Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

poly (arginyl-glycyl-aspartyl-threonine)

RGDT is a synthetic peptide. RGDT can be used in the research of cancer[1][2].

  • CAS Number: 93675-01-5
  • MF: C10H12AsNO6
  • MW: 317.127
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

γ-Glutamyl-S-1-propenyl cysteine

γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic[1].

  • CAS Number: 91216-96-5
  • MF: C11H18N2O5S
  • MW: 290.34
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raloxifene 6,4'-Bis-β-D-glucuronide

Raloxifene 6,4'-Bis-β-D-glucuronide (compound IV) is a metabolite of Raloxifene. Raloxifene is a selective estrogen receptor antagonist for the prevention of osteoporosis[1].

  • CAS Number: 182507-20-6
  • MF: C40H43NO16S
  • MW: 827.84700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[Asu1,6]-Oxytocin

[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].

  • CAS Number: 14317-68-1
  • MF: C45H69N11O12
  • MW: 956.09600
  • Catalog: Metabolic Disease
  • Density: 1.216g/cm3
  • Boiling Point: 1475.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 846ºC

1,3-Dibromo-1,3-dichloroacetone

1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant[1].

  • CAS Number: 62874-84-4
  • MF: C3H2Br2Cl2O
  • MW: 284.76100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

11-Deoxymogroside V

11-Deoxymogroside V is a cucurbitane triterpene glycoside[1].

  • CAS Number: 1707161-17-8
  • MF: C60H102O28
  • MW: 1271.435
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(22R)-2β,3β,20,22,25-Pentahydroxy-5β-cholesta-8,14-dien-6-one

Podecdysone B is a phytoecdysone isolated from Cyanotis arachnoidea[1].

  • CAS Number: 22612-27-7
  • MF: C27H42O6
  • MW: 462.61900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

2-O-β-D-Glucosyloxy-4-methoxybenzene propanoic acid is a glucoside derivative[1].

  • CAS Number: 477873-63-5
  • MF: C16H22O9
  • MW: 358.34
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 624.6±55.0 °C at 760 mmHg
  • Melting Point: 168-169℃ (acetone )
  • Flash Point: 228.0±25.0 °C

(E)-3-(4-Methoxyphenyl)acrylic acid

(E)-3-(4-Methoxyphenyl)acrylic acid (compound 3) is isolated from Arachis hypogaea, Scrophularia buergeriana Miquel, Aquilegia vulgaris, Anigozanthos preissii and so on. (E)-3-(4-Methoxyphenyl)acrylic acid shows significant hepatoprotective activity, anti-amnesic, cognition-enhancing activity, antihyperglycemic, and neuroprotective activities[1].

  • CAS Number: 943-89-5
  • MF: C10H10O3
  • MW: 178.185
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 342.6±17.0 °C at 760 mmHg
  • Melting Point: 173.5ºC
  • Flash Point: 138.6±14.4 °C

3,3'-Dioctadecyloxacarbocyanine perchlorate

3,3′-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent lipophilic tracer, which is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes.

  • CAS Number: 34215-57-1
  • MF: C53H85ClN2O6
  • MW: 881.70500
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(2,6-Dimethylphenyl)-1-isopropylpiperidine-2-carboxamide-d7

N-(2,6-Dimethylphenyl)-1-isopropylpiperidine-2-carboxamide-d7 is the deuterium labeled N-(2,6-dimethylphenyl)-1-isopropylpiperidine-2-carboxamide[1].

  • CAS Number: 1276197-11-5
  • MF: C17H19D7N2O
  • MW: 281.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Valylglutamic acid

Valylglutamic acid is a biologically active peptide.

  • CAS Number: 3062-07-5
  • MF: C10H18N2O5
  • MW: 246.26000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CD22 ligand-1

CD22 ligand-1 (compound 12) is a potent and selective CD22 ligand with KD of 0.335, 30.7 µM for hCD22 and MAG, respectively. CD22 ligand-1 has the potential for the research of B-cell related disease[1].

  • CAS Number: 2493080-27-4
  • MF: C33H34N5NaO10
  • MW: 683.64
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TP748

TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines[1].

  • CAS Number: 951698-15-0
  • MF: C15H18N2O2
  • MW: 258.316
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 367.3±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 176.0±27.9 °C

24-Hydroxy-licorice-saponin A3

24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis.[1].

  • CAS Number: 1262326-47-5
  • MF: C48H72O22
  • MW: 1001.072
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1107.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 316.0±27.8 °C

Bz-RGFFP-4MβNA

Bz-RGFFP-4MβNA, a substrate for Cathepsin D, is suitable for either colorimetric or fluorometric assay[1].

