Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine

2’-Fluoro-2’-deoxy-N6-methylarabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 126502-12-3
  • MF: C11H14FN5O3
  • MW: 283.26
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2S)-2-Amino-3-(4-biphenylyl)propanoic acid

D-Biphenylalanine is a phenylalanine derivative[1].

  • CAS Number: 170080-13-4
  • MF: C15H15NO2
  • MW: 241.285
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 428.6±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 213.0±27.3 °C

PST2286

17α-Hydroxydigitoxigenin is an active small molecule[1].

  • CAS Number: 26629-41-4
  • MF: C23H34O5
  • MW: 390.51
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 588.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.5±23.6 °C

α,β-Trehalose-d2

α,β-Trehalose-d2 is the deuterium labeled α,β-Trehalose[1].

  • CAS Number: 2028292-29-5
  • MF: C12H20D2O11
  • MW: 344.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

fmoc-D-2-cyanophenylalanine

Fmoc-D-Phe(2-CN)-OH is a phenylalanine derivative[1].

  • CAS Number: 401620-74-4
  • MF: C25H20N2O4
  • MW: 412.437
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 666.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 356.6±31.5 °C

5-FAM-HIV-1 tat Protein (47-57) trifluoroacetate salt

TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research[1].

  • CAS Number: 1676104-81-6
  • MF: C85H128N32O20
  • MW: 1918.128
  • Catalog: HIV
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

butafenacil

Butafenacil (WC-9717; CGA-276854) is an herbicide that inhibits protoporphyrinogen oxidase[1].

  • CAS Number: 134605-64-4
  • MF: C20H18ClF3N2O6
  • MW: 474.815
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 539.4±60.0 °C at 760 mmHg
  • Melting Point: 113ºC
  • Flash Point: 280.0±32.9 °C

Beta-D-Glucopyranosyl nitromethane

Beta-D-Glucopyranosyl nitromethane, as a salt of a strongly basic anion exchanger in the OH cycle, is a glycosyl derivative of nitromethane[1].

  • CAS Number: 81846-60-8
  • MF: C7H13NO7
  • MW: 223.18100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lyso iGB3-d7

Lyso iGB3-d7 is deuterium labeled Lyso iGB3.

  • CAS Number: 2315262-49-6
  • MF: C36H60D7NO17
  • MW: 792.96
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DACN(Tos2,6-OH)

DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity[1].

  • CAS Number: 2109751-74-6
  • MF: C21H24N2O5S2
  • MW: 448.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2S)-Methyl 2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate

(2S)-Methyl 2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate is a valine derivative[1].

  • CAS Number: 402958-95-6
  • MF: C20H30N4O4
  • MW: 390.47700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Adenosine,N-2-propynyl- (9CI)

N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 67005-97-4
  • MF: C13H15N5O4
  • MW: 305.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.66g/cm3
  • Boiling Point: 679.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 364.7ºC

cypate

Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging[1][2].

  • CAS Number: 95837-47-1
  • MF: C41H40N2O4
  • MW: 624.76700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Brij-C20

Brij-C20 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 9004-95-9
  • MF: C56H114O21
  • MW: 1123.492
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 926.7±60.0 °C at 760 mmHg
  • Melting Point: 41-49ºC
  • Flash Point: 514.2±32.9 °C

Daphnetin dimethyl ether

7,8-Dimethoxycoumarin (Daphnetin dimethyl ether) is a coumarin from Artemisia caruifolia[1].

  • CAS Number: 2445-80-9
  • MF: C11H10O4
  • MW: 206.195
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 370.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 167.6±27.9 °C

LIPOPHILIC SEPHADEX

Sephadex LH 20 could be used for the isolation of natural compounds and food, such as red wine and pigments[1].

