Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Octotiamine

Octotiamine (TATD) is a vitamin B1 analogue, a component of vitamin complex. Octotiamine can be used for the research of vitamin B1 deficiency[1].

  • CAS Number: 137-86-0
  • MF: C23H36N4O5S3
  • MW: 544.75100
  • Catalog: Others
  • Density: 1.268g/cm3
  • Boiling Point: 722ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 390.5ºC

Methyl (2H31)hexadecanoate

Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].

  • CAS Number: 29848-79-1
  • MF: C17H3D31O2
  • MW: 301.64
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 332.1±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 152.8±7.5 °C

6alpha-Hydroxytomentosin

6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines[1][2].

  • CAS Number: 1232676-22-0
  • MF: C15H20O4
  • MW: 264.317
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jatrorrhizine Hydrochloride

Jatrorrhizine chloride is a potent and orally active uptake-2 transporter inhibitor, it can be isolated from various Chinese medicinal plants[1]. Jatrorrhizine chloride exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of MAPK pathway in HT22 hippocampal neurons[2].

  • CAS Number: 6681-15-8
  • MF: C20H20ClNO4
  • MW: 374.83800
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Xipamide-d6

Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1][2].

  • CAS Number: 1330262-09-3
  • MF: C15H9ClD6N2O4S
  • MW: 360.84600
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

agrimonolide-6-O-glucopyranoside

Agrimonolide 6-O-β-D-glucoside is a isocoumarin that can be isolated from Agrimonia pilosa. Agrimonolide 6-O-β-D-glucoside is used in hepatic disease research[1].

  • CAS Number: 126223-29-8
  • MF: C24H28O10
  • MW: 476.47
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 807.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.7±27.8 °C

Tridecane

Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound[1][2].

  • CAS Number: 629-50-5
  • MF: C13H28
  • MW: 184.36100
  • Catalog: Others
  • Density: 0.756 g/mL at 25 °C(lit.)
  • Boiling Point: 110-112 °C12 mm Hg(lit.)
  • Melting Point: −6-−4 °C(lit.)
  • Flash Point: 215 °F

Hispolon

Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities[1].

  • CAS Number: 173933-40-9
  • MF: C12H12O4
  • MW: 220.221
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 477.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 256.5±25.2 °C

B8R 20-27

B8R 20-27 is a biological active peptide. (This is amino acids 20 to 27 fragment of B8R, a vaccinia virus (VV) gene that encodes a secreted protein related to gamma interferon receptor. B8R binding to IFN-g neutralizes its antiviral activity.)

  • CAS Number: 848642-31-9
  • MF: C44H65N9O15
  • MW: 960.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Carcinoembryonic Antigen CEA

Carcinoembryonic antigen (CEA) is a tumor marker in lung cancer.

  • CAS Number: 168635-85-6
  • MF: C43H68N10O15
  • MW: 965.08
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-BENZYLOXYBENZALDEHYDE-α-D1

3-Benzyloxybenzaldehyde-α-d1 is the deuterium labeled 3-Benzyloxybenzaldehyde[1].

  • CAS Number: 1219805-34-1
  • MF: C14H11DO2
  • MW: 213.25000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ribocil-C

Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.

  • CAS Number: 1825355-56-3
  • MF: C21H21N7OS
  • MW: 419.503
  • Catalog: Infection
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 672.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 360.2±34.3 °C

Ataprost

Ataprost (ONO 41483) is an orally active Carboprostacyclin (HY-112322) analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm[1].

  • CAS Number: 83997-19-7
  • MF: C21H32O4
  • MW: 348.47600
  • Catalog: Cardiovascular Disease
  • Density: 1.255g/cm3
  • Boiling Point: 529.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 288.3ºC

MAGE-3 Antigen (167-176) (human) acetate salt

MAGE-3 Antigen (167-176) (human) is a polypeptide containing eight amino acids. MAGE-3 Antigen (167-176) (human) is a human leukocyte antigen HLA-B44 molecules epitope encoded by melanoma antigen gene (MAGE)[1].

  • CAS Number: 178243-46-4
  • MF: C53H80N12O16S
  • MW: 1173.338
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1588.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 914.6±34.3 °C

Hosenkoside F

Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.