  • CAS Number: 782432-03-5
  • MF: C49H55N9O7
  • MW: 882.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

25S-Inokosterone

25S-Inokosterone is a phytoecdysone in the roots of two same species of A. bidentata Blume and A. japonica Nakai, and two different species of C. capitata Moq and C. officinalis Kuan. 25S-Inokosterone has the potential for the LPS-induced acute kidney injury research[1][2].

  • CAS Number: 19595-18-7
  • MF: C27H44O7
  • MW: 480.63400
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-O2Oc-O2Oc-OH

N3-O2Oc-O2Oc-OH is a click chemistry reagent containing an azide[1].

  • CAS Number: 1254054-60-8
  • MF: C12H22N4O7
  • MW: 334.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-L-Tyr(2-azidoethyl)-OH

Boc-L-Tyr(2-azidoethyl)-OH (N-Boc-O-(2-azidoethyl)-L-tyrosine) is a click chemistry reagent containing an azide group[1].

  • CAS Number: 1434445-10-9
  • MF: C16H22N4O5
  • MW: 350.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium formononetin-3'-sulfonate

Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol. derivate of formononetin. IC50 value:Target: Research results showed that treatment with Sul-F significantly prevented the elevation of ST-segment level, decreased the contents of creatine kinase-MB, lactate dehydrogenase, alanine aminotransferase and cardiac troponin T in serum and reduced the myocardium necrosis scores. These findings indicate that Sul-F has a protective potential against myocardial infarction injury. A possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defense enzymes degraded lipid peroxidn. products and improved energy metab. of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. Other reaearch results showed that sodium formononetin-3'-sulfonate not only had favorable water, solubility but also had good lipid-lowering and liver-protection activities.

  • CAS Number: 949021-68-5
  • MF: C16H11NaO7S
  • MW: 370.31
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Carnitine(mono)-O-glutaryl-d3 perchlorate

L-Carnitine(mono)-O-glutaryl-d3 (perchlorate) is the deuterium labeled L-Carnitine(mono)-O-glutaryl (perchlorate)[1].

  • CAS Number: 2245711-21-9
  • MF: C12H19D3ClNO10
  • MW: 378.78
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β)-3-Hydroxyurs-12-en-30-oic acid

Dulcioic acid (compound 19) is a product isolated from Tripterygium wilfordii Hook f. Dulcioic acid shows a significant inhibitory effect on cytokine production[1].

  • CAS Number: 78516-69-5
  • MF: C30H48O3
  • MW: 456.70
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 556.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.1±26.6 °C

H-D-Val-OtBu.HCl

H-D-Val-OtBu.HCl is a valine derivative[1].

  • CAS Number: 104944-18-5
  • MF: C9H20ClNO2
  • MW: 209.714
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 144-146ºC
  • Flash Point: N/A

Lutein myristate palmitate

Lutein myristate palmitate is a terpenoid compound isolated from Tagetes patula[1].

  • CAS Number: 104784-49-8
  • MF: C70H112O4
  • MW: 1017.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-(carboxymethylamino)-2-methyl-3-oxopropanoic acid

(±)-N-Methylmalonylglycine is a synthetic amino acid.

  • CAS Number: 63942-67-6
  • MF: C6H9NO5
  • MW: 175.13900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Anemarrhenasaponin Ia

Anemarrhenasaponin Ia, isolated from Anemarrhenae rhizome, inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Anemarrhenasaponin Ia is an useful anti-inflammation reagent[1].

  • CAS Number: 221317-02-8
  • MF: C48H68O14
  • MW: 772.96
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sucralfate

Sucralfate is a cytoprotective agent which has been employed for prevention and treatment of several gastrointestinal diseases.

  • CAS Number: 54182-58-0
  • MF: C12H14Al16O75S8
  • MW: 2046.42
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1′-Disinomenine

1,1′-Disinomenine is an alkaloid that can be isolated from the stems of Sinomenium acutum. 1,1′-Disinomenine shows weak inhibition against A549 and Hela cells[1].

  • CAS Number: 596-58-7
  • MF: C38H44N2O8
  • MW: 656.76
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sepofarsen

Sepofarsen (QR-110) is an RNA antisense oligonucleotide targeting to the p.Cys998X mutation (also known as the c.2991+1655A>G mutation) in the CEP290 gene.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-medicarpin

Isomedicarpin is a natural product that can be found in Erythrina[1].

  • CAS Number: 74560-05-7
  • MF: C16H14O4
  • MW: 270.28
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 418.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.1±28.7 °C