Monomethyl auristatin E intermediate-14 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
λ-Carrageenan is a seaweed polysaccharide which has been generally used as proinflammatory agent in the basic research. λ-Carrageenan is a potent antitumor agent[1].
Eriodictyol 7-O-glucuronide is a flavonoid isolated from Cosmos sulphureus[1].
Isogambogenic acid is a natural product that can be isolated from Resina Garciniae. Isogambogenic acid has cytotoxicity to cancer cell lines with IC50 values of 0.4327-5.942 μmol/L[1].
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-D-serine is a serine derivative[1].
Cyclamic acid (Cyclohexylsulfamic acid) sodium is one of the most widely used artificial sweetenersin food and pharmaceuticals[1].
(2-Fluoro-4-biphenyl)acetic acid-d5 is the deuterium labeled (2-Fluoro-4-biphenyl)acetic acid[1].
BGN3 is a good substrate for the SNAP-tag® and H5 enzymes. The activities of SNAP-tag® and H5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively)[1].
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3].
Kizuta saponin K11 is a saponin found in the leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant[1].
3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1].
16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver drugs[1].
N-Ethoxycarbonyl-L-phenylalanine is a phenylalanine derivative[1].
2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(4-(trifluoromethyl)phenyl)aceticacid is a Glycine (HY-Y0966) derivative[1].
(Z)-2-Bromo-3-methyl-2-butenedioic acid, one of brominated haloacids, is a disinfection byproduct (DBP) at in finished drinking waters[1].
C3-Amide-C4-NH2 is a potent linker[1].
5-Br-PAPS is a highly specific Zn2+ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn2+ by forming a deeply colored red Zn2+ complex[1].
N-Glutarylglycine is a Glycine (HY-Y0966) derivative[1].
7-Methyl-1-naphthyl acetic acid is a potentinhibitor of auxin action in plants. 7-Methyl-1-naphthyl acetic acid inhibitsAUX1, PIN, and ABCB protein-mediated auxin transport expressed in yeast.7-Methyl-1-naphthyl acetic acid can be used in auxin dependent development[1].
Ethylenediaminetetraacetic acid-d16 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].
Cbz-Pro-Leu-Gly-OH is a tripeptide that can be used in Parkinson's disease research[1].
Boc-D-Arg(Tos)-OH is an arginine derivative[1].
ERDRP-0519 is an orally bioavailable small-molecule polymerase inhibitor.
H-Asp-OH.Mg is an aspartic acid derivative[1].
Hoechst 33342 analog is an anglog of Hoechst 33342, which is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.
Traumatic Acid is a monounsaturated dicarboxylic acid isolated from Phaseolus vulgaris. Traumatic Acid can cause a decrease in membrane phospholipid peroxidation and show antioxidant and stimulatory effects on collagen biosynthesis. Traumatic Acid is a potential agent for the treatment of many skin diseases connected with collagen biosynthesis disorders and oxidative stress[1].
H-D-Ser-OMe.HCl is a serine derivative[1].
G280-9 is a 9 amino acid native epitope peptide. G280-9 is a relevant target expressed on melanoma.
Tegafur-Uracil is an orally active fluoropyrimidines anticancer agent. Tegafur-Uracil inhibits thymidylate synthase. Tegafur-Uracil can be used for researching anti solid tumors[1].
Glucotropaeolin potassium (Benzylglucosinolate potassium) , a glucosinolate contained in cruciferous vegetables, causes a moderate decrease in spontaneous DNA damage in animals[1].