  • CAS Number: 160896-45-7
  • MF: C47H80O19
  • MW: 949.127
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1045.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 585.9±34.3 °C

11-Oxo-α-amyrin

11-Oxo-α-amyrin (Neoilexonol) is a triterpenoid that can be isolated from Leonurus japonicus (Lamiaceae)[1].

  • CAS Number: 2118-90-3
  • MF: C30H48O2
  • MW: 440.70
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don[1].

  • CAS Number: 164022-74-6
  • MF: C23H22O12
  • MW: 490.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,3',4',5,6,7,8-heptamethoxyflavone

3,5,6,7,8,3',4'-heptamethoxyflavone, a flavonoid in C. unshiu peels, exhibits anti-tumor-initiating effect and Anti-neuroinflammatory activity[1][2][3]. 3,5,6,7,8,3',4'-heptamethoxyflavone inhibits collagenase activity and increased type I procollagen content in HDFn cells[1]. 3,5,6,7,8,3',4'-heptamethoxyflavone induces brain-derived neurotrophic factor (BDNF) expression via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells[4].

  • CAS Number: 1178-24-1
  • MF: C22H24O9
  • MW: 432.421
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 618.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 268.0±31.5 °C

Boc-D-Phe(3,4-Cl2)-OH

(R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dichlorophenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 114873-13-1
  • MF: C14H17Cl2NO4
  • MW: 334.195
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 478.1±45.0 °C at 760 mmHg
  • Melting Point: 120ºC
  • Flash Point: 242.9±28.7 °C

5-Valine-angiotensin I

5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2].

  • CAS Number: 484-43-5
  • MF: C61H87N17O14
  • MW: 1282.45000
  • Catalog: Cardiovascular Disease
  • Density: 1.44g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Labda-8(20),14-dien-13-ol, (13S)

13-Epimanool is the compound isolated from the bark of the Taiwan hemlock[1].

  • CAS Number: 1438-62-6
  • MF: C20H34O
  • MW: 290.48
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 368.2±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 118.2±15.6 °C

AH1 is an immunodominant antigen derived from the gp70 product of an endogenous MuLV. AH1 behaves as the CTL-immunodominant epitope of CT26 colon carcinoma[1][2].

  • CAS Number: 181272-91-3
  • MF: C54H70N12O15
  • MW: 1127.20000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SLEC-11

SLEC-11 acts as a potential synthetic lethal lead for the treatment of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1-/-[1].

  • CAS Number: 863761-17-5
  • MF: C18H17FN2O
  • MW: 296.34
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tolazamide

Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes.

  • CAS Number: 1156-19-0
  • MF: C14H21N3O3S
  • MW: 311.40000
  • Catalog: Endocrinology
  • Density: 1.29g/cm3
  • Boiling Point: 289 °C772 mm Hg(lit.)
  • Melting Point: 171-173 °C(lit.)
  • Flash Point: 100 °C

Steviol-​19-​O-​glucoside

Steviol-​19-​O-​glucoside is a metabolite of steviol in the steviol glycosides biosynthesis pathway in Stevia rebuadiana[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetyl-Octreotide

Acetyl-octreotide is a reduced linear peptide. Acetyl-octreotide can synthesize Re(V)-cyclized peptides in aqueous methanol solutions with low Sst receptor binding affinities[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Furimazine

Furimazine is an imidazopyrazinone substrate. NanoLuc (Nluc) paired with Furimazine produced 2.5 million-fold brighter luminescence in mammalian cells relative to Oluc-19 with Coelenterazine.

  • CAS Number: 1374040-24-0
  • MF: C24H19N3O2
  • MW: 381.43
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DMT-2'Fluoro-DG(IB) Amidite

DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine[1].

  • CAS Number: 144089-97-4
  • MF: C44H53FN7O8P
  • MW: 857.906
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ile-His-OH

H-Ile-His-OH is a biologically active peptide.

  • CAS Number: 97284-12-3
  • MF: C12H20N4O3
  • MW: 268.312
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 603.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 319.0±31.5 °C

NADA-green

NADA-green, a fluorescent D-amino acid, suitable for labeling peptidoglycans in live bacteria. NADA-green is incorporated into bacterial cell walls during synthesis. NADA-green results in strong peripheral and septal labeling of taxonomically diverse bacterial cell populations without affecting growth rate. Excitation/emission λ ~450/555 nm.

  • CAS Number: 2253733-11-6
  • MF: C9H10ClN5O5
  • MW: 303.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A