Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Arachidin 2

Arachidin 2 is a antitoxins of plant origin[1].

  • CAS Number: 61517-87-1
  • MF: C19H20O3
  • MW: 296.36
  • Catalog: Others
  • Density: 1.216g/cm3
  • Boiling Point: 502.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 235.2ºC

MC-Ala-Ala-Asn-PAB-PNP

MC-Ala-Ala-Asn-PAB-PNP is a peptide, can be used to synthesize specifically activated micromolecular target coupling body[1].

  • CAS Number: 1638970-45-2
  • MF: C34H39N7O12
  • MW: 737.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ponasterone A

Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly[1][2].

  • CAS Number: 13408-56-5
  • MF: C27H44O6
  • MW: 464.635
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 640.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.2±28.0 °C

(S)-2-AMINO-3-METHOXY-PROPIONICACIDHYDROCHLORIDE

L-Allysine ethylene acetal is a lysine derivative[1].

  • CAS Number: 215054-80-1
  • MF: C8H15NO4
  • MW: 189.20900
  • Catalog: Others
  • Density: 1.208 g/cm3
  • Boiling Point: 338.72ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 158.653ºC

MELILOTOSIDE

trans-Melilotoside (compound 3) is a natural product that could be isolated form Mikania laevigata[1].

  • CAS Number: 618-67-7
  • MF: C15H18O8
  • MW: 326.29900
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-D-Phe-OH

Gly-d-Phe is an affinity ligand for Thermolysin (HY-P1748)[1]. Gly-d-Phe can be used as the substrate of membrane dipeptidase (MDP)[2].

  • CAS Number: 34258-14-5
  • MF: C11H14N2O3
  • MW: 222.24
  • Catalog: Others
  • Density: 1.259g/cm3
  • Boiling Point: 492.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 251.5ºC

Windaus Ketone

Windaus ketone is a VD building blocker.

  • CAS Number: 55812-80-1
  • MF: C19H32O
  • MW: 276.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,4-D methyl ester-d3

2,4-D methyl ester-d3 is the deuterium labeled Fmoc-Trp-OH[1].

  • CAS Number: 2732917-35-8
  • MF: C9H5D3Cl2O3
  • MW: 238.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mauritianin

Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor[1][2].

  • CAS Number: 109008-28-8
  • MF: C33H40O19
  • MW: 740.65900
  • Catalog: Topoisomerase
  • Density: 1.74g/cm3
  • Boiling Point: 1051ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 331.4ºC

1,3-Dimethoxybenzene

1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds[1].

  • CAS Number: 151-10-0
  • MF: C8H10O2
  • MW: 138.164
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 217.5±0.0 °C at 760 mmHg
  • Melting Point: -52°C
  • Flash Point: 87.8±0.0 °C

Fmoc-hLys(Boc)-OH

Fmoc-hLys(Boc)-OH is a lysine derivative[1].

  • CAS Number: 194718-17-7
  • MF: C27H34N2O6
  • MW: 482.56900
  • Catalog: Others
  • Density: 1.195±0.06 g/cm3(Predicted)
  • Boiling Point: 692.7±55.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

3-Methylvaline

2-Amino-3,3-dimethylbutanoic acid is a leucine derivative[1].

  • CAS Number: 33105-81-6
  • MF: C6H13NO2
  • MW: 131.173
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 217.7±23.0 °C at 760 mmHg
  • Melting Point: 299-301ºC
  • Flash Point: 85.5±22.6 °C

Octanoic acid,4-methylphenyl ester

p-Tolyl n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 59558-23-5
  • MF: C15H22O2
  • MW: 234.33400
  • Catalog: Others
  • Density: 0.95
  • Boiling Point: 175 °C / 12mmHg
  • Melting Point: N/A
  • Flash Point: 168 °C

Octocog alfa

Octocog alfa is a second-generation full-length recombinant factor VIII, as a antihemophilic factor[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-3-(2-Naphthyl)-L-alanine

Fmoc-2-Nal-OH is an alanine derivative[1].

  • CAS Number: 112883-43-9
  • MF: C28H23NO4
  • MW: 437.487
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 690.7±50.0 °C at 760 mmHg
  • Melting Point: 155ºC
  • Flash Point: 371.6±30.1 °C

1,12-Dibromododecane-d24

1,12-Dibromododecane-d24 is the deuterium labeled 1,12-Dibromododecane[1].

