Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Phe(3-CN)-OH

H-Phe(3-CN)-OH is a phenylalanine derivative[1].

  • CAS Number: 57213-48-6
  • MF: C10H10N2O2
  • MW: 190.199
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 382.5±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.1±25.1 °C

2-[(2H5)Ethyloxy]phenol

2-Ethoxyphenol-d5 is the deuterium labeled 2-Ethoxyphenol[1].

  • CAS Number: 117320-30-6
  • MF: C8H5D5O2
  • MW: 143.195
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 219.4±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 91.1±0.0 °C

4-Aminophenyl 6-deoxy-α-L-mannopyranoside

4-Aminophenyl 6-deoxy-α-L-mannopyranoside is a glycoside that can be isolated from Camellia oleifera seeds.

  • CAS Number: 183878-99-1
  • MF: C12H17NO5
  • MW: 255.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

neohesperidose

Neohesperidose is a disaccharide isolated from species of typha[1].

  • CAS Number: 17074-02-1
  • MF: C12H22O10
  • MW: 326.29700
  • Catalog: Others
  • Density: 1.58g/cm3
  • Boiling Point: 713.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 268.2ºC

N1-Azido-spermine trihydrochloride

N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide.

  • CAS Number: 1823475-98-4
  • MF: C10H27Cl3N6
  • MW: 337.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beta-d-N4-hydroxycytidine

Beta-d-N4-hydroxycytidine is a very potent anti-VEEV (venezuelan equine encephalitis virus) agent with EC50, EC90, and EC99 are 0.426, 1.036, and 2.5 μM, respectively[1].

  • CAS Number: 3258-02-4
  • MF: C9H13N3O6
  • MW: 259.21600
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clerodenoside A

Clerodenoside A is a phenolic glycoside that can be extracted from the stem of Clerodendrum inerme[1].

  • CAS Number: 164022-75-7
  • MF: C35H44O17
  • MW: 736.71
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 872.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 267.6±27.8 °C

(Rac)-BCN-L-Lysine

(Rac)-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (Rac)-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

  • CAS Number: 1580501-90-1
  • MF: C17H26N2O4
  • MW: 322.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoxsuprine-monoester-1

Isoxsuprine-monoester-1, a monoester of isoxsuprine, is a long acting peripheral vasodilator.

  • CAS Number: 67160-74-1
  • MF: C23H31NO4
  • MW: 385.49700
  • Catalog: Cardiovascular Disease
  • Density: 1.096g/cm3
  • Boiling Point: 521.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 269.4ºC

Pueroside B

Pueroside B is an aromatic glycosidethat can be found in puerariae radix[1].

  • CAS Number: 100692-54-4
  • MF: C30H36O15
  • MW: 636.60
  • Catalog: Others
  • Density: 1.60±0.1 g/cm3(Predicted)
  • Boiling Point: 919.2±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

EPPTB

Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids[1][2].

  • CAS Number: 1110781-88-8
  • MF: C20H21F3N2O2
  • MW: 378.39
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Methyl-N-phenylglycine

N-Methyl-N-phenylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 40643-55-8
  • MF: C9H12ClNO2
  • MW: 201.65000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bimosiamose disodium

Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose disodium has anti-inflammatory effects[1].

  • CAS Number: 187269-60-9
  • MF: C46H52Na2O16
  • MW: 906.875
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.

  • CAS Number: 103476-24-0
  • MF: C6H9K6O15P3
  • MW: 648.638
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

V-11-0711

V-11-0711 (V-11 0711) is a novel potent and selective choline kinase alpha (ChoKα) inhibitor with IC50 of 20 nM, with 11 fold less activity against ChoKβ; exhibits excellent selectivity against a panel of 50 kinases; impedes the catalytic activity and causes a reversible growth arrest, reduces phosphocholine (Pcho) in Hela cells with IC50 of <1 uM; also shows synergetic cytotoxic effects combined with chemotherapeutic temozolomide in some cancer cell lines.

  • CAS Number: 1428339-47-2
  • MF: C27H35NO3
  • MW: 421.581
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PERFLUOROOCTYL BROMIDE

Perflubron(1-Bromoheptadecafluorooctane;Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Perflubron (1-Bromoheptadecafluorooctane;Heptadecafluorooctyl bromide; Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and shows exceptionally fast excretion characteristics[1][2].

  • CAS Number: 423-55-2
  • MF: C8BrF17
  • MW: 498.96200
  • Catalog: Others
  • Density: 1.93 g/mL at 25 °C(lit.)
  • Boiling Point: 142 °C(lit.)
  • Melting Point: 6 °C
  • Flash Point: 141-143°C

Padsevonil

Padsevonil is a potent antiepileptic agent.

