Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Boc-D-Asp(OcHex)-OH

Boc-D-Asp(OcHex)-OH is an aspartic acid derivative[1].

  • CAS Number: 112898-18-7
  • MF: C15H25NO6
  • MW: 315.36200
  • Catalog: Others
  • Density: 1.18g/cm3
  • Boiling Point: 487.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 248.4ºC

2,4-D sodium salt

2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D sodium salt acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D sodium salt inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].

  • CAS Number: 2702-72-9
  • MF: C8H5Cl2NaO3
  • MW: 243.019
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: 345.6ºC at 760 mmHg
  • Melting Point: 215°C
  • Flash Point: 162.8ºC

Ethyl 2,6-diaminohexanoate dihydrochloride

L-Lysine ethyl ester dihydrochloride is a lysine derivative[1].

  • CAS Number: 3844-53-9
  • MF: C8H20Cl2N2O2
  • MW: 247.163
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 261.9ºC at 760 mmHg
  • Melting Point: ~150 °C (dec.)
  • Flash Point: 97.3ºC

4’-Methyladenosine

4’-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 152540-76-6
  • MF: C11H15N5O4
  • MW: 281.27
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 643.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 342.9±34.3 °C

NHS-NH-(diethylamino)ethyl benzoate

NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling[1].

  • CAS Number: 2050902-45-7
  • MF: C18H23N3O6
  • MW: 377.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beclomethasone 21-Propionate

Benalaxyl-d5is the deuterium labeledBenalaxyl(HY-121109)[1]. Benalaxyl is a fungicide, but A. fumigatus isolates are intrinsically resistant to Benalaxyl[2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-β-D-HomoAla-OH

Z-β-D-HomoAla-OH is an alanine derivative[1].

  • CAS Number: 67843-72-5
  • MF: C12H15NO4
  • MW: 237.25200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 435.6±38.0°C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Surinamine

(S)-3-(4-Hydroxyphenyl)-2-(methylamino)propanoic acid is a tyrosine derivative[1].

  • CAS Number: 537-49-5
  • MF: C10H13NO3
  • MW: 195.215
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 378.8±32.0 °C at 760 mmHg
  • Melting Point: 253-256ºC (dec.)
  • Flash Point: 182.9±25.1 °C

Vat Yellow 2

C.I. Vat Yellow 2 is an agent of yellow dye and can also be used for the paper dyeing[1].

  • CAS Number: 129-09-9
  • MF: C28H14N2O2S2
  • MW: 474.55300
  • Catalog: Others
  • Density: 1.467 g/cm3
  • Boiling Point: 727.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 393.6ºC

Exaluren

Exaluren (ELX-02) is an synthetic eukaryotic ribosome-selective glycoside that induces read through of nonsense mutations, resulting in normally localized full-length functional proteins. Exaluren is used for the research of cystic fibrosis caused by nonsense mutations[1].

  • CAS Number: 1375073-93-0
  • MF: C19H38N4O10
  • MW: 482.53
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 761.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 414.2±32.9 °C

NSC 131114

S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase[1][2].

  • CAS Number: 24425-56-7
  • MF: C16H29N3O6S
  • MW: 391.48300
  • Catalog: Others
  • Density: 1.254g/cm3
  • Boiling Point: 748.5ºC at 760 mmHg
  • Melting Point: 200-202ºC(lit.)
  • Flash Point: 406.5ºC

4-Fluoro(2H4)benzonitrile

4-Fluorobenzonitrile-d4 is the deuterium labeled 4-Fluorobenzonitrile[1].

  • CAS Number: 1080497-29-5
  • MF: C7D4FN
  • MW: 125.136
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 189.6±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 65.6±0.0 °C

Fmoc-D-4-Iodophenylalanine

Fmoc-D-Phe(4-I)-OH is a phenylalanine derivative[1].

  • CAS Number: 205526-29-0
  • MF: C24H20INO4
  • MW: 513.324
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 658.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 352.2±31.5 °C

ammonium sulphate

Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology[1].

  • CAS Number: 7783-20-2
  • MF: H8N2O4S
  • MW: 132.139
  • Catalog: Others
  • Density: 1.76
  • Boiling Point: 330ºC at 760 mmHg
  • Melting Point: 280ºC
  • Flash Point: 26 °C

Olivil monoacetate

Olivil monoacetate is found in Gymnosporia varialilis Loes[1].

  • CAS Number: 1016974-78-9
  • MF: C22H26O8
  • MW: 418.44
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 612.6±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.3±25.0 °C

Fmoc-Val-Gly-OH

Fmoc-Val-Gly-OH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 142810-19-3
  • MF: C22H24N2O5
  • MW: 396.43600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum containing a benzoyl and a cinnamoyl group[1].

