Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4-(2H4)Pyridinecarboxylic acid

Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid[1]. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C[2].

  • CAS Number: 53907-55-4
  • MF: C6HD4NO2
  • MW: 127.134
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 396.0±15.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.3±20.4 °C

Photobiotin acetate salt

Photobiotin acetate salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 96087-38-6
  • MF: C25H39N9O6S
  • MW: 593.69900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+/-)-4-Hydroxy Mephenytoin-d3

4-Hydroxymephenytoin D3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate[1][2].

  • CAS Number: 1173022-56-4
  • MF: C12H11D3N2O3
  • MW: 237.270
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

9-Hydroxyeriobofuran

9-Hydroxyeriobofuran is a natural product that can be found in Pyracantha koidzumii. 9-Hydroxyeriobofuran inhibits HEMn cell growth[1].

  • CAS Number: 167278-41-3
  • MF: C14H12O5
  • MW: 260.242
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 355.1±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 168.6±26.5 °C

2,8-Dimethyladenosine

2,8-Dimethyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 63954-66-5
  • MF: C12H17N5O4
  • MW: 295.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quinoxaline,2,3-di-2-furanyl

2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM)[1].

  • CAS Number: 57490-73-0
  • MF: C16H10N2O2
  • MW: 262.26
  • Catalog: Others
  • Density: 1.272g/cm3
  • Boiling Point: 360.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 117.2ºC

Thifensulfuron-methyl

Thifensulfuron-methyl is a sulfonylurea herbicide and mainly used for control of broadleaved weeds in wheat, corn, and soybean fields[1].

  • CAS Number: 79277-27-3
  • MF: C12H13N5O6S2
  • MW: 387.39200
  • Catalog: Others
  • Density: 1.56 g/cm3
  • Boiling Point: N/A
  • Melting Point: 176°C
  • Flash Point: N/A

2’-O-Methyl-5-methyl-4-thiouridine

2’-O-Methyl-5-methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 2095417-26-6
  • MF: C11H16N2O5S
  • MW: 288.32
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

β-Amyloid 35-42

β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.

  • CAS Number: 183292-41-3
  • MF: C33H60N8O9S
  • MW: 744.94
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DL-Glutamic acid

DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

  • CAS Number: 617-65-2
  • MF: C5H9NO4
  • MW: 147.129
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 333.8±32.0 °C at 760 mmHg
  • Melting Point: 194ºC
  • Flash Point: 155.7±25.1 °C

N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide

N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide (Calcium ionophore II) is a lipophilic ionophore that can be used in preparing calcium ion-selective electrode[1].

  • CAS Number: 74267-27-9
  • MF: C28H48N2O3
  • MW: 460.69
  • Catalog: Others
  • Density: 1.07g/cm3
  • Boiling Point: 613.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 325ºC

KT182

KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1].

  • CAS Number: 1402612-62-7
  • MF: C27H26N4O2
  • MW: 438.52
  • Catalog: MAGL
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sculponeatin O

Sculponeatin O is a ent-kaurane diterpene derivative compound isolated from the plant Isodon sculponeata[1].

  • CAS Number: 1169806-00-1
  • MF: C28H40O4
  • MW: 440.615
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 559.6±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 179.8±18.1 °C

1,2-Dihexanoyl-sn-glycero-3-PC

1,2-dihexanoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 34506-67-7
  • MF: C20H40NO8P
  • MW: 453.50700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(1β,3β)-Spirosta-5,25(27)-dien-1,3-diol

Neoruscogenin, a member of the steroidal sapogenin family, is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1)[1].

  • CAS Number: 17676-33-4
  • MF: C27H40O4
  • MW: 428.604
  • Catalog: ROR
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 566.6±50.0 °C at 760 mmHg
  • Melting Point: 196-198℃
  • Flash Point: 296.4±30.1 °C

Fmoc-His(1-Me)-OH

Fmoc-1-methyl-L-histidine is a Fmoc protected amino acid and can be used as an intermediate for peptide synthesis[1].

  • CAS Number: 202920-22-7
  • MF: C22H21N3O4
  • MW: 391.42000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone

(2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research[1][2].

  • CAS Number: 204935-85-3
  • MF: C21H22O6
  • MW: 370.396
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 631.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 224.9±25.0 °C

2-Undecanol

2-Undecanol (Undecan-2-ol) is a male specific volatile identified from the sap beetle Lobiopa insularis. 2-undecanol is a flower emitted volatile, used by various species of Hymenoptera as a pheromone component[1].

  • CAS Number: 1653-30-1
  • MF: C11H24O
  • MW: 172.30800
  • Catalog: Others
  • Density: 0.828 g/mL at 25 °C(lit.)
  • Boiling Point: 130-131 °C28 mm Hg(lit.)
  • Melting Point: 2-3 °C
  • Flash Point: 226 °F

Osivelotor

Osivelotor is an allosteric modulator of haemoglobin S (HbS)[1].

  • CAS Number: 2417955-18-9
  • MF: C20H22N2O6
  • MW: 386.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

11-O-syringylbergenin

11-O-Syringylbergenin is a bergenin derivative isolated from the whole plants of Corylopsis willmottiae Rehd. et Wils[1]

  • CAS Number: 126485-47-0
  • MF: C23H24O13
  • MW: 508.42900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d70 sodium

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery[1].

  • CAS Number: 326495-47-0
  • MF: C42H12D70NaO10P
  • MW: 871.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Umbelliferone 7-O-rutinoside

Umbelliferone 7-O-Rutinoside (Compound 9) is a natural product that can be isolated from the stems of Clausena emarginata[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eschweilenol C

Eschweilenol C is a compound derivative ellagic acid from the aqueous fraction of the ethanolic extract of Terminalia fagifolia Mart.[1].

  • CAS Number: 211371-02-7
  • MF: C20H16O12
  • MW: 448.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Tyr-OtBu

Boc-Tyr-OtBu is a tyrosine derivative[1].

  • CAS Number: 18938-60-8
  • MF: C18H27NO5
  • MW: 337.41100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 476.0±40.0°C
  • Melting Point: N/A
  • Flash Point: N/A

1-Hydroxyphenanthrene-d9

1-Hydroxyphenanthrene-d9 is a deuterium labeled compound.

  • CAS Number: 922510-23-4
  • MF: C14HD9O
  • MW: 203.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-methylumbelliferyl elaidate

4-methylumbelliferyl elaidate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 69003-01-6
  • MF: C28H40O4
  • MW: 440.61500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diethyl-amine-d10 Hydrochloride

Diethyl-amine-d10 (Hydrochloride) is the deuterium labeled Diethylamine hydrochloride[1].

  • CAS Number: 285132-87-8
  • MF: C4H2ClD10N
  • MW: 119.65900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 227-230ºC(lit.)
  • Flash Point: N/A

homatropine hydrochloride

Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1].

  • CAS Number: 637-21-8
  • MF: C16H22ClNO3
  • MW: 311.80
  • Catalog: mAChR
  • Density: N/A
  • Boiling Point: 403.3ºC at 760 mmHg
  • Melting Point: 226ºC
  • Flash Point: 197.7ºC

UVARIGRANOL C

Uvarigranol C, a polyoxygenated cyclohexene, is isolated from the stems of Uvaria boniana Finet. (Annonaceae)[1].

  • CAS Number: 172104-04-0
  • MF: C23H24O7
  • MW: 412.432
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 554.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 188.1±23.6 °C

Biotin-PEG23-amine

Biotin-nPEG-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

  • CAS Number: 604786-74-5
  • MF: C16H30N4O4S
  • MW: 770.972
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 870.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 480.2±34.3 °C