Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1,1'-Diethyl-2,2'-carbocyanine iodide

Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization[1].

  • CAS Number: 605-91-4
  • MF: C25H25IN2
  • MW: 480.384
  • Catalog: Others
  • Density: 1.151g/cm3
  • Boiling Point: 527.7ºC at 760 mmHg
  • Melting Point: 295 °C (dec.)(lit.)
  • Flash Point: 240.2ºC

Ac-Nle-Pro-Nle-Asp-AMC

Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3].

  • CAS Number: 355140-49-7
  • MF: C33H45N5O9
  • MW: 655.739
  • Catalog: Proteasome
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 902.2±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 499.4±37.1 °C

Z-Gly-Pro-Arg-4MβNA acetate salt

Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). Free 4MβNA can be captured by 5-nitrosalicylaldehyde to produce an insoluble yellow fluorescent and marks the site of thrombin activity[1].

  • CAS Number: 66647-41-4
  • MF: C32H39N7O6
  • MW: 617.70
  • Catalog: Thrombin
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-324572

WAY-324572 is an active molecule.

  • CAS Number: 219988-92-8
  • MF: C20H21FN2O
  • MW: 324.4
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 495.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 253.3±28.7 °C

Bimatoprost

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.Target: Prostaglandin ReceptorBimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue.Bimatoprost activates prostamide alpha F2 receptors found in the hair follicle to stimulate its growth rate. Research led by Professor Randall and the University of Bradford found that it may also offer a treatment for scalp hair regrowth in trials conducted on samples taken from men undergoing hair transplants. According to Allergan's package labeling, users of its Latisse cosmetic product didn't develop darker irises in clinical studies; however, "patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent."

  • CAS Number: 155206-00-1
  • MF: C25H37NO4
  • MW: 415.566
  • Catalog: Prostaglandin Receptor
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 629.8±55.0 °C at 760 mmHg
  • Melting Point: 66-68°C
  • Flash Point: 334.7±31.5 °C

Activated A Subunit

Activated A Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

  • CAS Number: 1155373-30-0
  • MF: C38H37ClN7O4P
  • MW: 722.17
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SYBR Green II (Ionic form)

SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm[1].

  • CAS Number: 178919-00-1
  • MF: C28H28N3OS+
  • MW: 454.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bispyribac sodium

Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor[1].

  • CAS Number: 125401-92-5
  • MF: C19H17N4NaO8
  • MW: 452.350
  • Catalog: Others
  • Density: 1.379 g/cm3
  • Boiling Point: 686.4ºC at 760 mmHg
  • Melting Point: 223-224°C
  • Flash Point: 368.9ºC

2,3-Dihydroxy-3-(4-hydroxyphenyl)propanoic acid

3-Hydroxy-3-(4-hydroxyphenyl)-lactic acid is a key metabolite in the P. roqueforti fermentation approach, with quantitative data of 10.2 ± 1.1 µM in Tyr1 (presence of L-tyrosine) of [1].

  • CAS Number: 100201-57-8
  • MF: C9H10O5
  • MW: 198.17
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 489.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.1±25.2 °C

Trx-red

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

  • CAS Number: 2368978-96-3
  • MF: C29H32ClN3O12S2
  • MW: 714.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

l-valine-2-d1

L-Valine-d1 is the deuterium labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].

  • CAS Number: 77257-03-5
  • MF: C5H10DNO2
  • MW: 118.15300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

boc-(s)-alpha-benzyl-proline

Boc-(S)-α-benzyl-Pro-OH is a proline derivative[1].

  • CAS Number: 706806-61-3
  • MF: C17H23NO4
  • MW: 305.36900
  • Catalog: Others
  • Density: 1.193g/cm3
  • Boiling Point: 443.1ºC at 760 mmHg
  • Melting Point: 146℃
  • Flash Point: 221.8ºC

Vibozilimod

Vibozilimod (example 33) is a S1p1 receptor agonist (extracted from patent WO2012140020A1)[1].

  • CAS Number: 1403232-33-6
  • MF: C29H36ClN3O5
  • MW: 542.07
  • Catalog: LPL Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Glu-OtBu

Boc-Glu-OtBu is a glutamic acid derivative[1].

  • CAS Number: 24277-39-2
  • MF: C14H25NO6
  • MW: 303.351
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 449.8±40.0 °C at 760 mmHg
  • Melting Point: 113 °C
  • Flash Point: 225.8±27.3 °C

sodium hydrogen N-(1-oxooctadecyl)-L-glutamate

Stearoyl glutamic acid sodium (Sodium stearoyl glutamate) is a anionic emulsifier, that can be used as the ingredient of cosmetic. Stearoyl glutamic acid sodium is also an anionic surfactant and an amino acid alkyl amide sensitizer, that may cause allergic contact dermatitis[1][2][3].

