Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

L-Ascorbyl 6-palmitate

Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C, it is also used as an antioxidant food additive.

  • CAS Number: 137-66-6
  • MF: C22H38O7
  • MW: 414.533
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 512.7±50.0 °C at 760 mmHg
  • Melting Point: 115-118 °C(lit.)
  • Flash Point: 164.4±23.6 °C

Methyl 3-(2,4-dihydroxyphenyl)propanoate

Methyl-3-(2,4-dihydroxy phenyl) propanoate is a phenylpropanoic ester with antifeedant activity[1].

  • CAS Number: 17422-90-1
  • MF: C10H12O4
  • MW: 196.200
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 348.7±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 138.3±12.8 °C

Cedrelopsin

Cedrelopsin is a natural phenylpropanoid compound[1].

  • CAS Number: 19397-28-5
  • MF: C15H16O4
  • MW: 260.285
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 457.6±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 172.7±22.2 °C

Cyanine3.5

Cyanine3.5 free unactivated monofunctional carboxylic acid. Can be used as a reference non-reactive dye or control. Cyanine3.5 is an analog of Cy3.5? fluorophore.

  • CAS Number: 1802928-88-6
  • MF: C38H41ClN2O2
  • MW: 593.21
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

OT-R antagonist 1

OT-R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 1 inhibits oxytocin-evoked intracellular Ca2+ mobilization (IC50 = 8 nM).IC50 value: 8 nMTarget: oxytocin receptorin vitro: OT-R antagonist 1 inhibitis IP3-Synthesis, rat OT-R (IC50=0.03 uM). [4] OT-R antagonist 1 inhibits phosphodiesterase IV with IC50 = 6.1 μM, a value about 300-fold higher than the affinity for OT-R. OT-R antagonist 1 shows a very clean selectivity profile with specific interaction with OT-R. OT-R antagonist 1 competitively inhibits binding of [3H]oxytocin and the peptide antagonist 125I-ornithine vasotocin analog to human and rat oxytocin receptor expressed in human embryonic kidney 293-EBNA or Chinese hamster ovary cells with nanomolar potency. Selectivity against vasopressin receptor subtypes is >6-fold for V1a and >350-fold for V2 and V1b. [1]in vivo: Oxytocininduced contraction of isolated rat uterine strips is blocked by OT-R antagonist 1 (pA2 = 7.82). In anesthetized nonpregnant rats, single administration of OT-R antagonist 1 by i.v. or oral routes causes dose-dependent inhibition of contractions elicited by repeated injections of oxytocin with ED50 = 3.5 mg/kg i.v. and 89 mg/kg p.o., respectively. OT-R antagonist 1 significantly inhibits spontaneous uterine contractions in pregnant rats near term when administered intravenously or orally. [1]

  • CAS Number: 364071-17-0
  • MF: C28H29N3O4
  • MW: 471.548
  • Catalog: Oxytocin Receptor
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Glucose,2-(benzoylamino)-2-deoxy

N-Benzoyl-D-glucosamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 655-42-5
  • MF: C13H17NO6
  • MW: 283.27700
  • Catalog: Others
  • Density: 1.408 g/cm3
  • Boiling Point: 682.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 366.5ºC

5-Carboxyfluorescein Diacetate

5-CFDA(5-Carboxyfluorescein diacetate) is membrane-permeant and can be loaded into cells via incubation; hydrolyzed by intracellular esterases to 5-carboxyfluorescein; used for labeling human intervertebral disk cells in vitro for fluorescence microscopy.

  • CAS Number: 79955-27-4
  • MF: C25H16O9
  • MW: 460.389
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 693.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 241.9±25.0 °C

terphenyl-d14

1,1':4',1''-Terphenyl-d14 is the deuterium labeled 1,1':4',1''-Terphenyl[1].

  • CAS Number: 1718-51-0
  • MF: C18D14
  • MW: 244.390
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 400.0±12.0 °C at 760 mmHg
  • Melting Point: 212-213ºC(lit.)
  • Flash Point: 188.1±13.7 °C

Azido-PEG2-CH2COOH (CHA)

Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent[1].

  • CAS Number: 2098500-94-6
  • MF: C12H24N4O4
  • MW: 288.34336
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 74 °C
  • Flash Point: N/A

Boc-D-Phg-OH

(αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]benzeneacetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 33125-05-2
  • MF: C13H17NO4
  • MW: 251.278
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 382.6±25.0 °C at 760 mmHg
  • Melting Point: 88-91 °C
  • Flash Point: 185.2±23.2 °C

CART (61-102) (human, rat) trifluoroacetate salt

CART (61-102) (rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 209615-75-8
  • MF: C189H316N58O56S7
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jaconine

Jaconine is a natural product that can be isolated from honey of the Ragwort (Senecio jacobaea)[1].

  • CAS Number: 480-75-1
  • MF: C18H26ClNO6
  • MW: 387.85500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Chloro-3’-deoxy-3’-fluoroadenosine

2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 122654-30-2
  • MF: C10H11ClFN5O3
  • MW: 303.68
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 550.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.4±32.9 °C

(S)-Licoisoflavone A

(S)-Licoisoflavone A (Dihydrolicoisoflavone) is an isoflavanone that can be isolated from swartzia polyphylla[1].

