Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Trp-Met-OH

H-Trp-Met-OH is a biologically active peptide.

  • CAS Number: 21438-63-1
  • MF: C16H21N3O3S
  • MW: 335.42100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2,3,7-tetramethoxyxanthone

1,2,3,7-Tetramethoxyxanthone is a xanthone isolated from Polygala tenuifolia[1].

  • CAS Number: 22804-52-0
  • MF: C17H16O6
  • MW: 316.30500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxy-1-tetralone

5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples[1].

  • CAS Number: 28315-93-7
  • MF: C10H10O2
  • MW: 162.185
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 325.3±31.0 °C at 760 mmHg
  • Melting Point: 206-209 °C(lit.)
  • Flash Point: 138.1±17.4 °C

Boc-O-benzyl-D-threonine

Boc-D-Thr(Bzl)-OH is a threonine derivative[1].

  • CAS Number: 69355-99-3
  • MF: C16H23NO5
  • MW: 309.358
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 461.5±45.0 °C at 760 mmHg
  • Melting Point: 110-117ºC
  • Flash Point: 232.9±28.7 °C

Benzenepentacarboxylic Acid

Benzenepentacarboxylic acid (BA), a novel fluorescent probeas to detect and scavenge HO-.A specific and reproducible fluorescent probe of HO- developed is utilized to prove and detect the generation of HO- in H2O2/TAED and H2O2/TBCC alkali systems.

  • CAS Number: 1585-40-6
  • MF: C11H6O10
  • MW: 298.15900
  • Catalog: Dye Reagents
  • Density: 1.96g/cm3
  • Boiling Point: 642.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 356.3ºC

(±)-Abscisic acid

(±)-Abscisic acid is an orally active plant hormone that is present also in animals. (±)-Abscisic acid (ABA) contributes to the regulation of glycemia in mammals[1].

  • CAS Number: 14375-45-2
  • MF: C15H20O4
  • MW: 264.317
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 458.7±45.0 °C at 760 mmHg
  • Melting Point: 186-188 °C(lit.)
  • Flash Point: 245.4±25.2 °C

2-Nitrobenzaldehyde semicarbazone 13C,15N2

2-Nitrobenzaldehyde semicarbazone 13C,15N2 is used for analysis of semicarbazide in the LC-MS/MS method[1].

  • CAS Number: 760179-80-4
  • MF: 13CC7H815N2N2O3
  • MW: 211.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cinnamyl caffeate

Cinnamyl caffeate is a caffeic acid ester that can be isolated from Slovenian Propolis[1].

  • CAS Number: 115610-32-7
  • MF: C18H16O4
  • MW: 296.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ulmoidol

Ulmoidol prevents neuroinflammation by targeting the PU.1 transcriptional signaling pathway.

  • CAS Number: 196093-13-7
  • MF: C29H42O5
  • MW: 470.64
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium inner salt

NMP-ACA is an impurity of Cefepime. Cefepime is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria[1].

  • CAS Number: 103296-32-8
  • MF: C13H19N3O3S
  • MW: 297.37300
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 1059182-21-6
  • MF: C20H24O8
  • MW: 392.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate

Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1035404-17-1
  • MF: C19H20ClNO4
  • MW: 361.81900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ALV2

ALV2 is a potent and selective Helios degrader. ALV2 binds CRBN, with an IC50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable Treg cell phenotype in the inflammatory tumor microenvironment[1].

  • CAS Number: 2438124-95-7
  • MF: C26H26ClN5O5
  • MW: 523.97
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Bromobenzoic acid-d4

2-Bromobenzoic acid-d4 is the deuterium labeled 2-Bromobenzoic acid[1].

  • CAS Number: 2133385-73-4
  • MF: C7HD4BrO2
  • MW: 205.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(α,β,β,2,3,5,6-2H7)Tyrosine

DL-Tyrosine-d7 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].

  • CAS Number: 402835-78-3
  • MF: C9H4D7NO3
  • MW: 188.23
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 385.2±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 186.7±25.1 °C

Fulvestrant 3-β-D-Glucuronide

Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer[1].

  • CAS Number: 261506-27-8
  • MF: C38H55F5O9S
  • MW: 782.895
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 863.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 475.8±34.3 °C

TAPSO

TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5–9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides[1].

  • CAS Number: 68399-81-5
  • MF: C7H17NO7S
  • MW: 259.277
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 224-229 °C (dec.)
  • Flash Point: N/A

SiR-COOH

SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm)[1].

  • CAS Number: 1418275-26-9
  • MF: C27H28N2O4Si
  • MW: 472.61
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethidium bromide

Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

  • CAS Number: 1239-45-8
  • MF: C21H20BrN3
  • MW: 394.308
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 260-262 °C (dec.)(lit.)
  • Flash Point: >100°C

Fmoc-D-Phg-OH

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 111524-95-9
  • MF: C23H19NO4
  • MW: 373.401
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 606.3±50.0 °C at 760 mmHg
  • Melting Point: 176 °C(dec.)
  • Flash Point: 320.5±30.1 °C

Imidazol-1-yl compound 1

Imidazol-1-yl compound 1 is a compound which can be used to treat gastro intestinal functional disorders in the lower intestinal tracts extracted from patent DE 4238553 A1.

  • CAS Number: 120635-47-4
  • MF: C20H21N3O
  • MW: 319.40000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium formate-13C,d1

Sodium formate-13C,d1 is the deuterium and 13C labeled Sodium formate[1].

  • CAS Number: 1215684-17-5
  • MF: 13CHDNaO2
  • MW: 71.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16-O-Methylcafestol

16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans[1].

  • CAS Number: 108214-28-4
  • MF: C21H30O3
  • MW: 330.46100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-(Trifluoromethyl)-L-phenylglycine

4-(Trifluoromethyl)-L-phenylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 144789-75-3
  • MF: C9H8F3NO2
  • MW: 219.16100
  • Catalog: Others
  • Density: 1.415 g/cm3
  • Boiling Point: 297.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 133.6ºC

Apafant

Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM[1].

  • CAS Number: 105219-56-5
  • MF: C22H22ClN5O2S
  • MW: 455.96
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 720.2±70.0 °C at 760 mmHg
  • Melting Point: 186-188ºC
  • Flash Point: 389.4±35.7 °C

RCB16007

RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM)[1].

  • CAS Number: 2952530-26-4
  • MF: C18H14ClN5O2S
  • MW: 399.85
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoscoparin

Isoscoparin is a flavonoid that could be isolated from EtOAc extract of Gentiana algida Pall. Isoscoparin possesses antioxidant activity[1].

  • CAS Number: 20013-23-4
  • MF: C22H22O11
  • MW: 462.40300
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: 818.6±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Ethane-1,2-diamine dihydrochloride-13C2

Ethane-1,2-diamine dihydrochloride-13C2 is the 13C labeled Ethane-1,2-diamine dihydrochloride[1].

  • CAS Number: 77435-60-0
  • MF: C2H10Cl2N2
  • MW: 135.00600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chloroacetyl-dl-norleucine

N-Chloroacetyl-DL-norleucine is a leucine derivative[1].

  • CAS Number: 67206-26-2
  • MF: C8H14ClNO3
  • MW: 207.65500
  • Catalog: Others
  • Density: 1.2g/cm3
  • Boiling Point: 409.6ºC at 760 mmHg
  • Melting Point: 113ºC
  • Flash Point: 201.5ºC

Rotundatin

Rotundatin is useful in inhibition of the aggregation of platelets induced by arachidonic acid and collagen[1].

  • CAS Number: 144506-16-1
  • MF: C15H14O4
  • MW: 258.27
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A