N-(2,4-Dinitrophenyl)-L-valine is a valine derivative[1].
KBU2046 is an oral, highly selective inhibitor of cell motility and cell invasion in vitro. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of the hallmarks of classical HSP90 inhibitors. KBU2046 inhibits cancer metastasis and prolongs life[1].
Bromuron-d6 is the deuterium labeled Bromuron[1].
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3[1][2].
Beesioside Q is a oleanolic acid triterpene saponin isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr[1].
Tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, inhibits TNFα-induced apoptosis. Tubuloside B possesses antioxidative effects[1][2].
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (kcat/Km) at pH 7.5 for cleavage is 5.2 M-1 s-1[1].
Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate) is an analogue of Raloxifene 4'-glucuronide.
(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM.
Isothiocyanatobenzene-13C6,15N is the 13C- and 15N-labeled Isothiocyanatobenzene[1].
Leucoside is a natural compound isolated from tea seed extract[1].
PEG300 is a neutral and biocompatible hydrophilic polymer.
Human serum albumin (HSA) is the most abundant protein in plasma, representing the major factor of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory and antiplatelet aggregation activity as well as colloid osmotic effect. Human serum albumin is also associated with cardiovascular diseases, serving as an independent prognosticator[1][2].
Calcein-AM is cell-permeable fluorescent dye used to determine the cell viability.
Rotenolone is an antiproliferative agent. Rotenolone shows antiproliferative activity against the ovarian cancer A2780, breast cancer BT-549, prostate cancer DU 145, NSCLC NCI-H460, and colon cancer HCC-2998 cell lines, with IC50s of 0.95, 1.6, 2.7, 2.0, and 2.9 μM, respectively[1].
PCA50941 is a 1,4-dihydropyridine derivative, used for treatment for cardiovascular disease.
Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides[1][2].
DL-4-Thiaisoleucine is an isoleucine derivative[1].
Pulchinenoside B is a triterpenoid saponin isolated from Pulsatilla chinensis[1].
16:0 Coenzyme A-d4 is deuterium labeled 16:0 Coenzyme A.
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups[1].
Umckalin is a oxygenated coumarin from Pelargonium sidoides[1].
VP-U-6 is a nucleoside analog that can be used in oligonucleotide synthesis[1].
IRAK-4 Peptide substrate (IRAK-1 (360-380)) is a biological active peptide. (This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4)
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1].
L-Glucose-13C-1 is the 13C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake[1][2].
Glycine Zinc Salt Monohydrate [for Protein Research] is a Glycine (HY-Y0966) derivative[1].
Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].
(2S,3R)-Brassinazole, the enantiomer of Brassinazole (BRZ). Brassinazole inhibits brassinosteroid (BR) biosynthesis, via acting on the oxidative processes from 6-oxo-campestanol to teasterone. (2S,3R)-Brassinazole might be the most active form of Brz[1][2][3].
Denthyrsinin is a phenanthrene[1].