Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Simridarlimab

Simridarlimab is a humanized IG antibody targeting CD274/CD47[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16-Epipyromesaconitine

16-Epipyromesaconitine is a natural product that can be obtained by the pyrolysis of Mesaconitine (HY-N0724)[1].

  • CAS Number: 132054-38-7
  • MF: C24H37NO8
  • MW: 467.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

0MPTP hydrochloride

MPTP hydrochloride is a brain penetrant dopamine neurotoxin, inducing Parkinson’s Disease.

  • CAS Number: 23007-85-4
  • MF: C12H16ClN
  • MW: 209.715
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 258.6ºC at 760mmHg
  • Melting Point: 254 - 257 °C
  • Flash Point: 105.8ºC

(2,5-DIMETHYL-PHENYL)-THIOUREA

((2,6-Dichlorophenyl)sulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 19818-06-5
  • MF: C8H7Cl2NO4S
  • MW: 284.11600
  • Catalog: Others
  • Density: 1.622g/cm3
  • Boiling Point: 486.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 248.3ºC

H-Glu-Ser-OH

Glu-Ser is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 5875-38-7
  • MF: C8H14N2O6
  • MW: 234.21
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GENZ-882706

GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor extracted from patent WO 2017015267A1.

  • CAS Number: 2070864-35-4
  • MF: C26H25N5O3
  • MW: 455.51
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BOC-NLE-OHDCHA

Boc-Nle-OH.DCHA is a leucine derivative[1].

  • CAS Number: 21947-32-0
  • MF: C23H44N2O4
  • MW: 412.607
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5(6)-Carboxy-X-rhodamine

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

  • CAS Number: 198978-94-8
  • MF: C33H30N2O5
  • MW: 534.60
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2S,3R,4E)-N-TETRACOSANOYL SPHINGOSINE

C24-Ceramide is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide induces time-dependent changes in membrane properties. C24-Ceramide induces membrane reorganization[1][2].

  • CAS Number: 102917-80-6
  • MF: C42H83NO3
  • MW: 650.11300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Desmethyl Galanthamine

N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].

  • CAS Number: 41303-74-6
  • MF: C16H19NO3
  • MW: 273.32700
  • Catalog: Others
  • Density: 1.309g/cm3
  • Boiling Point: 457.923ºC at 760 mmHg
  • Melting Point: 142-145ºC
  • Flash Point: 230.744ºC

Kansuiphorin C

Kansuiphorin C ameliorates malignant ascites by modulating gut microbiota and related metabolic functions[1].

  • CAS Number: 133898-77-8
  • MF: C29H34O6
  • MW: 478.58
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 606.7±44.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.8±21.9 °C

1-Methoxymethyl-β-carboline

1-Methoxymethyl-β-carboline is a natural product isolated from the root of Eurycoma longifolia[1].

  • CAS Number: 55854-60-9
  • MF: C13H12N2O
  • MW: 212.24700
  • Catalog: Others
  • Density: 1.26g/cm3
  • Boiling Point: 399.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 133.3ºC

5′-Des-O-methylharringtonine

5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia[1].

  • CAS Number: 182325-73-1
  • MF: C27H35NO9
  • MW: 517.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzoyl-Phe-Ala-Arg

Benzoyl-Phe-Ala-Arg is a peptide.

  • CAS Number: 89020-38-2
  • MF: C25H32N6O5
  • MW: 496.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hispidalin

Hispidalin is a novel antimicrobial peptide with broad and efficient antibacterial activity against various bacterial and fungal pathogens, and can be used as an antibacterial agent and food preservative[1].

  • CAS Number: 2243219-67-0
  • MF: C255H378N72O78
  • MW: 5700.17
  • Catalog: Bacterial
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline

(4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline is a proline derivative[1].

  • CAS Number: 489447-09-8
  • MF: C11H20N2O4
  • MW: 244.2875
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 388.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.0±27.9 °C

Ammonium-15N,d4 chloride

Ammonium-15N,d4 (chloride) is the deuterium and 15N labeled Ammonium chloride[1].

  • CAS Number: 99011-95-7
  • MF: ClD4N
  • MW: 57.51610
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 340ºC (subl.)(lit.)
  • Flash Point: N/A

D-Val-Leu-Arg p-nitroanilide diacetate salt

D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin[1].

  • CAS Number: 64816-14-4
  • MF: C23H38N8O5
  • MW: 506.59800
  • Catalog: Others
  • Density: 1.34g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) trifluoroacetate salt

Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) is a biologically active peptide.

  • CAS Number: 1927927-12-5
  • MF: C205H310N58O61S2
  • MW: 4627.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Transferrin aldifitox

Transferrin aldifitox (TF-CRM107) is a diphtheria toxin CRM107 conjugate with transferrin. Transferrin aldifitox can be used to research anticancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Epiagarotetrol

6-Epiagarotetrol is a neuroprotective agent can be extracted from Aquilaria sinensis. 6-Epiagarotetrol has a protective effect on corticosterone-induced PC12 cell damage[1].

  • CAS Number: 2580359-99-3
  • MF: C17H18O6
  • MW: 318.32
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2S)-(+)-1-BENZOYL-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE

Butabindide (UCL-1397) is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide inhibits TPP II to protect CCK-8 against inactivation[1][2].

  • CAS Number: 175553-48-7
  • MF: C19H27N3O6
  • MW: 393.43400
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 741.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 402.1ºC

ETIROXATE

Etiroxate (CG-635) is a lipid lowing compound which can be used for hyperlipoproteinemia research[1].

  • CAS Number: 17365-01-4
  • MF: C18H17I4NO4
  • MW: 818.95
  • Catalog: Metabolic Disease
  • Density: 2.321g/cm3
  • Boiling Point: 563.7ºC at 760 mmHg
  • Melting Point: 149-151ºC
  • Flash Point: 294.7ºC

Dendroaspis Natriuretic Peptide

Dendroaspis Natriuretic Peptide is a vasodilator peptide that can be isolated from animal venom[1].

  • CAS Number: 255721-52-9
  • MF: C180H282N56O56S2
  • MW: 4190.64
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Succinyl-CoA synthetase

Succinyl-CoA synthetase catalyzes the only substrate-level phosphoryl-ation step in the tricarboxylic acid cycle. Succinyl-CoA synthetase is a phosphate target for the activation of mitochondrial metabolism[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-aniline

Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity[1].

  • CAS Number: 769933-15-5
  • MF: C18H26N4O2S
  • MW: 362.490
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 732.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 397.0±32.9 °C

Samalizumab

Samalizumab (ALXN 6000) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ML 239

ML239 is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.

  • CAS Number: 1378872-36-6
  • MF: C13H10Cl3N3O2
  • MW: 346.596
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Janus Green B

Janus green B is a supravital stain. Janus green B staining reaction is oxygen dependent, and is reversibly inhibited by cyanide. Janus green B has been used for staining peripheral nerves in live insects, lymphatic vessels of rabbits and mitochondria[1][2][3].

  • CAS Number: 2869-83-2
  • MF: C30H31ClN6
  • MW: 511.060
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 160 °C (dec.)(lit.)
  • Flash Point: N/A

(2S,4R)-1-(TERT-BUTOXYCARBONYL)-4-(PROP-2-YN-1-YL)PYRROLIDINE-2-CARBOXYLIC ACID

Boc-(R)-4-(2-propynyl)-L-proline is a proline derivative[1].

  • CAS Number: 959581-98-7
  • MF: C13H19NO4
  • MW: 253.29400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A