Lys-Ala-pNA is hydrolytic substrate the of dipeptidyl peptidase (DPP) II with Km of 0.42 mM[1].
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells[1].
H-Asp-Ala-OH is adipeptide.
Carboxybetaine methacrylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Navocaftor, as a cystic fibrosis transmembrane regulator (CFTR), is a protein modulator (US 20200377491 Al, example 1)[1].
N,N,N-Trimethylethanaminium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
CellTracker Green BODIPY (compound 31) is a green fluorescent dye that acts as an intracellular environmental tracer[1].
Beta-Acetoxyisovalerylshikonin is a naphthoquinone derivative isolated from Arnebia euchroma[1][2].
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine is a lysine derivative[1].
3-Pentadecylphenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
TrimethylvinylammoniumBromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Methyl nonacosanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
D-Allose-13C is the 13C labeled D-Allose. D-Allose is an endogenous metabolite[1].
N(im)-Trityl-L-histidine-propylamide is a histidine derivative[1].
3-Hydroxypicolinic acid is a picolinic acid derivative, and belongs to the pyridine family.
N-Acetyl-DL-histidine Monohydrate is a histidine derivative[1].
Tannase, also known as tanninyl hydrolase, is an enzyme that can hydrolyze ester bonds and tannic acid side bonds, releasing glucose and gallic acid, and is outstanding in clarifying wine and fruit juice[1].
Dimethyl trisulfide is an organic chemical compound and the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote[1].
Cyclomethicone can be used as an excipient, such as emollients, humectants, thickeners. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
Thialysine (hydrochloride) is a cysteine derivative[1].
HTHQ, which is a hydroquinone monoalkyl ether, is a potent anti-oxidative agent, even at low dose levels.HTHQ is found to be a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevated in biological systems, such as that of liver microsomes via the generation of stable free radicals. In vitro: HTHQ exhibits a similar anti-oxidative activity to that of D,L-alpha-tocopherol against lipid peroxidation in linolate micelles initiated by addition of Fe2+. HTHQ exhibits approximately 4.8-fold higher anti-lipid-peroxidation activity than that of D,L-alpha-tocopherol against the peroxidation in phosphatidylcholine liposomes initiated by addition of Fe2+. [1] up to 0.125% HTHQ significantly reduced the effects of 0.02% Glu-P-1 or 0.03% MeIQx on the number and area of foci. [2]In vivo: Treatment with HTHQ potently inhibits PhIP-induced mammary carcinogenesis in female rats without prior initiation treatment. . HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue. In this study, we showed that HTHQ improves against DMN-induced liver fibrosis in male SD rats.[3]
Phytanic acid methyl ester, an esterified form of long-chain fatty acid methyl esters and phytanic acid, has been found in Greek tobacco. 1 1. Kimland, B., Aasen, AJ and Enzell, CRTobacco chemistry. 10. Volatile neutral constituents of Hellenic Acta Tobacco Chemistry. Scand.26(6)2177-2184(1972)
1-Tridecanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM[1].
Hymexelsin (Xeroboside) is an apiose-containing scopoletin glycoside, that can be isolated from the stem bark of Hymenodictyon excelsum[1].
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (1O2) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of reactive oxygen species (ROS)[1][2].
Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism [1][2][3].
Sorafenib D3 (Bay 43-9006 D3) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
N-Valerylglycine is a Glycine (HY-Y0966) derivative[1].
Sodium naphthalen-1-yl hydrogenphosphate hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.