Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Ile-OAll.TosOH

H-Ile-OAll.TosOH is an isoleucine derivative[1].

  • CAS Number: 88224-05-9
  • MF: C16H25NO5S
  • MW: 343.43800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 487.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 248.5ºC

Spermine NONOate

Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing[1].

  • CAS Number: 136587-13-8
  • MF: C10H26N6O2
  • MW: 262.352
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 425.4±55.0 °C at 760 mmHg
  • Melting Point: 105-107ºC
  • Flash Point: 211.1±31.5 °C

3-Epi-25-Hydroxyvitamin D3-d3

3-Epi-25-Hydroxyvitamin D3-d3 is the deuterium labeled 3-Epi-25-Hydroxyvitamin D3[1].

  • CAS Number: 2206653-61-2
  • MF: C27H41D3O2
  • MW: 403.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,7-dichloro-2-(4,7-dichloro-3-oxobenzo[b]thien-2(3H)-ylidene)benzo[b]thiophene-3(2H)-one

C.I.Pigment red 88 is a red pigment that can be used in plasticised Poly(viny1 chloride) (PVC)[1].

  • CAS Number: 14295-43-3
  • MF: C16H4Cl4O2S2
  • MW: 434.14400
  • Catalog: Others
  • Density: 1.81g/cm3
  • Boiling Point: 526.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 272.2ºC

Solvent Green 7

Pyranine as a new class of fluorescent chemosensor for the Cu+ ion is reported.

  • CAS Number: 6358-69-6
  • MF: C16H7Na3O10S3
  • MW: 524.385
  • Catalog: Dye Reagents
  • Density: 2.15
  • Boiling Point: 171-178 °C10 mm Hg(lit.)
  • Melting Point: 62-63.5 °C(lit.)
  • Flash Point: 250 °C

Topsalysin

Topsalysin (PRX-302; PRX302; PSA-PAH1) is a PSA-activated protoxin, a pore-forming protein (synthetic proaerolysin) fusion protein with human prostate-specific antigen. Topsalysin has tumor suppression effect in mice modle[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone

3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone displays cytotoxicity of 1.32, 3.92 and 5.22 μm against the human cervical carcinoma HeLa, human breast carcinoma MCF-7, and human hepatocarcinoma Hep3B cells[1].

  • CAS Number: 1334309-44-2
  • MF: C30H34O6
  • MW: 490.59
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 708.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 231.2±26.4 °C

TREMULACIN

Tremulacin is an important glucoside component of several Populus species barks and leaves[1].

  • CAS Number: 29836-40-6
  • MF: C27H28O11
  • MW: 528.50500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3',6'-bis(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)-spiro[isobenzofuran-1(3h),9'-[9h]xanthen]-3-one

Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe[1].

  • CAS Number: 817170-66-4
  • MF: C32H34B2O7
  • MW: 552.23000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zolbetuximab

Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kuwanon E

Kuwanon E is a flavonoid isolated from Morus alba, cytotoxic to human monocytic leukemic cell lines, and reduces the level of IL-1β[1].

  • CAS Number: 68401-05-8
  • MF: C25H28O6
  • MW: 424.486
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 678.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232.0±25.0 °C

2'-Deoxyadenosine monohydrate

2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.

  • CAS Number: 16373-93-6
  • MF: C10H15N5O4
  • MW: 269.26
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 627.2±65.0 °C at 760 mmHg
  • Melting Point: 185-187ºC
  • Flash Point: 333.1±34.3 °C

Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide[1].

  • CAS Number: 1266350-99-5
  • MF: C29H36N2O7
  • MW: 524.605
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 717.1±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 387.5±32.9 °C

N-Oxalylglycine

N-Oxalylglycine (N-Oxaloglycine) is a broad-spectrum 2-oxoglutarate oxygenase inhibitor. N-Oxalylglycine can be used in studies on the hypoxic response and chromatin modifications in animals[1][1].

  • CAS Number: 5262-39-5
  • MF: C4H5NO5
  • MW: 147.09
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,5,6-Trichloroguaiacol

4,5,6-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills[1].

