Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Limocitrin 3-O-beta-D-glucopyranoside

Limocitrin 3-β-D-glucose is a flavonoid glycoside[1].

  • CAS Number: 38836-51-0
  • MF: C23H24O13
  • MW: 508.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pitnot-2

Pitnot-2 is an inactive analog of clathrin inhibitor Pitstop 2. Pitnot-2 can be used as negative control[1].

  • CAS Number: 1576239-29-6
  • MF: C20H13BrN2OS
  • MW: 409.30
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzothioamide-d5

Benzothioamide-d5 is the deuterium labeled Benzothioamide[1].

  • CAS Number: 1219804-59-7
  • MF: C7H2D5NS
  • MW: 142.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganolucidic acid A

Ganolucidic acid A is a natural product that can be isolated from Ganoderma lucidum[1].

  • CAS Number: 98665-21-5
  • MF: C30H44O6
  • MW: 500.66700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Minzasolmin

Minzasolmin is an alpha-synuclein oligomerization inhibitor[1].

  • CAS Number: 1802518-92-8
  • MF: C23H31N5OS
  • MW: 425.59
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

R-Notoginsenoside R2

20(R)-Notoginsenoside R2 is an isolated notoginsenoside from Panax notoginseng[1].

  • CAS Number: 948046-15-9
  • MF: C41H70O13
  • MW: 770.987
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 878.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 485.2±34.3 °C

2,4,6-Tris[(2H3)methyl](2H2)phenol

2,4,6-Trimethylphenol-d11 is the deuterium labeled 2,4,6-Trimethylphenol[1]. 2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter (3DOM*). 2,4,6-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution[2][3].

  • CAS Number: 362049-45-4
  • MF: C9HD11O
  • MW: 147.259
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 215.8±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 96.7±8.4 °C

Myt1-IN-3

Myt1-IN-3 is a potent Myt1 inhibitor with an IC50s of <10 nM (WO2021195782 A1, compound 95)[1].

  • CAS Number: 2719793-54-9
  • MF: C18H19N5O2
  • MW: 337.38
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Chlorthal-dimethyl-d6

Chlorthal-dimethyl-d6 is the deuterium labeled Chlorthal-dimethyl[1].

  • CAS Number: 350818-66-5
  • MF: C10Cl4D6O4
  • MW: 338.00100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Leu8,D-Trp22,Tyr25)-Somatostatin-28

[Leu8,D-Trp22,Tyr25] Somatostatin-28 is the analog of Somatostatin-28. Somatostatin-28 is a intestinal peptide containing somatostatin in its C-terminal portion[1][2].

  • CAS Number: 77909-99-0
  • MF: C138H209N41O40S2
  • MW: 3146.517
  • Catalog: Neurological Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jacobine

Jacobine is a pyrrolizidine alkaloid (PA) from Senecio jacobaea[1]. Jacobine is active against second instar larvae of thrips[2].

  • CAS Number: 6870-67-3
  • MF: C18H25NO6
  • MW: 351.39400
  • Catalog: Others
  • Density: 1.33g/cm3
  • Boiling Point: 574.1ºC at 760 mmHg
  • Melting Point: 228ºC
  • Flash Point: 301ºC

Dihydrolanosterol

Dihydrolanosterol is a subtrate of CYP51 and a cholesterol biosynthesis inhibitor.[1].

  • CAS Number: 79-62-9
  • MF: C30H52O
  • MW: 428.73
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

VUAA1

VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research[1][2].

  • CAS Number: 525582-84-7
  • MF: C19H21N5OS
  • MW: 367.46800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Hydroxy-4-cadinen-3-one

9β-Hydroxy-ageraphorone is a natural cadinene sesquiterpene compound[1].

  • CAS Number: 97372-53-7
  • MF: C15H24O2
  • MW: 236.35
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 356.7±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 152.1±20.5 °C

SB 657510

SB-657510 is a selective urotensin II (UII) receptor (UT) antagonist. The Ki values are 61, 17, 30, 65 and 56 nM for human, monkey, cat, rat and mouse receptors, respectively. SB-657510 exerts anti-inflammatory effects by inhibiting UII-induced upregulation of inflammatory mediators such as adhesion molecules, cytokines, and tissue factor in human vascular endothelial cells[1][2].

  • CAS Number: 474960-44-6
  • MF: C19H22BrClN2O5S
  • MW: 505.81000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-trans-5-Methyl-L-proline hydrochloride

(-)-trans-5-Methyl-L-proline hydrochloride is a proline derivative[1].

