-OH

N3-D-Lys(Boc)-OH is a click chemistry reagent containing an Azide[1].

  • CAS Number: 1178899-92-7
  • MF: C11H20N4O4
  • MW: 272.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-β-Peltatin-5-O-beta-D-glucopyranoside

(-)-β-Peltatin-5-O-beta-D-glucopyranoside is an active compound. (-)-β-Peltatin-5-O-beta-D-glucopyranoside can be isolated from P. peltatum L[1].

  • CAS Number: 11024-59-2
  • MF: C28H32O13
  • MW: 576.54600
  • Catalog: Others
  • Density: 1.468g/cm3
  • Boiling Point: 798ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.2ºC

Guaiol

Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities[1][2][3].

  • CAS Number: 489-86-1
  • MF: C15H26O
  • MW: 222.37
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 288.0±0.0 °C at 760 mmHg
  • Melting Point: 91-93ºC(lit.)
  • Flash Point: 113.6±15.6 °C

9,10-dihydroxystearic acid

9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice[1].

  • CAS Number: 120-87-6
  • MF: C18H36O4
  • MW: 316.476
  • Catalog: PROTAC Linker
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 481.6±25.0 °C at 760 mmHg
  • Melting Point: 92-94ºC
  • Flash Point: 259.2±19.7 °C

Guanosine 5'-triphosphate(GTP)-d4 ammonium salt

Guanosine 5'-triphosphate(GTP)-d4 (ammonium salt) is the deuterium labeled Guanosine 5'-triphosphate(GTP) ammonium salt[1].

  • CAS Number: 2483831-83-8
  • MF: C10H24D4N9O14P3
  • MW: 595.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A