  • CAS Number: 1294000-61-5
  • MF: C14H14ClF5N4O2S
  • MW: 432.797
  • Catalog: Neurological Disease
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Pentadecanol

1-Pentadecanol is a naturally occurring antiacne agent[1].

  • CAS Number: 629-76-5
  • MF: C15H32O
  • MW: 228.414
  • Catalog: Inflammation/Immunology
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 298.5±3.0 °C at 760 mmHg
  • Melting Point: 41-44 °C(lit.)
  • Flash Point: 130.1±4.6 °C

UDP-α-D-N-Acetylglucosamine Disodium Salt

UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).

  • CAS Number: 91183-98-1
  • MF: C17H25N3Na2O17P2
  • MW: 651.31700
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

UNII:JR71SUM5E9

2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity[1].

  • CAS Number: 100-72-1
  • MF: C6H12O2
  • MW: 116.158
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 183.9±8.0 °C at 760 mmHg
  • Melting Point: 187°C
  • Flash Point: 93.3±0.0 °C

6-((7-NITROBENZO[C][1,2,5]OXADIAZOL-4-YL)AMINO)HEXANOIC ACID

NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions[1].

  • CAS Number: 88235-25-0
  • MF: C12H14N4O5
  • MW: 294.26300
  • Catalog: Others
  • Density: 1.462
  • Boiling Point: 559.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

sucrose

Sucrose is a disaccharide which is composed of two monosaccharides, glucose and fructose.

  • CAS Number: 57-50-1
  • MF: C12H22O11
  • MW: 342.297
  • Catalog: Metabolic Disease
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 697.1±55.0 °C at 760 mmHg
  • Melting Point: 185-187 °C(lit.)
  • Flash Point: 375.4±31.5 °C

Kaji-ichigoside F1

Kaji-ichigoside F1 is isolated from S. cuneata with hemolytic and in vitro antiviral activity.[1]

  • CAS Number: 95298-47-8
  • MF: C36H58O10
  • MW: 650.840
  • Catalog: Infection
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 741.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 223.6±26.4 °C

Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2

Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 is a L-Lysine (HY-N0469) derivative[1].

  • CAS Number: 396665-80-8
  • MF: C81H126N20O26S
  • MW: 1828.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Andropanoside

Andropanoside is a natural product isolated and purified from the herbs of Andrographis paniculata. Andrographis paniculata possesses a protective activity against various liver disorders[1].

  • CAS Number: 82209-72-1
  • MF: C26H40O9
  • MW: 496.590
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 704.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232.7±26.4 °C

H-Gly-Gly-Ala-OH

Glycylglycylalanine is a biologically active peptide.

  • CAS Number: 19729-30-7
  • MF: C7H13N3O4
  • MW: 203.19600
  • Catalog: Others
  • Density: 1.314 g/cm3
  • Boiling Point: 604.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 319.5ºC

SALMFamide 1

SALMF amide 1 is a neuropeptide[1].

  • CAS Number: 134439-73-9
  • MF: C41H60N10O10S
  • MW: 885.04100
  • Catalog: Neurological Disease
  • Density: 1.282g/cm3
  • Boiling Point: 1388.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 793.6ºC

2-Methylanisole-d3

2-Methylanisole-d3 is the deuterium labeled 2-Methylanisole[1]. 2-Methylanisole is a monomethoxybenzene and acts as an intermediate for the preparation of compounds with methylhydroquinone core[2].

  • CAS Number: 258832-47-2
  • MF: C8H7D3O
  • MW: 125.183
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 171.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 51.7±0.0 °C

Liriope muscari baily saponins C

Liriope muscari baily saponins C is one of major active compounds of L. muscari (Decne.) Baily. Liriope muscari baily saponins C possesses strong anti-inflammatory, immunopharmacological and cardioprotective activities. Liriope muscari baily saponins C has been studied as a candidate drug for cancer metastasis[1].

  • CAS Number: 87480-46-4
  • MF: C44H70O16
  • MW: 855.017
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-5,7,4'-Trimethoxyafzelechin

(+)-5,7,4'-Trimethoxyafzelechin is a derivative of (+)-Afzelechin HY-N2821. (+)-Afzelechin is an α-glucosidase activity inhibitor. (+)-Afzelechin can be isolated from rhizomes of Bergenia ligulata[1].

  • CAS Number: 918428-88-3
  • MF: C18H20O5
  • MW: 316.348
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 502.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 257.9±30.1 °C