  • CAS Number: 1044544-84-4
  • MF: C12Br2D24
  • MW: 352.27500
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 362.8±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 180.2±18.2 °C

Ac-Arg-Gly-Lys(Ac)-MCA

Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC[1].

  • CAS Number: 660846-97-9
  • MF: C28H40N8O7
  • MW: 600.667
  • Catalog: HDAC
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TRV120055

TRV120055 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1].

  • CAS Number: 2410957-04-7
  • MF: C34H54N12O7
  • MW: 742.87
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Ala-OH

Fmoc-Ala-OH is an alanine derivative[1].

  • CAS Number: 35661-39-3
  • MF: C18H17NO4
  • MW: 311.332
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 544.1±33.0 °C at 760 mmHg
  • Melting Point: 150-154ºC
  • Flash Point: 282.9±25.4 °C

METTL3-IN-1

METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].

  • CAS Number: 2648257-77-4
  • MF: C25H24FN5O2
  • MW: 445.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ala-D-Glu(Lys-D-Ala-D-Ala-OH)-OH

Ala-D-γ-Glu-Lys-D-Ala-D-Ala is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala[1].

  • CAS Number: 2614-55-3
  • MF: C20H36N6O8
  • MW: 488.53500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Picropodophyllin 4-O-β-D-glucoside

Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants[1].

  • CAS Number: 1400-92-6
  • MF: C28H32O13
  • MW: 576.54600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cytidine 5'-Triphosphate ammonium salt-d8

Cytidine 5'-Triphosphate (ammonium salt)-d8 is the deuterium labeled Cytidine 5'-Triphosphate ammonium salt[1].

  • CAS Number: 2483831-66-7
  • MF: C9H20D8N7O14P3
  • MW: 559.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

s-butyrylthiocholine iodide

S-n-Butyrylthiocholine (iodide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 1866-16-6
  • MF: C9H20INOS
  • MW: 317.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 171-174 °C(lit.)
  • Flash Point: N/A

Devaleryl Valsartan Impurity

Devaleryl Valsartan Impurity is an intermediate in the synthesis of Valsartan[1].

  • CAS Number: 676129-92-3
  • MF: C19H21N5O2
  • MW: 351.402
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 598.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 315.6±32.9 °C

L-Mannitol

L-mannitol is a compound can be used for  the compound sweetener synthesis[1].

  • CAS Number: 643-01-6
  • MF: C6H14O6
  • MW: 182.17200
  • Catalog: Others
  • Density: 1.596 g/cm3
  • Boiling Point: 494.9ºC at 760 mmHg
  • Melting Point: 167 - 170ºC
  • Flash Point: 292.5ºC

Optovin

Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM).IC50 value:Target: in vitro: Optovin is a rhodanine-containing small molecule with no previously annotated biological activity. Whereas DMSO-treated animals do not respond to photic stimuli, optovin-treated animals respond to light with vigorous motor excitation at an EC50 of 2 μM. Optovin-treated animals respond to 387 nm (violet) stimuli, but not to 485 nm (blue), 560 nm (green) or longer wavelengths. optovin strongly activated 33% (35/105) of DRG neurons. optovin acts on a molecular target expressed in mustard oil responsive mammalian DRG sensory neurons; perhaps on TRPA1 itself. TrpA1 is necessary for the optovin response [1].in vivo: Optovin also elicited nociceptive behaviors in adult mice. optovin shows activity on adult animals in vivo, and may be preferable to conventional TRPA1 ligands for achieving high-resolution spatiotemporal control.

  • CAS Number: 348575-88-2
  • MF: C15H13N3OS2
  • MW: 315.413
  • Catalog: TRP Channel
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Abacavir-d4

rel-Abacavir-d4 is the deuterium labeled rel-Abacavir[1].

  • CAS Number: 1217731-56-0
  • MF: C14H14D4N6O
  • MW: 290.357
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 636.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 338.4±34.3 °C

PROTAC Linker 2

PROTAC Linker 2 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.

  • CAS Number: 1835705-52-6
  • MF: C21H41ClO4
  • MW: 393
  • Catalog: PROTAC Linker
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eosin Y

Eosin Y is a dye molecule. Eosin Y has low cost and good availability which has a wide application in organic synthesis as a photoredox catalyst[1].

  • CAS Number: 15086-94-9
  • MF: C20H8Br4O5
  • MW: 691.854
  • Catalog: Others
  • Density: 1.02 g/mL at 20ºC
  • Boiling Point: 640.3ºC at 760 mmHg
  • Melting Point: 295ºC
  • Flash Point: N/A