Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

C26 D,L-Carnitine-d9

C26 D,L-Carnitine-d9 is deuterium labeled C26 D,L-Carnitine.

  • CAS Number: 2260670-67-3
  • MF: C33H56D9NO4
  • MW: 548.93
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Lys-OH

Z-Lys-OH is a lysine derivative[1].

  • CAS Number: 2212-75-1
  • MF: C14H20N2O4
  • MW: 280.320
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 497.0±45.0 °C at 760 mmHg
  • Melting Point: 226-231 °C (dec.)(lit.)
  • Flash Point: 254.4±28.7 °C

Fuchsine base monohydrochloride

Fuchsine base (monohydrochloride) is a magenta dye, which is certified for use for acid-fast staining with carbol-fuchsin.

  • CAS Number: 632-99-5
  • MF: C20H20ClN3
  • MW: 337.846
  • Catalog: Dye Reagents
  • Density: 0.999 g/mL at 20 °C
  • Boiling Point: 589.3ºC at 760 mmHg
  • Melting Point: 250 °C
  • Flash Point: 48 °F

WR99210

WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM[1]. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains[2].

  • CAS Number: 47326-86-3
  • MF: C14H18Cl3N5O2
  • MW: 394.68400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

15-Methoxypinusolidic acid

15-Methoxypinusolidic acid (compound 1) is a labdane diterpene compound isolated from the leaves of Calocedrus microlepic[1].

  • CAS Number: 769928-72-5
  • MF: C21H30O5
  • MW: 362.46
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 531.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 182.8±23.6 °C

Ceplignan

Ceplignan ((2S,3R)-Ceplignan) is a neogenic lignan, which can be isolated from the rhizomes of Acorus tatarinowii Schott. (2S,3R)-Ceplignan and (2R,3S)-ceplignan are two isomers of Ceplignan[1].

  • CAS Number: 185244-78-4
  • MF: C18H18O7
  • MW: 346.331
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 540.6±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.4±23.6 °C

Arg-Gly-Asp-Cys TFA

Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding[1].

  • CAS Number: 2171504-22-4
  • MF: C17H28F3N7O9S
  • MW: 563.51
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(Phenylmethyl)pentadecanamide

N-Benzylpentadecanamide is a natural N-benzylamide found in Maca (Lepidium meyenii)[1].

  • CAS Number: 1572037-13-8
  • MF: C22H37NO
  • MW: 331.54
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Fluoro-4-methoxybenzene-d4

1-Fluoro-4-methoxybenzene-d4 is the deuterium labeled 1-Fluoro-4-methoxybenzene[1].

  • CAS Number: 1219802-94-4
  • MF: C7H7FO
  • MW: 126.128
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 157.7±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 43.3±0.0 °C

Rbin-1

Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136±7 nM.

  • CAS Number: 328023-11-6
  • MF: C13H12N4S
  • MW: 256.326
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 479.6±47.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 243.8±29.3 °C

Sterebins A

Sterebin A is a bisnorditerpenoid that can be found in Blumea aromatic[1].

  • CAS Number: 107647-14-3
  • MF: C18H30O4
  • MW: 310.42800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Reparixin Racemate

(Rac)-Reparixin is the inactive isomer of Reparixin (HY-15251), and can be used as an experimental control. Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively.

  • CAS Number: 957407-64-6
  • MF: C14H21NO3S
  • MW: 283.39
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Histone H3K9me3 (1-15)

Histone H3K9me3 (1-15) (H3(1-15)K9me3) is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin. Trimethylation of histone H3 at lysine 9 is associated with gene repression, prevents transcription factor binding[1][2].

  • CAS Number: 951011-30-6
  • MF: C66H124N25O21+
  • MW: 1603.85
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kaempferol 3-O-beta-sophoroside

Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1].

  • CAS Number: 19895-95-5
  • MF: C27H30O16
  • MW: 610.518
  • Catalog: Inflammation/Immunology
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 995.0±65.0 °C at 760 mmHg
  • Melting Point: 194-198℃
  • Flash Point: 329.3±27.8 °C

Caryolane-1,9β-diol

Caryolane-1,9β-diol (Treibs glycol; 3,6-Caryolanediol) is a natural compound isolated from the pods of Sindora sumatrana[1].

  • CAS Number: 155485-76-0
  • MF: C15H26O2
  • MW: 238.366
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 331.7±10.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 148.6±13.6 °C

PNC-27

PNC-27 is an anticancer peptide, containing an HDM-2-binding domain. PNC-27 shows anti-tumor activity and can be used in acute myeloid leukemia research[1][2][3].

