PI3K-IN-37 (Example 84.1) is a PI3K α/β/δ inhibitor with IC50s of 6, 8, 4 nM, respectively. PI3K-IN-37 can also inhibit mTOR (IC50=4 nM)[1].
((2,6-Dichlorophenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].
Glu-Ser is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
Z-D-Lys-OH is a lysine derivative[1].
N-Benzyl-N,N-diethylethanaminium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Mangostanol ((+)-Mangostanol)) is a natural polyoxygenated xanthone mangostanol isolated from the shell of Garcinia mangostana which has inhibitory effect on cAMP phosphodiesterase (PDE)[1].
2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide is a lignan with a γ-butenolide structure and 10-epi-olguine. 2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide is isolated from the aerial parts of the medicinal plant Hyptis capitata[1].
Saikosaponin F is a component found in Bupleurum (B.) falcatum L[1].
MeOSuc-Ala-Phe-Lys-AMC TFA is a peptide substrate of plasmin[1].
DPhPC is a phospholipid used to synthesize bilayer vesicles. DPhPC bilayers do not permit ions to leak in the absence of a pore/ion channel, which can be used for studies on channel proteins[1][2].
Xylenol Orange (tetrasodium), metal indicator, AR is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
8-Chloro-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
1-Bromononane-d19 is the deuterium labeled 1-Bromononane[1].
Boc-Nle-OH.DCHA is a leucine derivative[1].
Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088). Isoxepac is a nonsteroidal anti-inflammatory agent[1].
(4Z)-Lachnophyllum lactone is a enyne derivative. (4Z)-Lachnophyllum lactone shows growth inhibitory activity against Lemna paucicostata (IC50=104 μM), which is a problematic and invasive weed[1].
4-Nitrophenyl β-D-fuco-pyran-oside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.
H-Cys(Bzl)-OH is a cysteine derivative[1].
Benzoylcholine Iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
2'-Deoxycytidine-d2 monohydrate is the deuterium labeled 2'-Deoxycytidine[1].
C24-Ceramide is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide induces time-dependent changes in membrane properties. C24-Ceramide induces membrane reorganization[1][2].
Fmoc-N-Me-Asp(OtBu)-OH is an aspartic acid derivative[1].
Glutamate dehydrogenase NAD(P) (GLDH) can be found in hepatocytes, renal tissue, brain, muscle, and intestinal cells. Glutamate dehydrogenase NAD(P) is often used in biochemical studies. Glutamate dehydrogenase is a mitochondrial enzyme, it catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG) as part of the urea cycle[1].
Cy5-PEG3-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].
Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions[1].
Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity[1].
H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay[1].
1-Methoxymethyl-β-carboline is a natural product isolated from the root of Eurycoma longifolia[1].