Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Lys-Phe-Glu-Arg-Gln

Lys-Phe-Glu-Arg-Gln can enhance the degradation of cytosolic proteins in human diploid fibroblasts deprived of serum[1].

  • CAS Number: 115084-19-0
  • MF: C31H50N10O9
  • MW: 706.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganoderic acid G

Ganoderic acid G is a triterpene isolated from the surface part of gills of Ganoderma lucidum[1].

  • CAS Number: 98665-22-6
  • MF: C30H44O8
  • MW: 532.66600
  • Catalog: Others
  • Density: 1.27g/cm3
  • Boiling Point: 722.7ºC at 760 mmHg
  • Melting Point: 224-226 °C
  • Flash Point: 404.8ºC

NE 10790

NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent.

  • CAS Number: 152831-36-2
  • MF: C8H10NO6P
  • MW: 247.14200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kadsurin A analogue-1

Kadsurin A analogue-1 (Compound 8) is a lignan can be extracted from Piper argyrophylum[1].

  • CAS Number: 155551-59-0
  • MF: C20H20O5
  • MW: 340.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

((2,5-Dimethylphenyl)sulfonyl)-L-alanine

((2,5-Dimethylphenyl)sulfonyl)-L-alanine is an alanine derivative[1].

  • CAS Number: 1103980-04-6
  • MF: C11H15NO4S
  • MW: 257.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DiSBAC10

DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

  • CAS Number: 169211-45-4
  • MF: C51H88N4O4S2
  • MW: 885.40
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 844.6±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 464.6±37.1 °C

Benzo[d]thiazol-2-amine

Benzo[d]thiazol-2-amine is a favorable ligand to synthesize dinuclear complexes which contain nitrogen heterocycle[1].

  • CAS Number: 136-95-8
  • MF: C7H6N2S
  • MW: 150.201
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 307.5±25.0 °C at 760 mmHg
  • Melting Point: 126-129 °C(lit.)
  • Flash Point: 139.8±23.2 °C

D-Fructose-d4

D-Fructose-d4 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].

  • CAS Number: 478518-49-9
  • MF: C6H8D4O6
  • MW: 184.18100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Monarsen

Monarsen (EN101) is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,5-Difluorobenzoic acid-d3

3,5-Difluorobenzoic acid-d3 is the deuterium labeled 3,5-Difluorobenzoic acid[1].

  • CAS Number: 934397-71-4
  • MF: C7H4F2O2
  • MW: 158.10200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 41335-62-0
  • MF: C15H10ClNO4S
  • MW: 335.762
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 564.7±56.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.3±31.8 °C

Desmethoxyyangonin

Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.

  • CAS Number: 15345-89-8
  • MF: C14H12O3
  • MW: 228.243
  • Catalog: Monoamine Oxidase
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 440.0±45.0 °C at 760 mmHg
  • Melting Point: 138-140ºC
  • Flash Point: 188.0±23.3 °C

H-Met-Met-OH

H-Met-Met-OH (L-Methionyl-L-methionine) is a dipeptide composed of two methionine residues[1].

  • CAS Number: 7349-78-2
  • MF: C10H20N2O3S2
  • MW: 280.40700
  • Catalog: Others
  • Density: 1.237g/cm3
  • Boiling Point: 555.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 289.5ºC

Tridodecyl methyl ammonium chloride

Tridodecyl methyl ammonium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 7173-54-8
  • MF: C37H78ClN
  • MW: 572.47500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 110-112 °C(lit.)
  • Flash Point: N/A

1-(Furan-2-yl)ethanone

2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime[1][2].

  • CAS Number: 1192-62-7
  • MF: C6H6O2
  • MW: 110.111
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 183.4±0.0 °C at 760 mmHg
  • Melting Point: 26-28 °C(lit.)
  • Flash Point: 71.1±0.0 °C

3,5-Diiodo-L-tyrosine dihydrate

3,5-Diiodo-L-tyrosine is a tyrosine derivative[1].

