Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

N-Acetylglycyl-D-glutamic acid

N-Acetylglycyl-D-glutamic acid is a peptide with excitatory effect. N-Acetylglycyl-D-glutamic acid induces seizures in mice[1].

  • CAS Number: 135701-69-8
  • MF: C9H14N2O6
  • MW: 246.21700
  • Catalog: Neurological Disease
  • Density: 1.378g/cm3
  • Boiling Point: 666.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 356.8ºC

Butyrospermol

Butyrospermol is a natural product[1].

  • CAS Number: 472-28-6
  • MF: C30H50O
  • MW: 426.71700
  • Catalog: Others
  • Density: 0.986g/cm3
  • Boiling Point: 498.303°C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 220.984°C

3-Azidopropanoic acid-PFP ester

3-Azidopropanoic acid-PFP ester is an azidopropanoic acid linker that contains an activated PFP ester. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to form triazole linkages. The activated PFP ester can react with amine groups to form stable amide bonds[1].

  • CAS Number: 1240801-10-8
  • MF: C9H4F5N3O2
  • MW: 281.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Span 80

Sorbitan monooleate is a renewable polyol with unique molecular structures for the development and design of bio-based waterborne polyurethane (WPU) with versatility and excellent mechanical properties. Sorbitan monooleate can be used as an excipient, such as nonionic surfactants, emulsifiers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 1338-43-8
  • MF: C24H44O6
  • MW: 428.603
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 579.3±50.0 °C at 760 mmHg
  • Melting Point: 0.986ºC
  • Flash Point: 186.2±23.6 °C

Boc-3-(2-quinolyl)-DL-Ala-OH

Boc-3-(2-quinolyl)-DL-Ala-OH is an alanine derivative[1].

  • CAS Number: 401813-49-8
  • MF: C17H20N2O4
  • MW: 316.352
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 505.6±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 259.6±28.7 °C

bromfenac sodium salt sesquihydrate

Bromfenac (sodium hydrate) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity(1) Bromfenac (sodium hydrate) (1 mg/kg, i.v.) is metabolited into an unusual conjugate, bromfenac N-glucoside, in rats bile(2) Bromfenac (sodium hydrate) permeation was found to be 1.62-fold higher through ChS-CS-NPs

  • CAS Number: 120638-55-3
  • MF: C15H12BrNO3.3/2H2O.Na
  • MW: 383.17
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 562.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 293.8±30.1 °C

dl-valine ethyl ester hydrochloride

H-DL-Val-OEt.HCl is a valine derivative[1].

  • CAS Number: 23358-42-1
  • MF: C7H16ClNO2
  • MW: 181.660
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 169.2ºC at 760mmHg
  • Melting Point: 94ºC
  • Flash Point: 42.7ºC

MeIQ

Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].

  • CAS Number: 77094-11-2
  • MF: C12H12N4
  • MW: 212.25000
  • Catalog: Cancer
  • Density: 1.36g/cm3
  • Boiling Point: 465.7ºC at 760 mmHg
  • Melting Point: 291-293ºC
  • Flash Point: 235.4ºC

L-Alanine 4-methoxy-β-naphthylamide hydrochloride

H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M[1].

  • CAS Number: 3438-14-0
  • MF: C14H17ClN2O2
  • MW: 280.75000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Deacetylorientalide

Deacetylorientalide (compound 19) is a germacrane-type sesquiterpenoid compound that can be found in from Sigesbeckia orientalis[1].

  • CAS Number: 1258517-59-7
  • MF: C19H22O7
  • MW: 362.374
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BDC2.5 mimotope 1040-31

BDC2.5 mimotope 1040-31 is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells[1][2].

  • CAS Number: 329696-49-3
  • MF: C63H97N17O14S
  • MW: 1348.61
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Notoginsenoside Fa

Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain[1][2].

  • CAS Number: 88100-04-3
  • MF: C59H100O27
  • MW: 1241.41000
  • Catalog: Neurological Disease
  • Density: 1.48±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoflavone

Isoflavone, a soy phytoestrogen and a biologically active component, presents in several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa[1][2].

  • CAS Number: 574-12-9
  • MF: C15H10O2
  • MW: 222.239
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 367.0±42.0 °C at 760 mmHg
  • Melting Point: 150ºC
  • Flash Point: 171.1±21.4 °C

3-epi-Katonic acid

Epikatonic acid (compound 4) is a triterpene. Epikatonic acid can be isolated from Eriope latifolia and Eriope blanchetii[1].

  • CAS Number: 76035-62-6
  • MF: C30H48O3
  • MW: 456.700
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 552.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 302.1±26.6 °C

NAV 2729

NAV-2729 is a dual Arf1/Arf6 activation inhibitor.

