Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(2S,4R)-1-(TERT-BUTOXYCARBONYL)-4-(4-(TRIFLUOROMETHYL)BENZYL)PYRROLIDINE-2-CARBOXYLIC ACID

Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline is a proline derivative[1].

  • CAS Number: 957311-17-0
  • MF: C18H22F3NO4
  • MW: 373.36700
  • Catalog: Others
  • Density: 1.282g/cm3
  • Boiling Point: 454.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 228.5ºC

Euojaponine D

Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity[1].

  • CAS Number: 128397-42-2
  • MF: C41H47NO17
  • MW: 825.808
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 873.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 481.8±34.3 °C

Trimethylgallic acid

3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

  • CAS Number: 118-41-2
  • MF: C10H12O5
  • MW: 212.199
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 376.3±0.0 °C at 760 mmHg
  • Melting Point: 168-171 °C(lit.)
  • Flash Point: 128.8±20.0 °C

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

  • CAS Number: 2260669-94-9
  • MF: C42D82NO8P
  • MW: 842.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hyponine D

Hyponine D is an immunosuppressive sesquiterpene alkaloid that could be isolated from Tripterygium wilfordii[1].

  • CAS Number: 259823-31-9
  • MF: C47H50N2O18
  • MW: 930.903
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 929.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 515.9±34.3 °C

4''-O-Glucosyl-17α-deacetyltanghinin

17β-Tanghinigenin is a kind of glucos-3-ulosyl-thevetoside[1].

  • CAS Number: 114612-75-8
  • MF: C36H54O14
  • MW: 710.814
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Duocarmycin SA intermediate-1

Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation[1].

  • CAS Number: 919535-07-2
  • MF: C30H35IN2O8
  • MW: 678.51200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gadodiamide

Gadodiamide(Omniscan) is a gadolinium-based MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.

  • CAS Number: 131410-48-5
  • MF: C16H26GdN5O8
  • MW: 573.656
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 769.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 419ºC

Fructo-oligosaccharideDP13/GF12

Fructo-oligosaccharide DP13 is an Inulin (HY-N7075)-type fructo-oligosaccharide that can be isolated from Morinda Officinalis[1].

  • CAS Number: 137405-37-9
  • MF: C78H132O66
  • MW: 2125.84
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bacoside A3

Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity[1].

  • CAS Number: 157408-08-7
  • MF: C47H76O18
  • MW: 929.09600
  • Catalog: Neurological Disease
  • Density: 1.43
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Aminopyrene-1,3,6-trisulfonic Acid

8-Aminopyrene-1,3,6-trisulfonic acid trisodium is a water-soluble anionic fluorescent dye. The fluorescence intensity of 8-Aminopyrene-1,3,6-trisulfonic acid trisodium remains nearly constant over a pH range from 4 to 10[1].

  • CAS Number: 196504-57-1
  • MF: C16H8NNa3O9S3
  • MW: 523.400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: ≥250ºC(lit.)
  • Flash Point: N/A

N6-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxyadenosine

N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate.

  • CAS Number: 64325-78-6
  • MF: C38H35N5O6
  • MW: 657.71400
  • Catalog: Others
  • Density: 1.32 g/cm3
  • Boiling Point: N/A
  • Melting Point: 94 °C
  • Flash Point: N/A

Crystal Ponceau 6R

Crystal Ponceau 6R is a red azo dye. Crystal Ponceau 6R used in histology, for staining fibrin with the martius, scarlet and blue (MSB) Trichrome stain[1].

  • CAS Number: 2766-77-0
  • MF: C20H12N2Na2O7S2
  • MW: 502.42800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC(lit.)
  • Flash Point: N/A

Kallikrein 5-IN-2

Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching[1].

  • CAS Number: 2361160-57-6
  • MF: C23H22N6O
  • MW: 398.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Regaloside C

Regaloside C is a glycerol glucoside isolated from the bulbs of Lilium genus with anti-inflammatory activities. Regaloside C has cardiomyocyte protective activity by protecting the mitochondria in H2O2-induced heart H9C2 cells[1].

