H-Phe-OMe.hydrochloride is a phenylalanine derivative[1].
H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound[1].
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) were activated using SPDP .
N-Acetyllactosamine (LacNAc), a nitrogen-containing disaccharide, is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects[1][2].
D-Galactose-13C-1 is the 13C labeled D-galactopyranose[1].
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-phenylalanine is a phenylalanine derivative[1].
Calpain-1 (pig) (μ-Calpain) is an intracellular Ca2+-regulated cysteine protease. Calpain-1 (pig) exhibits neuroprotective effect[1][2].
Fura-2 AM is a ratiometric fluorescent Ca2+ indicator.
GalNAcβ(1-4)GlcNAc-β-pNP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
1,1,1,3,10,11-Hexachloroundecane is a kind of polychlorinated alkane (PCA) that has a long carbon chain length[1].
N-[4-(2-Chlorophenoxy)phenylsulfonyl]-DL-alanine is an alanine derivative[1].
5-Bromopentanoic-3,3,4,4 Acid-d4 is the deuterium labeled 5-Bromopentanoic acid[1].
Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].
1,8-Dichloroanthraquinone, an anthraquinone, is an inhibitor of sulfide production by sulfate-reducing bacteria[1].
Isovalerylcarnitine is a product of the catabolism of L-leucine. It increases calpain activity.
(S)-2-((tert-Butoxycarbonyl)amino)-2-cyclopentylacetic acid is a Glycine (HY-Y0966) derivative[1].
Methyl p-hydroxyphenyllactate (MeHPLA) is an important cell growth-regulating agent which binds to nuclear type II binding sites in normal and malignant cells[1].
C15 Ceramide-1-phosphate-d7 is deuterium labeled C15 Ceramide-1-phosphate.
Lithium 3,5-diiodosalicylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P.
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent[1].
Tributyl citrate is a citric acid ester. Tributyl citrate can be used as an excipient, such as plasticizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Nitazoxanide D4 is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.
3,3',4,4'-Tetrachloro-1,1'-biphenyl-d6 is the deuterium labeled 3,3',4,4'-Tetrachloro-1,1'-biphenyl[1].
(R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor, with good pharmacokinetic properties. (R)-IDO/TDO-IN-1 exhibits anti-tumor activity in MC38 xenograft model. (R)-IDO/TDO-IN-1 shows synergistic effect with anti-PD-1 monoclonal antibody (SHR-1210)[1].
RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].
(BHQ-3)-OSu hexafluorophosphate is used for fluorescent labeling of protease substrates[1].
GW806742X is a Mixed Lineage Kinase Domain-Like (MLKL) inhibitor which binds the MLKL pseudokinase domain with a Kd value of 9.3 μM and anti-necroptosis activity. GW806742X has activity against VEGFR2[1][2].
8-Hydroxyquinoline is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.