  • CAS Number: 9041-37-6
  • MF: C9H8N2O3S
  • MW: 224.23642
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diammonium phosphate

Diammonium phosphate is a neutral and efficient catalyst in 1,8‐Dioxo‐octahydroxanthene derivatives synthesis. Diammonium phosphate can be used as an excipient, such as diuretic, buffer, effervescent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 7783-28-0
  • MF: H9N2O4P
  • MW: 132.06
  • Catalog: Others
  • Density: 1.203 g/mL at 25 °C
  • Boiling Point: 158ºC at 760 mmHg
  • Melting Point: 155 °C (dec.)(lit.)
  • Flash Point: N/A

n-boc-n-[3-(boc-amino)propyl]glycine

N-tert-Butoxycarbonyl-N-[3-(tert-butoxycarbonylamino)propyl]glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 192124-66-6
  • MF: C15H28N2O6
  • MW: 332.39300
  • Catalog: Others
  • Density: 1.131g/cm3
  • Boiling Point: 472.958ºC at 760 mmHg
  • Melting Point: 120 °C
  • Flash Point: 239.837ºC

(2R,3R)-(-)-2,3-Butanediol

2,3-Butanediol is a butanediol derived from the bioconversion of natural resources[1].

  • CAS Number: 513-85-9
  • MF: C4H10O2
  • MW: 90.121
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 180.7±0.0 °C at 760 mmHg
  • Melting Point: 25 °C(lit.)
  • Flash Point: 85.0±0.0 °C

2-Bromo-1,4-difluorobenzene-d3

2-Bromo-1,4-difluorobenzene-d3 is the deuterium labeled 2-Bromo-1,4-difluorobenzene[1].

  • CAS Number: 1219795-54-6
  • MF: C6H3BrF2
  • MW: 192.989
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 155.4±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 65.0±0.0 °C

diethyl phthalate-d14

Diethyl phthalate-d14 is the deuterium labeled Diethyl phthalate[1].

  • CAS Number: 99873-99-1
  • MF: C12D14O4
  • MW: 236.32300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycine ethyl ester-13C2 hydrochloride

Glycine ethyl ester-13C2 (hydrochloride) is a 13C-labeled Propham[1].

  • CAS Number: 1246819-31-7
  • MF: C213C2H10ClNO2
  • MW: 141.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3,3-Trimethyl-2-norbornanone

(+)-Fenchone exists in fennel seed oil (Foenicufum vulgare Mill.) and in the oil of Lavandula stoechas. Fenchone is used as a flavor in foods and in perfumery[1].

  • CAS Number: 4695-62-9
  • MF: C10H16O
  • MW: 152.233
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 193.5±0.0 °C at 760 mmHg
  • Melting Point: 5-6ºC(lit.)
  • Flash Point: 69.3±10.7 °C

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC50 value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity[1].

  • CAS Number: 1608462-12-9
  • MF: C20H28O4
  • MW: 332.43392
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

l-4'-tetrahydropyranylglycine

(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 811842-25-8
  • MF: C7H13NO3
  • MW: 159.183
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 316.7±17.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 145.3±20.9 °C

Fenfangjine G

Fenfangjine G is an active component in Fangji Huangqi Tang (FHT). Fenfangjine G can be used for the research of nephrotic syndrome[1].

  • CAS Number: 205533-81-9
  • MF: C22H27NO8
  • MW: 433.452
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 625.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 332.2±31.5 °C

Sulfo-Cy5-Methyltetrazine

Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

  • CAS Number: 1801924-46-8
  • MF: C44H51N7O10S3
  • MW: 934.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pyridoxine dicaprylate

Pyridoxine Dicaprylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 106483-04-9
  • MF: C24H39NO5
  • MW: 421.57000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol

Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds[1][2][3].

  • CAS Number: 6918-48-5
  • MF: C17H35NO2
  • MW: 285.47
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 432.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 215.6±28.7 °C

PKC substrate (MBP)

[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].

  • CAS Number: 136132-68-8
  • MF: C60H100N20O17
  • MW: 1373.56000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A