Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Ethanethioamide,S-oxide (9CI)

Thioacetamide-S-oxide, a Thiocetamide metabolite, is a δ-aminolevulinic acid (ALA) synthetase inhibitor[1].

  • CAS Number: 2669-09-2
  • MF: C2H5NOS
  • MW: 91.13
  • Catalog: Metabolic Disease
  • Density: 1.27g/cm3
  • Boiling Point: 146.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 42.3ºC

10-Hydroxy-2,6,10-trimethyl-2,6,11-dodeca-4-one

Hydroxy-2,6,10-trimethyl-2,6,11-dodeca-4-one is a natural product that can be found in Solanaceae[1].

  • CAS Number: 54877-97-3
  • MF: C15H24O2
  • MW: 236.35000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PI5P4Ks-IN-1

PI5P4Ks-IN-1 (compound 7) is an active compound with no detectable inhibition of the PI5P4K α or β isoforms[1].

  • CAS Number: 959560-36-2
  • MF: C20H17N3S
  • MW: 331.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Oxo Prasugrel-d4 hydrochloride

2-Oxo Prasugrel-d4 (hydrochloride) is the deuterium labeled 2-Oxo Prasugrel hydrochloride[1].

  • CAS Number: 2012598-55-7
  • MF: C18H15D4ClFNO2S
  • MW: 371.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Adipokinetic Hormone G (Gryllus bimaculatus)

Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans[1][2][3].

  • CAS Number: 113800-65-0
  • MF: C43H57N11O12
  • MW: 919.979
  • Catalog: Metabolic Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1183.0±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 669.2±37.1 °C

[Tyr11]-Somatostatin

[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1].

  • CAS Number: 59481-27-5
  • MF: C76H104N18O20S2
  • MW: 1653.878
  • Catalog: Neurological Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 2000.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1163.7±34.3 °C

TAM558 intermediate-2

TAM558 intermediate-24 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity[1].

  • CAS Number: 2135877-76-6
  • MF: C29H50N4O5S
  • MW: 566.80
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ogerin

Ogerin is a selective GPR68 positive allosteric modulator, with a pEC50 of 6.83. Ogerin shows inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptoor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor. Ogerin blocks recall in fear conditioning in mice[1].

  • CAS Number: 1309198-71-7
  • MF: C17H17N5O
  • MW: 307.35
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,8-Di-O-methylellagic acid

3,3'-Di-O-methylellagic acid obtained from Euphorbia adenochlora selectively inhibits the formation of acid-fastness in mycobacteria without retardation of their growth. 3,3'-di-O-methylellagic acid as a hepatoprotective compound is apparently due to its antioxidative effect[1][2].

  • CAS Number: 2239-88-5
  • MF: C16H10O8
  • MW: 330.246
  • Catalog: Infection
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 675.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.3±25.0 °C

(2H12)Coronene

Coronene-d12 is the deuterium labeled Coronene[1].

  • CAS Number: 16083-32-2
  • MF: C24D12
  • MW: 312.426
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 525.6±17.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 265.2±15.1 °C

NSP-SA-NHS

NSP-SA-NHS is a chemiluminescent acridinium ester.

  • CAS Number: 199293-83-9
  • MF: C32H31N3O10S2
  • MW: 681.73
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].

  • CAS Number: 2414393-48-7
  • MF: C12H14O3
  • MW: 206.24
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Actinoquinol

Actinoquinol is a UVB absorber that can be helpful for the human eye in the defence against photooxidative and other oxidative processes[1].

  • CAS Number: 15301-40-3
  • MF: C11H11NO4S
  • MW: 253.274
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: >300°C
  • Flash Point: N/A

Cetrimonium bromide-d42

Cetrimonium (bromide)-d42 is the deuterium labeled Cetrimonium bromide[1].

  • CAS Number: 907216-28-8
  • MF: C19H42BrN
  • MW: 364.44700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

phenolphthalein glucuronic acid sodium salt

Phenolphthalein glucuronide sodium is a substrate to determine the β –glucuronidase[1].

  • CAS Number: 6820-54-8
  • MF: C26H21NaO10
  • MW: 516.42900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Asp-OMe

H-Asp-OMe is an aspartic acid derivative[1].

  • CAS Number: 17812-32-7
  • MF: C5H9NO4
  • MW: 147.129
  • Catalog: Others
  • Density: 1.299 g/cm3
  • Boiling Point: 272.7±30.0 °C at 760 mmHg
  • Melting Point: 186ºC
  • Flash Point: 118.7±24.6 °C

Boc-D-Tyr(Me)-OH

Boc-D-Tyr(Me)-OH is a phenylalanine derivative[1].

