Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

FMOC-L-Phenylalanine

Fmoc-Phe-OH is a phenylalanine derivative[1].

  • CAS Number: 35661-40-6
  • MF: C24H21NO4
  • MW: 387.428
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 620.1±50.0 °C at 760 mmHg
  • Melting Point: 180-187 °C(lit.)
  • Flash Point: 328.8±30.1 °C

Oxypalmatine

Oxypalmatine is isolated from Phellodendron amurense[1].

  • CAS Number: 19716-59-7
  • MF: C21H21NO5
  • MW: 367.39500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oxazine 1 perchlorate

Oxazine 1 perchlorate is a symmetric cationic dye (λex=653 nm, λem=666 nm).

  • CAS Number: 24796-94-9
  • MF: C20H26ClN3O5
  • MW: 423.89100
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CCCI-01

CCCI-01 is a centrosome clustering inhibitor. CCCI-01 has selective effects on cancer. CCCI-01 can be used for the research of non-cross-resistant anti-cancer agents with blocking centrosome clustering[1].

  • CAS Number: 215778-97-5
  • MF: C11H9N3O4
  • MW: 247.20700
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Protogracillin

Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW). Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action[1].

  • CAS Number: 54848-30-5
  • MF: C51H84O23
  • MW: 1065.199
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DBCO-PEG2-DBCO

DBCO-PEG2-DBCO is a click chemistry reagent containing an azide group. DBCO-PEG2-DBCO is a PEG linker containing two terminal DBCO groups. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. T Reagent grade, for research use only[1].

  • CAS Number: 2639395-48-3
  • MF: C44H42N4O6
  • MW: 722.83
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino(cyclohexyl)acetic acid

Cyclohexylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 5664-29-9
  • MF: C8H15NO2
  • MW: 157.210
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 248.3±23.0 °C at 760 mmHg
  • Melting Point: 256ºC
  • Flash Point: 104.2±18.9 °C

Boc-Val-Val-OH

(tert-Butoxycarbonyl)-L-valyl-L-valine is a valine derivative[1].

  • CAS Number: 69209-73-0
  • MF: C15H28N2O5
  • MW: 316.39300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide

(Rac)-TTA-P2 is the inactive isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease[1].

  • CAS Number: 918430-49-6
  • MF: C21H29Cl2FN2O2
  • MW: 431.37
  • Catalog: Neurological Disease
  • Density: 1.25g/cm3
  • Boiling Point: 510.1°C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 262.3°C

N3-Gly-Aeg(Fmoc)-OH

N3-Gly-Aeg(Fmoc)-OH is a click chemistry reagent containing an azide group. PNA building-block that can be further modified using Click-chemistry[1].

  • CAS Number: 2606227-07-8
  • MF: C21H21N5O5
  • MW: 423.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5(6)-FAM SE

5(6)-FAM SE is an amine-reactive green fluorescent dye widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine.

  • CAS Number: 117548-22-8
  • MF: C25H15NO9
  • MW: 473.39
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 224ºC
  • Flash Point: N/A

Dabsyl chloride

Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

  • CAS Number: 56512-49-3
  • MF: C14H14ClN3O2S
  • MW: 323.79800
  • Catalog: Dye Reagents
  • Density: 1.29 g/cm3
  • Boiling Point: 483.6ºC at 760 mmHg
  • Melting Point: 185 °C (dec.)(lit.)
  • Flash Point: 246.3ºC

2-(2H5)Ethyl(2H12)hexan-1-ol

2-Ethylhexan-1-ol-d17 is the deuterium labeled 2-Ethylhexan-1-ol[1].

  • CAS Number: 202480-75-9
  • MF: C8HD17O
  • MW: 147.333
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 184.6±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 77.2±0.0 °C

4-Azido-1-hydroxy-2,2,6,6-tetramethylpiperidine

N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

  • CAS Number: 63697-61-0
  • MF: C9H18N4O
  • MW: 198.26500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

p-Methylphenyl potassium sulfate

p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin.

  • CAS Number: 91978-69-7
  • MF: C7H7KO4S
  • MW: 226.29100
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

γ-D-Glutamylaminomethylsulfonic acid

γ-D-Glutamylaminomethylsulfonic acid is a glutamic acid derivative[1].