  • CAS Number: 300-39-0
  • MF: C9H13I2NO5
  • MW: 469.012
  • Catalog: Others
  • Density: 2.405g/cm3
  • Boiling Point: 410.5ºC at 760 mmHg
  • Melting Point: 200 °C (dec.)(lit.)
  • Flash Point: 202.1ºC

N-Methyl(2H3)acetamide

N-Methylacetamide-d3-1 is the deuterium labeled N-Methylacetamide[1].

  • CAS Number: 3669-69-0
  • MF: C3H4D3NO
  • MW: 76.112
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 206.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 108.3±0.0 °C

Azelaic acid

Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.

  • CAS Number: 123-99-9
  • MF: C9H16O4
  • MW: 188.221
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 286 ºC (100 mmHg)
  • Melting Point: 98-103 ºC
  • Flash Point: 215 ºC

Methyl 2,6-dihydroxybenzoate

Methyl 2,6-dihydroxybenzoate is a volatile, that can be isolated from whole flowers and corolla of Primula spectabilis[1].

  • CAS Number: 2150-45-0
  • MF: C8H8O4
  • MW: 168.147
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 253.6±20.0 °C at 760 mmHg
  • Melting Point: 67-70 °C(lit.)
  • Flash Point: 101.1±15.3 °C

LX7101

LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively; also inhibits PKA with an IC50 less than 1 nM.

  • CAS Number: 1192189-69-7
  • MF: C23H29N7O3
  • MW: 451.52100
  • Catalog: ROCK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ASGPR modulator-1

ASGPR modulator-1 (Compound 5TJX) is a macrocycle compound that can be uesd for protein-protein interaction study[1].

  • CAS Number: 2052968-88-2
  • MF: C29H33N7O3
  • MW: 527.62
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Decuroside V

Decuroside V is a coumarin-glycoside found in a Chinese Drug “Qian-Hu”[1].

  • CAS Number: 96648-59-8
  • MF: C20H24O10
  • MW: 424.40
  • Catalog: Others
  • Density: 1.58±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt

8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe[1].

  • CAS Number: 82962-86-5
  • MF: C17H9Na3O10S3
  • MW: 538.41200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 253-260ºC (dec.)(lit.)
  • Flash Point: N/A

Anivamersen sodium

Anivamersen sodium is an RNA aptamer to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. REG1 is a novel anticoagulation system consisting of pegnivacogin, an RNA aptamer inhibitor of coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide.

  • CAS Number: 959716-31-5
  • MF: C157H194N56Na14O103P14
  • MW: 5269.10
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Scholaricine

Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].

  • CAS Number: 99694-90-3
  • MF: C20H24N2O4
  • MW: 356.42
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 519.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 268.0±30.1 °C

PHI-27 (porcine)

PHI-27 (porcine) is a 27 amino acid peptide.PHI-27 (porcine) is used to find peptide hormones and other active peptides[1].

  • CAS Number: 80458-29-3
  • MF: C136H216N36O40
  • MW: 2995.39000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methylanisole-13C

4-Methylanisole-13C is the 13C-labeled 4-Methylanisole. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[1].

  • CAS Number: 117923-70-3
  • MF: C713CH10O
  • MW: 123.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2'-Amino-2'-deoxycytidine

2′-Amino-2′-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 26889-42-9
  • MF: C9H14N4O4
  • MW: 242.23
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

h-3,5-dibromo-d-tyr-oh

3,5-Dibromo-D-tyrosine is a tyrosine derivative[1].

  • CAS Number: 50299-42-8
  • MF: C9H9Br2NO3
  • MW: 338.981
  • Catalog: Others
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 416.6±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.7±28.7 °C

Mergetpa

Mergetpa is a carboxypeptidase inhibitor used to block the conversion of kinins and B2 receptor antagonists to metabolites lacking the C-terminal arginine[1].

  • CAS Number: 77102-28-4
  • MF: C7H15N3O2S2
  • MW: 237.34
  • Catalog: Carboxypeptidase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A