  • CAS Number: 2668-24-8
  • MF: C7H5Cl3O2
  • MW: 227.472
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 291.1±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 129.9±25.9 °C

4-di-2-asp

4-Di-2-ASP, a styryl pyridinium fluorescent dye, is a vital mitochondrial marker. 4-Di-2-ASP shows reliable and specific labelling of pulmonary NEBs (neuroepithelial bodies)[1].

  • CAS Number: 105802-46-8
  • MF: C18H23IN2
  • MW: 394.29300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 214-216ºC(lit.)
  • Flash Point: N/A

H-His-Trp-OH

H-His-Trp-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 23403-90-9
  • MF: C17H19N5O3
  • MW: 341.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Toddanol

(-)-Toddanol, a coumarin, can be isolated from the root of Toddalia asiatica[1].

  • CAS Number: 77715-99-2
  • MF: C16H18O5
  • MW: 290.311
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 480.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.4±22.2 °C

H-Glu-Glu-Leu-OH

Glu-Glu-Leu is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 189080-99-7
  • MF: C16H27N3O8
  • MW: 389.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-(+)-Talose-13C,d1

D-(+)-Talose-13C,d1 is the deuterium and 13C labeled D-(+)-Talose[1].

  • CAS Number: 370565-97-2
  • MF: C513CH11DO6
  • MW: 182.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phillygenin

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.In vivo: The reference for rat is 5.6 mg/m l ( i.v).

  • CAS Number: 487-39-8
  • MF: C21H24O6
  • MW: 372.412
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 534.9±50.0 °C at 760 mmHg
  • Melting Point: 133ºC
  • Flash Point: 277.3±30.1 °C

Tupichinol C

Tupichinol C is a flavonoid, isolated from Tupistra chinensis[1].

  • CAS Number: 118204-66-3
  • MF: C15H14O3
  • MW: 242.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ficusonolide

Ficusonolide has significant antidiabetic activity with a possible mechanism of interaction with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.

  • CAS Number: 1800503-81-4
  • MF: C30H46O3
  • MW: 454.68
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-P7C3-OMe

(S)-P7C3-OMe, P7C3-A20 hydroxylated analog, is the (S)-enantiomer of P7C3-OMe. P7C3-OMe is a pro-neurogenic compound, can be used for the research of neuropsychiatric and/or neurodegenerative disease[1].

  • CAS Number: 1235481-43-2
  • MF: C22H20Br2N2O2
  • MW: 504.21
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 680.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 365.3±31.5 °C

MetAP2-IN-1

MetAP2-IN-1 is a MetAP2 inhibitor. MetAP2-IN-1 can be used for research in conditions mediated by angiogenesis[1].

  • CAS Number: 5301-98-4
  • MF: C8H6BrN3
  • MW: 224.06
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Bromo-6-nitrophenol

2-Bromo-6-nitrophenol is converted via 2-bromo-6-aminophenol to N-acetyl-2-bromo-6-aminophenol[1].

  • CAS Number: 13073-25-1
  • MF: C6H4BrNO3
  • MW: 218.005
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 227.2±20.0 °C at 760 mmHg
  • Melting Point: 66-70 °C(lit.)
  • Flash Point: 91.2±21.8 °C

Vincaleukoblastine, 3',4'-didehydro-4'-deoxy

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves[1].

  • CAS Number: 38390-45-3
  • MF: C46H56N4O8
  • MW: 792.959
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 205-207ºC
  • Flash Point: N/A

Rhaponticin 6''-O-gallate

Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages[1].

  • CAS Number: 94356-23-7
  • MF: C28H28O13
  • MW: 572.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-Lyoniresinol

(-)-Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. (-)-Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM[1].

  • CAS Number: 31768-94-2
  • MF: C22H28O8
  • MW: 420.453
  • Catalog: Others
  • Density: 1.272±0.06 g/cm3
  • Boiling Point: 617.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.3±31.5 °C

Anticancer agent 168

Anticancer agent 168 (compound d16) is a inhibitor of DNA2. Anticancer agent 168 induces apoptosis and cell-cycle arrest mainly at S-phase, and exhibits anticancer activities and overcomes chemotherapy resistance in mutp53-bearing cancers[1].

  • CAS Number: 207399-56-2
  • MF: C16H11ClN2O6
  • MW: 362.72
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A