  • CAS Number: 90237-02-8
  • MF: C6H12N2O6S
  • MW: 240.23400
  • Catalog: Others
  • Density: 1.593g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3-Bis[(2H3)methyloxy](2H4)benzene

1,3-Dimethoxybenzene-d10 is the deuterium labeled 1,3-Dimethoxybenzene[1]. 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds[2].

  • CAS Number: 340257-57-0
  • MF: C8D10O2
  • MW: 148.225
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 217.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 87.8±0.0 °C

RRLIEDAEpYAARG

RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)

  • CAS Number: 118447-68-0
  • MF: C64H107N22O24P
  • MW: 1599.64
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

24:0 Coenzyme A-d4

24:0 Coenzyme A-d4 is deuterium labeled 24:0 Coenzyme A.

  • CAS Number: 2260670-66-2
  • MF: C45H87D4N10O17P3S
  • MW: 1173.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

UC-1728 (t-TUCB)

UC-1728 is a potent rabbit soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 2 nM on rabbit liver.

  • CAS Number: 948304-40-3
  • MF: C21H21F3N2O5
  • MW: 438.40
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Leucine,L-threonyl-L-valyl

Thr-Val-Leu is a central nervous system tripeptide[1].

  • CAS Number: 66317-22-4
  • MF: C15H29N3O5
  • MW: 331.40800
  • Catalog: Others
  • Density: 1.158g/cm3
  • Boiling Point: 644.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 343.5ºC

Bismuth Potassium Citrate

Gastrodenol(Bismuth tripotassium dicitrate; De-Noltab)is a mineral that is used in treating ulcers and upset stomach.

  • CAS Number: 57644-54-9
  • MF: C6H8O7.1/2Bi.3/2K
  • MW: 355.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 309.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 155.2ºC

Ac-pSar12-OH

Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC)[1][2].

  • CAS Number: 2313534-24-4
  • MF: C38H64N12O14
  • MW: 912.99
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Licoisoflavanone

Licoisoflavanone is the isoflavonoid compound isolated from Sinkiang licorice root (Glycyrrhiza)[1].

  • CAS Number: 66067-26-3
  • MF: C20H18O6
  • MW: 354.35300
  • Catalog: Others
  • Density: 1.401g/cm3
  • Boiling Point: 551.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199ºC

Glycidyl Palmitate-d5

Glycidyl Palmitate-d5 is the deuterium labeled Glycidyl Palmitate[1].

  • CAS Number: 1794941-80-2
  • MF: C19H36O3
  • MW: 312.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tbid

tBID is a selective inhibitor of homeodomain–interacting protein kinase 2 (HIPK2) with an IC50 of  0.33 µM.

  • CAS Number: 1639895-85-4
  • MF: C11H3Br4N3O2
  • MW: 528.78
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Vitamin E

DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].

  • CAS Number: 10191-41-0
  • MF: C29H50O2
  • MW: 430.706
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 485.9±0.0 °C at 760 mmHg
  • Melting Point: 2-4°C
  • Flash Point: 210.2±24.4 °C

Trihexosylceramide (d18:1/12:0)

Trihexosylceramide (d18:1/12:0) is a type of Trihexosylceramide. In the renal tissue of heterozygous Fabry's disease, the cytoplasm of glomerular epithelial cells appears foamy. Trihexosylceramide accumulated in glomerular epithelial cells as identified by immunostaining[1][2].

  • CAS Number: 474943-80-1
  • MF: C42H79NO13
  • MW: 806.08
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Ser(tBu)-Ser(Psi(Me,Me)pro)-OH

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 1000164-43-1
  • MF: C28H34N2O7
  • MW: 510.579
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 716.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 386.9±32.9 °C

(24S)-20,24-Dihydroxydammar-25-en-3-one

20(S),24(S)-Dihydroxydammar-25-en-3-one (compound 19) is a kind of triterpene. 20(S),24(S)-Dihydroxydammar-25-en-3-one can be isolated from the floral spikes of Betula platyphylla var. 20(S),24(S)-Dihydroxydammar-25-en-3-one has cytotoxicity against Human Cancer Cell Lines[1].

  • CAS Number: 75069-59-9
  • MF: C30H50O3
  • MW: 458.716
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 556.3±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.3±22.4 °C