  • CAS Number: 164163-92-2
  • MF: C20H20O6
  • MW: 356.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nidufexor

Nidufexor is a farnesoid X receptor (FXR) agonist[1].

  • CAS Number: 1773489-72-7
  • MF: C27H22ClN3O4
  • MW: 487.93
  • Catalog: FXR
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 781.1±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 426.2±32.9 °C

Diphenylterazine

Diphenylterazine is a bioluminescence agent.

  • CAS Number: 344940-63-2
  • MF: C25H19N3O
  • MW: 377.44
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

butane-1,4-diaminium dichloride

1,4-Diaminobutane dihydrochloride is an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI) [1]. 1,4-Diaminobutane dihydrochloride is an important source of GABA[2].

  • CAS Number: 333-93-7
  • MF: C4H14Cl2N2
  • MW: 161.073
  • Catalog: Others
  • Density: 1.472g/cm3
  • Boiling Point: 159ºC at 760 mmHg
  • Melting Point: 280 °C (dec.)(lit.)
  • Flash Point: 51.7ºC

(5β,8α,10α)-Kaura-9(11),16-dien-18-oic acid

Grandiflorenic acid is a natural producr that can be found in Espeleth schultzii Wedd.[1].

  • CAS Number: 22338-67-6
  • MF: C20H28O2
  • MW: 300.44
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 447.5±44.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 209.7±23.1 °C

Galactose oxidase

Galactose oxidase (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide[1].

  • CAS Number: 9028-79-9
  • MF: C7H13NO3
  • MW: 159.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dimethyl trisulfide-d6

Dimethyl trisulfide-d6 is deuterium labeled Dimethyl trisulfide (HY-128454). Dimethyl trisulfide is a cyanide antidote[1][2].

  • CAS Number: 58069-93-5
  • MF: C2D6S3
  • MW: 132.30100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2(1H)-Pyrimidinone,4-amino-1-methyl

1-Methylcytosine is a methylated form of the DNA base cytosine and used as a nucleobase of hachimoji DNA, in which it pairs with Isoguanine[1][2].

  • CAS Number: 1122-47-0
  • MF: C5H7N3O
  • MW: 125.12900
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.34g/cm3
  • Boiling Point: 241.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 99.9ºC

vanicoside A

Vanicoside A is a protein kinase C(PKC) inhibitor from Polygonum pensylvanicum[1].

  • CAS Number: 155179-22-9
  • MF: C51H50O21
  • MW: 998.930
  • Catalog: PKC
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1155.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 332.6±27.8 °C

Bz-Tyr-pNA

N-Benzoyl-L-tyrosine p-nitroanilide is a chymotrypsin substrate[1].

  • CAS Number: 6154-45-6
  • MF: C22H19N3O5
  • MW: 405.40
  • Catalog: Ser/Thr Protease
  • Density: 1.373 g/cm3
  • Boiling Point: 776.8ºC at 760 mmHg
  • Melting Point: 235-237 °C
  • Flash Point: 423.6ºC

Tin(II) palmitate

Tin(II) palmitate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 35104-88-2
  • MF: C32H62O4Sn
  • MW: 629.53300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 340.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 154.1ºC

Aminocaproic Nitrilotriacetic Acid

Aminocaproic Nitrilotriacetic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 1043881-31-7
  • MF: C16H29N3O7
  • MW: 375.41700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

O4I1

O4I1 is as a potent Oct3/4 inducer.Target: Oct3/4O4I1 enhances Oct3/4 gene expression, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation. O4I1 activates Oct3/4 at the transcriptional and translational levels in diverse human cell lines. O4I1 promotes Oct3/4 expression in untransfected HEK293 cells quantified by qRT-PCR after 72 h of treatment. O4I1 is sufficient to enhance Oct3/4 overexpression 2-fold and 3-fold after 48 and 72 h of treatment, respectively.

  • CAS Number: 175135-47-4
  • MF: C16H15NO2
  • MW: 253.296
  • Catalog: Oct3/4
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 424.5±30.0 °C at 760 mmHg
  • Melting Point: 140ºC
  • Flash Point: 154.8±17.8 °C

Ohchinin

Ohchinin is a limonoid, that can be isolated from the fruit of Melia azedarach L.[1].

  • CAS Number: 67023-80-7
  • MF: C36H42O8
  • MW: 602.71
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 692.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 372.7±31.5 °C

Loroglossin

Loroglossin (compound 5) is a succinate derivative. Loroglossin can isolated from dried rhizomes of Gymnadenia conopsea[1].

  • CAS Number: 58139-22-3
  • MF: C34H46O18
  • MW: 742.72
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 947.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 292.7±27.8 °C

Bisindolylmaleimide X HCl

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent protein kinase C (PKC) inhibitor[1].

  • CAS Number: 145317-11-9
  • MF: C26H25ClN4O2
  • MW: 460.955
  • Catalog: PKC
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Acetyl-L-isoleucine

(2S,3S)-2-Acetamido-3-methylpentanoic acid is an isoleucine derivative[1].

  • CAS Number: 3077-46-1
  • MF: C8H15NO3
  • MW: 173.210
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 369.6±25.0 °C at 760 mmHg
  • Melting Point: 147-154ºC
  • Flash Point: 177.4±23.2 °C