  • CAS Number: 419547-11-8
  • MF: C25H17ClN4O3
  • MW: 456.88
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Castanospermine

Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).target:α- and β-glucosidases.IC 50: 1.2 uM [2] in vitro :Castanospermine, [(1 S,6S,7R,8R,8aR)-1 ,6,7,8-tetrahydroxyoctahydroindolizine]is a potent and specific inhibitor of mammalian and plant α-and β-D-glucosidases in vitro [1] in vivo: Experiments in vivo with castanospermine, an inhibitor of the glucosidases that convert protein N-linked high mannose carbohydrates to complex oligosaccharides, resulted in significant inhibition of tumor growth in nude mice.[3]

  • CAS Number: 79831-76-8
  • MF: C8H15NO4
  • MW: 189.209
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 421.9±45.0 °C at 760 mmHg
  • Melting Point: 213-217 °C(lit.)
  • Flash Point: 267.6±27.4 °C

Sephadex G150

Sephadex G 150 is a hydrophilic gel that can be used as a gel filter filler (Particle size range: 40-120 μm; Sphere protein separation range: 5k-300k Da)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DSPE-Thiol

DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers[1].

  • CAS Number: 144735-82-0
  • MF: C44H86NO9PS
  • MW: 836.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Resorufin acetate

Resorufin acetate is a fluorescent dye that selectively detects hydrazine[1].

  • CAS Number: 1152-14-3
  • MF: C14H9NO4
  • MW: 255.22600
  • Catalog: Others
  • Density: 1.38g/cm3
  • Boiling Point: 408.2ºC at 760mmHg
  • Melting Point: 223ºC(lit.)
  • Flash Point: 197.9ºC

(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one

(-)-Altenuene is a heptaketide isolated from an endolichenic fungal strain Nigrospora sphaerica[1].

  • CAS Number: 889101-41-1
  • MF: C15H16O6
  • MW: 292.284
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 609.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 233.5±25.0 °C

1α-Hydroxytorilin

1 α-hydroxytorilin (compound 3) is a sesquiterpenoid. 1 α-hydroxytorilin can be isolated from Torilis japonica. 1α-hydroxytorilin has cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells with ED50 values of 20.52, 18.24, 17.48, 42.54 μg/mL, respectively[1].

  • CAS Number: 887147-75-3
  • MF: C22H32O6
  • MW: 392.486
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 502.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.3±23.6 °C

BLXA-4

BLXA-4 is used potentially to treat gingival diseases.

  • CAS Number: 362516-29-8
  • MF: C23H34O5
  • MW: 390.51
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bz-Tyr-4-Abz-OH

Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function[1].

  • CAS Number: 37106-97-1
  • MF: C23H20N2O5
  • MW: 404.41500
  • Catalog: Others
  • Density: 1.367g/cm3
  • Boiling Point: 797.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 435.9ºC

Atrial Natriuretic Peptide (7-28), human, canine

Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag[1].

  • CAS Number: 128746-58-7
  • MF: C100H155N33O30S3
  • MW: 2395.70
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cimicifugoside H1

Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss[1][2][3].

  • CAS Number: 163046-73-9
  • MF: C37H54O11
  • MW: 674.81800
  • Catalog: Metabolic Disease
  • Density: 1.31±0.1 g/cm3 at 760 mmHg
  • Boiling Point: 748.9±60.0 °C at 760 mmHg
  • Melting Point: 260-262 °C
  • Flash Point: N/A

12-Hydroxyganoderic acid D

12-Hydroxyganoderic Acid D is a triterpenoid extracted from Ganoderma lucidum[1].

  • CAS Number: 942950-96-1
  • MF: C30H42O8
  • MW: 530.650
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 722.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 404.6±29.4 °C

Retronecine

Retronecine ((+)-Retronecine) is a pyrrolizidine alkaloid found in a variety of plants. Retronecine is the most common central core for other pyrrolizidine alkaloids[1].

  • CAS Number: 480-85-3
  • MF: C8H13NO2
  • MW: 155.19400
  • Catalog: Others
  • Density: 1.29g/cm3
  • Boiling Point: 291.3ºC at 760mmHg
  • Melting Point: 119-120°
  • Flash Point: 161.4ºC

Microsomal aminopeptidase

Microsomal aminopeptidase (microsomal aminoptidase) was first reported from C. elegans. The Microsomal aminopeptidase is beneficial for the development of molecular vaccines against parasitic nematodes[1].

  • CAS Number: 9054-63-1
  • MF: C12H24O2
  • MW: 200.31776
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Benzimidazolethiol-d4

2-Benzimidazolethiol-d4 is the deuterium labeled 2-Benzimidazolethiol[1].

  • CAS Number: 931581-17-8
  • MF: C7H2D4N2S
  • MW: 154.22600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Gulose

L-Gulose, the putative furanose form of L-sorbosone, is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vitamin C)[1].

  • CAS Number: 6027-89-0
  • MF: C6H12O6
  • MW: 180.156
  • Catalog: Metabolic Disease
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 410.8±45.0 °C at 760 mmHg
  • Melting Point: 132ºC
  • Flash Point: 202.2±28.7 °C