  • CAS Number: 38517-23-6
  • MF: C23H41NNaO5
  • MW: 434.56500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 600.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 316.8ºC

7-Methyl-6-thioguanosine

MESG is a chromophoric substrate which can be used for the quantitation of inorganic phosphate.

  • CAS Number: 55727-10-1
  • MF: C11H15N5O4S
  • MW: 313.333
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >175ºC (dec.)
  • Flash Point: N/A

H-Trp-Met-OH

H-Trp-Met-OH is a biologically active peptide.

  • CAS Number: 21438-63-1
  • MF: C16H21N3O3S
  • MW: 335.42100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kaempferol-3-O-(2''-O-beta-D-glucopyl)-beta-D-rutinoside

Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside is a natural glycoside that could be found in Camellia oleifera seeds[1].

  • CAS Number: 55696-58-7
  • MF: C33H40O20
  • MW: 756.65900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Histone H3 (1-20) trifluoroacetate salt

Histone H3 (1-20) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 380598-30-1
  • MF: C91H167N35O27
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2,3,7-tetramethoxyxanthone

1,2,3,7-Tetramethoxyxanthone is a xanthone isolated from Polygala tenuifolia[1].

  • CAS Number: 22804-52-0
  • MF: C17H16O6
  • MW: 316.30500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxy-1-tetralone

5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples[1].

  • CAS Number: 28315-93-7
  • MF: C10H10O2
  • MW: 162.185
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 325.3±31.0 °C at 760 mmHg
  • Melting Point: 206-209 °C(lit.)
  • Flash Point: 138.1±17.4 °C

Lactiflorin

Lactiflorin, a monoterpene glycoside from paeony root, possesses nephroprotective effect[1].

  • CAS Number: 1361049-59-3
  • MF: C23H26O10
  • MW: 462.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-O-benzyl-D-threonine

Boc-D-Thr(Bzl)-OH is a threonine derivative[1].

  • CAS Number: 69355-99-3
  • MF: C16H23NO5
  • MW: 309.358
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 461.5±45.0 °C at 760 mmHg
  • Melting Point: 110-117ºC
  • Flash Point: 232.9±28.7 °C

Benzenepentacarboxylic Acid

Benzenepentacarboxylic acid (BA), a novel fluorescent probeas to detect and scavenge HO-.A specific and reproducible fluorescent probe of HO- developed is utilized to prove and detect the generation of HO- in H2O2/TAED and H2O2/TBCC alkali systems.

  • CAS Number: 1585-40-6
  • MF: C11H6O10
  • MW: 298.15900
  • Catalog: Dye Reagents
  • Density: 1.96g/cm3
  • Boiling Point: 642.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 356.3ºC

(S)-3-hydroxy-2-(2,4,6-triisopropylphenylsulfonamido)propanoic acid

((2,4,6-Triisopropylphenyl)sulfonyl)-L-serine is a serine derivative[1].

  • CAS Number: 159155-05-2
  • MF: C18H29NO5S
  • MW: 371.492
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 512.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.0±32.9 °C

3,5-Dichlorophenol-d3

3,5-Dichlorophenol-d3 is the deuterium labeled 3,5-Dichlorophenol[1].

  • CAS Number: 124286-06-2
  • MF: C6HCl2D3O
  • MW: 166.02000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoserine

3-Amino-2-hydroxypropanoic acid is a serine derivative[1].

  • CAS Number: 565-71-9
  • MF: C3H7NO3
  • MW: 105.093
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 386.6±27.0 °C at 760 mmHg
  • Melting Point: 235ºC (dec.)
  • Flash Point: 187.6±23.7 °C

Pyrromethene 556

Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.

  • CAS Number: 121461-69-6
  • MF: C14H15BF2N2Na2O6S2
  • MW: 466.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucifer Yellow CH dipotassium salt

Lucifer Yellow CH dipotassium is a highly fluorescent dye. Lucifer Yellow CH dipotassium can be viewed both in living tissue and after fixation and embedding. Lucifer Yellow CH dipotassium can be used for marking cells. Lucifer Yellow CH dipotassium spreads rapidly throughout an injected cell. Lucifer Yellow CH dipotassium has a great intrinsic tendency to spread from cell to cell (Ex/Em=430/540 nm)[1][2].

  • CAS Number: 71206-95-6
  • MF: C13H9K2N5O9S2
  • MW: 521.56500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

palustrol

Palustrol is a natural sesquiterpenoid compound[1].

  • CAS Number: 5986-49-2
  • MF: C15H26O
  • MW: 222.37
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 293.7±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 123.0±10.9 °C