Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2,3-Diaminophenazine

2,3-Diaminophenazine (2,3-Phenazinediamine) is an amino derivative of phenazine with promising luminescence, electrochemical and biochemical applications[1][2].

  • CAS Number: 655-86-7
  • MF: C12H10N4
  • MW: 210.235
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 497.8±15.0 °C at 760 mmHg
  • Melting Point: >300ºC
  • Flash Point: 287.1±7.6 °C

N-Methyl-L-leucine

N-Methyl-DL-leucine is a leucine derivative[1].

  • CAS Number: 2566-33-8
  • MF: C7H15NO2
  • MW: 145.199
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 226.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 90.6±22.6 °C

1,1':2',1''-Terphenyl-d14

1,1':2',1''-Terphenyl-d14 is the deuterium labeled 1,1':2',1''-Terphenyl[1].

  • CAS Number: 5142-67-6
  • MF: C18D14
  • MW: 244.39000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Iodoacetamide

2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[1][2].

  • CAS Number: 144-48-9
  • MF: C2H4INO
  • MW: 184.964
  • Catalog: Others
  • Density: 2.3±0.1 g/cm3
  • Boiling Point: 297.1±23.0 °C at 760 mmHg
  • Melting Point: 92-95 °C(lit.)
  • Flash Point: 133.5±22.6 °C

Fmoc-Tyr(3-F,tBu)-OH

Fmoc-Tyr(3-F,tBu)-OH is a cyclic peptide compound with high membrane permeability and can specifically binds to a target molecule (extracted from patent WO2018225864A1)[1].

  • CAS Number: 2254698-84-3
  • MF: C28H28FNO5
  • MW: 477.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bempedoic acid impurity 1-d4

Bempedoic acid impurity 1-d4 is the deuterium labeled Bempedoic acid impurity 1[1].

  • CAS Number: 2408132-01-2
  • MF: C19H30D4O5
  • MW: 346.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cadralazine

Cadralazine (ISF 2469) is an orally active antihypertensive agent. Cadralazine is a peripheral arteriolar vasodilator[1].

  • CAS Number: 64241-34-5
  • MF: C12H21N5O3
  • MW: 283.32700
  • Catalog: Cardiovascular Disease
  • Density: 1.253 g/cm3
  • Boiling Point: 425.88°C (rough estimate)
  • Melting Point: 160-162°
  • Flash Point: N/A

HD-Ser(tBu)-OH

H-D-SER(TBU)-OH is a serine derivative[1].

  • CAS Number: 18783-53-4
  • MF: C7H15NO3
  • MW: 161.199
  • Catalog: Others
  • Density: 1.08 g/cm3
  • Boiling Point: 266.0±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 114.6±24.6 °C

foresaconitine

Foresaconitine(Vilmorrianine C) is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli.

  • CAS Number: 73870-35-6
  • MF: C35H49NO9
  • MW: 627.765
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 663.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.0±31.5 °C

N3-1,4-trans-CHC-OH

N3-1,4-trans-CHC-OH is a click chemistry reagent containing an azide group.

  • CAS Number: 1931895-14-5
  • MF: C7H11N3O2
  • MW: 169.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase[1][2].

  • CAS Number: 206443-06-3
  • MF: C16H17NaO11S
  • MW: 440.35400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 196-198?C
  • Flash Point: N/A

Linalyl acetate

Linalyl acetate is the principal components of many plant essential oils with potentially anti-inflammatory activity[1].

  • CAS Number: 115-95-7
  • MF: C12H20O2
  • MW: 196.286
  • Catalog: Inflammation/Immunology
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 220.0±0.0 °C at 760 mmHg
  • Melting Point: 85°C
  • Flash Point: 90.0±0.0 °C

(R)-4-Carboxyphenylglycine

(R)-4CPG ((R)-4-Carboxyphenylglycine) is a less avtive R-enantiomer of (S)-4CPG[1].