  • CAS Number: 268541-27-1
  • MF: C31H36O7
  • MW: 520.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Maoecrystal B

Maoecrystal B is a diterpenoids compound isolated from the leaves of Isodon eriocalyx var. laxiflora[1].

  • CAS Number: 96850-29-2
  • MF: C22H28O6
  • MW: 388.454
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 534.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 184.6±23.6 °C

(25R)-Spirost-4-ene-3,6,12-trione

(25R)-Spirost-4-ene-3,6,12-trione is a natural product, that can be isolated from T. terrestris L[1].

  • CAS Number: 214681-62-6
  • MF: C27H36O5
  • MW: 440.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino(3-thienyl)acetic acid

2-Amino-2-(thiophen-3-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 38150-49-1
  • MF: C6H7NO2S
  • MW: 157.190
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 317.5±32.0 °C at 760 mmHg
  • Melting Point: 238℃
  • Flash Point: 145.8±25.1 °C

Dihydromicromelin B

Dihydromicromelin B is a natural product that can be isolated from the leaves of Micromelum integerrimum[1].

  • CAS Number: 94285-06-0
  • MF: C15H14O6
  • MW: 290.27
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 503.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.4±23.6 °C

Benzyl alcohol-13C6

Benzyl alcohol-13C6 is the 13C labeled Benzyl alcohol[1].

  • CAS Number: 201740-95-6
  • MF: C7H8O
  • MW: 114.09400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(s)-3-(tritylamino)-2-oxetanone

N-Trityl-L-serine lactone is a serine derivative[1].

  • CAS Number: 88109-06-2
  • MF: C22H19NO2
  • MW: 329.39200
  • Catalog: Others
  • Density: 1.22 g/cm3
  • Boiling Point: 489.5ºCat 760 mmHg
  • Melting Point: 191-196ºC (dec.)
  • Flash Point: 249.8ºC

Protopine

Protopine, an isoquinoline alkaloid contained in plants in northeast Asia.IC50 Value:Target:In vitro: Protopine was found to reduce nitric oxide (NO), cyclooxygenase-2 (COX-2), and prostaglandin E(2) (PGE(2)) production by LPS-stimulated Raw 264.7 cells, without a cytotoxic effect. Pre-treatment of Raw 264.7 cells with protopine reduced the production of pro-inflammatory cytokines [2]. Protopine is a novel microtubule stabilizer with anticancer activity in HRPC cells through apoptotic pathway by modulating Cdk1 activity and Bcl-2 family of proteins [3]. In HepG2 cells, protopine significantly increased CYP1A1 mRNA levels after 24h exposure at concentrations from 25 and 10 μM. Protopine also dose-dependently increased CYP1A1 and CYP1A2 mRNA levels in human hepatocytes [4].In vivo: Assays were performed on MDA-MB-231 human breast cancer cells, and the result showed that protopine exhibited anti-adhesive and anti-invasion effects in MDA-MB-231 cells; after treatment with protopine for 90 min, the expression of EGFR, ICAM-1, αv-integrin, β1-integrin and β5-integrin were remarkably reduced [1].

  • CAS Number: 130-86-9
  • MF: C20H19NO5
  • MW: 353.369
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 547.5±49.0 °C at 760 mmHg
  • Melting Point: 211ºC
  • Flash Point: 284.9±29.8 °C

Fmoc-Ile-OH

Fmoc-Ile-OH is an isoleucine derivative[1].

  • CAS Number: 71989-23-6
  • MF: C21H23NO4
  • MW: 353.412
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 559.8±33.0 °C at 760 mmHg
  • Melting Point: 145-147 °C(lit.)
  • Flash Point: 292.4±25.4 °C

3,4-Dichlorophenylalanine

H-Phe(3,4-DiCl)-OH is a phenylalanine derivative[1].

  • CAS Number: 52794-99-7
  • MF: C9H9Cl2NO2
  • MW: 234.079
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 370.6±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.9±27.9 °C

5,6,7,40-tetrahydroxyisoflavone-6,7-di-O-β-D-glucopyranoside

5,​6,​7,​40-​Tetrahydroxyisoflavo​ne-​6,​7-​di-​o-​b-​D-​glucopyranoside is an isoflavonoid glycoside isolated from Pueraria lobata[1].

  • CAS Number: 1219001-04-3
  • MF: C27H30O16
  • MW: 610.518
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 994.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 329.2±27.8 °C

Timtraxanib

Timtraxanib (AVI-3207) is a selective VEGF-2 inhibitor. Timtraxanib can be used for the research of senile macular degeneration[1].

  • CAS Number: 2412172-33-7
  • MF: C28H43N7O9
  • MW: 621.68
  • Catalog: VEGFR
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

XYLOTRIOSE

Xylotriose is a natural xylooligosaccharide, acts as a bifidogenic factor[1].

  • CAS Number: 47592-59-6
  • MF: C15H26O13
  • MW: 414.35900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyanine5 amine hydrochloride

Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A