  • CAS Number: 68856-96-2
  • MF: C15H21NO5
  • MW: 295.331
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 462.0±40.0 °C at 760 mmHg
  • Melting Point: 93.0 to 97.0 °C
  • Flash Point: 233.2±27.3 °C

2-Amino-6-methylheptane hydrochloride

2-Amino-6-methylheptane hydrochloride is a local anesthetic and vasoconstrictor, but mainly as a pharmaceutical intermediate of octamylamine.

  • CAS Number: 5984-59-8
  • MF: C8H20ClN
  • MW: 165.70400
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 155ºC at 760 mmHg
  • Melting Point: 139-140 ºC
  • Flash Point: 48.9ºC

Fmoc-3-(1-Naphthyl)-L-alanine

Fmoc-1-Nal-OH is an alanine derivative[1].

  • CAS Number: 96402-49-2
  • MF: C28H23NO4
  • MW: 437.487
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 690.7±50.0 °C at 760 mmHg
  • Melting Point: 182 °C
  • Flash Point: 371.6±30.1 °C

ularitide

Ularitide (Urodilatin), natriuretic peptide, is a vasodilator. Ularitide binds to and activates renal receptors. Ularitide also regulates renal dopamine metabolism Ularitide can be used in the research of heart failure[1][2][4][5].

  • CAS Number: 118812-69-4
  • MF: C145H234N52O44S3
  • MW: 3505.927
  • Catalog: Cardiovascular Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TA-1801

TA-1801 is a hypolipidemic agent.

  • CAS Number: 88352-44-7
  • MF: C17H14ClNO4
  • MW: 331.75000
  • Catalog: Metabolic Disease
  • Density: 1.275g/cm3
  • Boiling Point: 471ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.6ºC

7-Amino-4-methylcoumarin

7-amino-4-methylcoumarin has been used as a fluorogenic probe for many serine proteases.

  • CAS Number: 26093-31-2
  • MF: C10H9NO2
  • MW: 175.184
  • Catalog: Dye Reagents
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 378.3±37.0 °C at 760 mmHg
  • Melting Point: 223-226 °C(lit.)
  • Flash Point: 216.9±24.0 °C

Triethanolamine

Triethanolamine is a viscous organic compound that is both a tertiary amine and a triol. Triethanolamine (TEOA) can be used for chromatographic modification reagent that possesses some chemical properties. [1]Triethanolamine (TEA) is applied as a stabilizer and pH adjusting chemical for the aminolysis of polyester surface and enhancing the surface reactivity along with synthesis and deposition of ZnO nanoparticles on the fabric. [2]

  • CAS Number: 102-71-6
  • MF: C6H15NO3
  • MW: 149.188
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 335.4±0.0 °C at 760 mmHg
  • Melting Point: 21 °C
  • Flash Point: 185.0±0.0 °C

GPR52 receptor modulator 1

GPR52 receptor modulator 1 (Procedure 1) is a GPR52 receptor modulator with the potential to study neuropsychiatric diseases[1].

  • CAS Number: 2642079-89-6
  • MF: C19H14F4N4O
  • MW: 390.33
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diphenyl Ether-d10

Diphenyl Ether-d10 is the deuterium labeled Diphenyl Ether[1].

  • CAS Number: 93952-05-7
  • MF: C12D10O
  • MW: 180.26900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gamma-Tocotrienol

γ-Tocotrienol is an active form of vitamin E[1].

  • CAS Number: 14101-61-2
  • MF: C28H42O2
  • MW: 410.632
  • Catalog: Inflammation/Immunology
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 530.8±49.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.4±24.1 °C

(Asp28)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt

(Asp28)-Glucagon (1-29) (human, rat, porcine) is an optimized structure of glucagon, the 28th position is replaced by aspartic acid (Asp) which significantly increases the aqueous solubility of glucagon in a physiological pH buffer, has the same activity as glucagon[1].

  • CAS Number: 1037751-81-7
  • MF: C153H224N42O50S
  • MW: 3483.73
  • Catalog: Metabolic Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clothixamide

Clothixamide is a thiazide derivative. It is used to treat psychiatric disorders.

  • CAS Number: 4177-58-6
  • MF: C24H28ClN3OS
  • MW: 442.01700
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

n-methyl-l-phenylalanine hydrochloride

N-Methyl-L-phenylalanine hydrochloride is a phenylalanine derivative[1].

  • CAS Number: 66866-67-9
  • MF: C10H14ClNO2
  • MW: 215.67700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3-Dihydroxypropyl ((R)-2-(oleoyloxy)-3-(pentadecanoyloxy)propyl) phosphate-d7 sodium

2,3-Dihydroxypropyl ((R)-2-(oleoyloxy)-3-(pentadecanoyloxy)propyl) phosphate-d7 (sodium) is deuterium labeled 2,3-Dihydroxypropyl ((R)-2-(oleoyloxy)-3-(pentadecanoyloxy)propyl) phosphate (sodium).

  • CAS Number: 2260669-42-7
  • MF: C39H68D7NaO10P
  • MW: 765.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A