  • CAS Number: 117591-85-2
  • MF: C18H24O11
  • MW: 416.37700
  • Catalog: Cardiovascular Disease
  • Density: 1.59±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HD-Chg-OH HCl

H-D-Chg-OH.HCl is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 61367-40-6
  • MF: C8H16ClNO2
  • MW: 193.67100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 322.7ºC at 760 mmHg
  • Melting Point: >220ºC
  • Flash Point: 149ºC

Anti-inflammatory agent 32

Anti-inflammatory agent 32 (compound C3) has anti-oxidative and anti-inflammatory activity. Anti-inflammatory agent 32 can be used for skin care products research and development[1].

  • CAS Number: 2577388-38-4
  • MF: C20H20O4
  • MW: 324.37
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SynuClean-D

SynuClean-D (SC-D) is an inhibitor of α-synuclein aggregation, disrupts mature amyloid fibrils, prevents fibril propagation, and abolishes the degeneration of dopaminergic neurons in an animal model of Parkinson’s disease[1].

  • CAS Number: 685121-45-3
  • MF: C13H5F3N4O5
  • MW: 354.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TMRM

TMRM is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).

  • CAS Number: 115532-49-5
  • MF: C25H25N2O3
  • MW: 401.48
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

O-tert-Butyl-L-serine methylester hydrochloride

H-Ser(tBu)-OMe.HCl is a serine derivative[1].

  • CAS Number: 17114-97-5
  • MF: C8H18ClNO3
  • MW: 211.686
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 240.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 80.3ºC

DL-Lysine Dihydrochloride

DL-Lysine (dihydrochloride) is a lysine derivative[1].

  • CAS Number: 617-68-5
  • MF: C6H16Cl2N2O2
  • MW: 219.109
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 311.5ºC at 760 mmHg
  • Melting Point: 190-195ºC (dec.)
  • Flash Point: 142.2ºC

L-Cystine N-carboxyanhydride

L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery[1].

  • CAS Number: 51507-96-1
  • MF: C8H8N2O6S2
  • MW: 292.28900
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RXFP1 receptor agonist-4

RXFP1 receptor agonist-4 (Example 268) is a RXFP1 receptor agonist. RXFP1 receptor agonist-4 inhibits cAMP production in HEK293 cells stably expressing human RXFP1, with an EC50 value of 4.9 nM[1].

  • CAS Number: 2941376-76-5
  • MF: C32H24F7N3O5S
  • MW: 695.60
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N,N-Trimethyl(2H33)hexadecan-1-aminium bromide

Cetrimonium-d33 (bromide) is the deuterium labeled Cetrimonium bromide[1]. Cetrimonium bromide (CTAB) is an amine based cationic quaternary surfactant, is one of the components of the topical antiseptic Cetrimide.

  • CAS Number: 347841-42-3
  • MF: C19H9BrD33N
  • MW: 397.651
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

17alpha-Thevebioside

17α-Thevebioside is the compound isolated from air-dried leaves of Cerbera manghas and C. odollam[1].

  • CAS Number: 114613-59-1
  • MF: C36H56O13
  • MW: 696.82
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 856.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 263.4±27.8 °C

2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid

α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities[1].

  • CAS Number: 490-20-0
  • MF: C18H16O4
  • MW: 296.317
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 470.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 252.4±25.2 °C

β-S-ARCA

β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines[1].

  • CAS Number: 1093268-63-3
  • MF: C22H31N10O17P3S
  • MW: 832.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Bromo-4-chlorobutane-d8

1-Bromo-4-chlorobutane-d8 is the deuterium labeled 1-Bromo-4-chlorobutane[1].

  • CAS Number: 1219803-72-1
  • MF: C4H8BrCl
  • MW: 171.463
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 164.3±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 60.0±0.0 °C

Methyl blue

Methyl blue belongs to the group of triaminotriphenylmethane dyes. Methyl blue is widely used as antiseptic dye in polychrome staining method and has applications in histological and microbiological staining solutions. Methyl blue has been used as a model to study the effect of various catalysts on photodegradation of dyes[1][2].

  • CAS Number: 28983-56-4
  • MF: C37H27N3Na2O9S3
  • MW: 799.799
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Tellimoside) is a flavonol glycoside with strong inhibitory activity against the growth of Microcystis aeruginosa[1].

  • CAS Number: 56316-75-7
  • MF: C28H24O16
  • MW: 616.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A