  • CAS Number: 1159861-00-3
  • MF: C188H293N53O44S
  • MW: 4031.73
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Warfarin sodium

Warfarin sodium (WARF-42 sodium; Athrombine-K sodium) is a potent anticoagulant agent and a vitamin K1 recycling antagonist to deplete active vitamin K1. Warfarin sodium decreases blood coagulation and prevents blood clot formation by inhibiting vitamin K epoxide reductase[1][2].

  • CAS Number: 129-06-6
  • MF: C19H15NaO4
  • MW: 330.310
  • Catalog: Cardiovascular Disease
  • Density: 1.307g/cm3
  • Boiling Point: 515.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 188.8ºC

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research[1][2].

  • CAS Number: 1815618-06-4
  • MF: C137H217N47O41S4
  • MW: 3306.739
  • Catalog: Cardiovascular Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bornyl acetate

(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings[1][2][3].

  • CAS Number: 20347-65-3
  • MF: C12H20O2
  • MW: 196.286
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 223.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 87.4±6.0 °C

(R)-L888607

(R)-L 888607 is the inactive isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].

  • CAS Number: 2446042-90-4
  • MF: C19H15ClFNO2S
  • MW: 375.84
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Decanoyl-Dl-Homoserine Lactone

N-Decanoyl-DL-homoserine lactone is a serine derivative[1].

  • CAS Number: 106983-36-2
  • MF: C14H25NO3
  • MW: 255.35300
  • Catalog: Others
  • Density: 1.02±0.1 g/cm3
  • Boiling Point: 466.1±34.0 °C
  • Melting Point: N/A
  • Flash Point: N/A

Heteroclitin A

Heteroclitin A is a lignan isolated from the stems of Schisandra propinqua.

  • CAS Number: 140369-75-1
  • MF: C28H36O8
  • MW: 500.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chloroacetyl-dl-valine

N-Chloroacetyl-DL-valine is a valine derivative[1].

  • CAS Number: 4090-17-9
  • MF: C7H12ClNO3
  • MW: 193.62800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 130ºC
  • Flash Point: N/A

L-Theanine

L-Theanine (L-Glutamic Acid γ-ethyl amide)is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

  • CAS Number: 3081-61-6
  • MF: C7H14N2O3
  • MW: 174.198
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 430.2±40.0 °C at 760 mmHg
  • Melting Point: 207°C
  • Flash Point: 214.0±27.3 °C

(2H14)-1,1':3',1''-Terphenyl

1,1':3',1''-Terphenyl-d14 is the deuterium labeled 1,1':3',1''-Terphenyl[1].

  • CAS Number: 17714-84-0
  • MF: C18D14
  • MW: 244.390
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 365.0±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 175.7±13.7 °C

5-FAM-Amyloid β-Protein (1-42) trifluoroacetate salt

β-Amyloid (1-42), human, FAM-labeled is a biological active peptide. (FAM labled HY-P1363)

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-Ile-OH

Arginylisoleucine is a biologically active peptide.

  • CAS Number: 62632-70-6
  • MF: C14H29N5O5
  • MW: 347.41100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Evolitrine

Evolitrine (7-Methoxydictamnine; Evolitrin) is isolated from Acronychia pedunculata and show anti-inflammatory and antifeedant activities[1].

  • CAS Number: 523-66-0
  • MF: C13H11NO3
  • MW: 229.23100
  • Catalog: Inflammation/Immunology
  • Density: 1.261g/cm3
  • Boiling Point: 381ºC at 760mmHg
  • Melting Point: 115℃
  • Flash Point: 184.2ºC

CCK (26-31) (non-sulfated)

CCK (26-31) (non-sulfated) is the N-terminal fragment of CCK, a peptide hormone found in the gut and brain that stimulates digestion, regulates satiety, and is associated with anxiety. CCK (26-31) is also less active in non-sulfated than in sulfated form[1].

  • CAS Number: 89911-64-8
  • MF: C38H50N8O10S2
  • MW: 842.981
  • Catalog: Metabolic Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1110.0±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 625.1±37.1 °C

beta-zearalenol

β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level[1].

  • CAS Number: 71030-11-0
  • MF: C18H24O5
  • MW: 320.38000
  • Catalog: Others
  • Density: 1.174g/cm3
  • Boiling Point: 599ºC at 760 mmHg
  • Melting Point: 137-139ºC
  • Flash Point: 217.9ºC