  • CAS Number: 38228-15-8
  • MF: C6H12ClNO2
  • MW: 165.61798
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FOY 251-D4

FOY 251 is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1].

  • CAS Number: 71079-09-9
  • MF: C17H19N3O7S
  • MW: 409.41400
  • Catalog: Metabolic Disease
  • Density: 1.36g/cm3
  • Boiling Point: 592.6ºC at 760 mmHg
  • Melting Point: 194-198ºC
  • Flash Point: 312.2ºC

2-Amino-N-phenylpropanamide hydrochloride

2-Amino-N-phenylpropanamide (Compound 5b) hydrochloride is a Tocainid (HY-B1798) analog. Tocainid is an antiarrythmic agent[1].

  • CAS Number: 153973-14-9
  • MF: C9H13ClN2O
  • MW: 200.67
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Bromoindole

5-Bromoindole is a chemical intermediate that can be used for the synthesis of GSK-3 inhibitors and anti-cancer agents[1][2].

  • CAS Number: 10075-50-0
  • MF: C8H6BrN
  • MW: 196.044
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 316.9±15.0 °C at 760 mmHg
  • Melting Point: 90-92 °C(lit.)
  • Flash Point: 145.5±20.4 °C

Tetrahydropyrimidine-2(1H)-thione-d6

Tetrahydropyrimidine-2(1H)-thione-d6 is the deuterium labeled Tetrahydropyrimidine-2(1H)-thione[1].

  • CAS Number: 1219802-05-7
  • MF: C4H2D6N2S
  • MW: 122.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Diethylamino-2-Oxo-Chromene-3-Carbohydrazide

7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds[1].

  • CAS Number: 100343-98-4
  • MF: C14H17N3O3
  • MW: 275.303
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Nle-OH

Z-Nle-OH is a leucine derivative[1].

  • CAS Number: 39608-30-5
  • MF: C14H19NO4
  • MW: 265.305
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 449.2±38.0 °C at 760 mmHg
  • Melting Point: 56-58ºC
  • Flash Point: 225.5±26.8 °C

Anitrazafen

Anitrazafen is a topically effective antiinflammatory agent.

  • CAS Number: 63119-27-7
  • MF: C18H17N3O2
  • MW: 307.34600
  • Catalog: Inflammation/Immunology
  • Density: 1.164g/cm3
  • Boiling Point: 482.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 172.1ºC

Peptide5

Peptide5 is a connexin43 mimetic peptide. Peptide5 reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Peptide5 exhibits analgesic effects in models of neuropathic pain.

  • CAS Number: 916977-43-0
  • MF: C60H98N16O20S
  • MW: 1395.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PESTAHIVIN

HUN-7293 is a cell adhesion molecule inhibitor. HUN-7293 selectively inhibits the expression of three cell adhesion molecules (VCAM-1, ICAM-1 and E-selectin) (IC50=1-24 nM). HUN-7293 can be used in the study of inflammatory and autoimmune diseases characterized by overexpression of cell adhesion molecules[1].

  • CAS Number: 165754-55-2
  • MF: C53H84N8O9
  • MW: 977.28200
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(E)-(-)-Aspongopusamide B

(E)-(-)-Aspongopusamide B (Compound 9) is a natural product that can be isolated from the insect Aspongopus chinensis[1].

  • CAS Number: 1632326-65-8
  • MF: C20H20N2O6
  • MW: 384.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY FL SSE

BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λex=502 nm, λem=511 nm)[1][2].

  • CAS Number: 217190-17-5
  • MF: C18H17BF2N3NaO7S
  • MW: 491.21
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Paeoniflorin sulfite

Paeoniflorin, a main component of Paeoniae Radix Alba, could be transformed into Paeoniflorin sulfite during sulfur-fumigation of Paeoniae Radix Alba[1].

  • CAS Number: 1146967-98-7
  • MF: C23H28O13S
  • MW: 544.53
  • Catalog: Others
  • Density: 1.76±0.1 g/cm3(Predicted)
  • Boiling Point: 765.5±70.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

calythropsin

Calythropsin is a cytotoxic chalcone, with weak effect on mitosis, and presumably also on tubulin polymerization[1].

  • CAS Number: 152340-67-5
  • MF: C16H14O5
  • MW: 286.28
  • Catalog: Cancer
  • Density: 1.369g/cm3
  • Boiling Point: 555.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 210.4ºC

4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside

Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants[1][2].

  • CAS Number: 229644-17-1
  • MF: C32H48O8S
  • MW: 592.78400
  • Catalog: Neurological Disease
  • Density: 1.186g/cm3
  • Boiling Point: 738.127ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 400.205ºC