  • CAS Number: 134052-68-9
  • MF: C9H9NO4
  • MW: 195.17200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aurothioglucose

Aurothioglucose (Gold thioglucose) is a well known active-site inhibitor of TrxR1, inhibited TrxR1 activity in HeLa cell cytosol but had no effect on the viability of the cells.IC50 value:Target: TrxR1in vitro: Trx1 redox state and ROS generation were measured in cells exposed to the TrxR1 inhibitors aurothioglucose (ATG) and monomethylarsonous acid (MMA(III)) and in cells depleted of TrxR1 activity by siRNA knock down [1].in vivo: Adult mice received a single intratracheal dose of 0.375 μg/g lipopolysaccharide (LPS) 12 h before a single intraperitoneal injection of 25 mg/kg ATG. Control mice received intratracheal and/or intraperitoneal saline. ATG treatment significantly attenuated lung injury, increased lung GCLM expression and GSH levels, and decreased mortality. GSH depletion completely prevented the protective effects of ATG in LPS/hyperoxia-exposed mice [2].

  • CAS Number: 12192-57-3
  • MF: C6H11AuO5S
  • MW: 392.18000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Demethylcephalotaxinone

Demethylcephalotaxinone is an alkaloid. Demethylcephalotaxinone can be isolated from Hainan cycad (C. hainanensis)[1].

  • CAS Number: 51020-45-2
  • MF: C17H17NO4
  • MW: 299.32
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 517.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 267.0±30.1 °C

1-Aminohydantoin hydrochloride

1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection[1].

  • CAS Number: 2827-56-7
  • MF: C3H6ClN3O2
  • MW: 151.552
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 256.8ºC at 760 mmHg
  • Melting Point: 201-205 °C(lit.)
  • Flash Point: 109.1ºC

Efpegsomatropin

Efpegsomatropin is an active peptide. Efpegsomatropin can be used for various biochemical studies.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Udonitrectag

Udonitrectag (REC 0559), a low molecular weight compound that mimics NGF, aims to address the issue of NGF stability[1].

  • CAS Number: 1458063-04-1
  • MF: C20H19NO5
  • MW: 353.37
  • Catalog: Neurological Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 611.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323.9±31.5 °C

FD-1080 free acid

FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging[1].

  • CAS Number: 1151888-25-3
  • MF: C40H39ClN2O6S2
  • MW: 743.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-2-Thiolhistidine

D-2-Thiolhistidine can be used for modification of proteins and peptides.

  • CAS Number: 1195264-93-7
  • MF: C6H9N3O2S
  • MW: 187.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fluzinamide

Fluzinamide is an effective antiepileptic.

  • CAS Number: 76263-13-3
  • MF: C12H13F3N2O2
  • MW: 274.23900
  • Catalog: Neurological Disease
  • Density: 1.337g/cm3
  • Boiling Point: 415.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.2ºC

HAMNO

HAMNO is a novel protein interaction inhibitor of replication protein A (RPA).

  • CAS Number: 138736-73-9
  • MF: C17H13NO2
  • MW: 263.29100
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucidenic acid E

Lucidenic acid E is a terpenoid from Ganoderma lucidum[1].

  • CAS Number: 98665-17-9
  • MF: C29H40O8
  • MW: 516.62300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium tetradecyl sulfate

Sodium tetradecyl sulfate (Tergitol 4) is a sclerosing agent used for the research of varicose veins[1][2].

  • CAS Number: 139-88-8
  • MF: C14H29NaO4S
  • MW: 316.43200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pppApG

pppApG is a starting product of both vRNA (viral RNA) and cRNA (complementary RNA) synthesis. pppApG can be used for influenza virus research[1].

  • CAS Number: 68892-47-7
  • MF: C20H28N10O20P4
  • MW: 852.39
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

C16:1 Ceramide-d7

C16:1 Ceramide-d7 is deuterium labeled C16:1 Ceramide.

  • CAS Number: 1942907-49-4
  • MF: C34H58D7NO3
  • MW: 542.93
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methacetin-methoxy-13C

Methacetin-methoxy-13C is the 13C labeled Methacetin-methoxy[1].

  • CAS Number: 72156-70-8
  • MF: C9H11NO2
  • MW: 166.18200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 128-130ºC(lit.)
  • Flash Point: N/A

Rhaponticin 2''-O-gallate

Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production[1].

  • CAS Number: 94356-24-8
  • MF: C28H28O13
  • MW: 572.51
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SQDG

SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations[1].

  • CAS Number: 123036-44-2
  • MF: C43H76O12S
  • MW: 817.12
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

γ-2-MSH (41-58), amide

γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands[1].

  • CAS Number: 799841-81-9
  • MF: C74H100N22O15S
  • MW: 1569.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A