Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Methyl N-benzylserinate

Methyl 2-(benzylamino)-3-hydroxypropanoate is a serine derivative[1].

  • CAS Number: 144001-42-3
  • MF: C11H15NO3
  • MW: 209.242
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 351.1±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.2±25.1 °C

Fmoc-D-phe(4-OCH3)-OH

Fmoc-D-Tyr(Me)-OH is a phenylalanine derivative[1].

  • CAS Number: 201335-88-8
  • MF: C25H23NO5
  • MW: 417.454
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 647.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 345.6±31.5 °C

1-Hexen-6-ol

5-Hexen-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 821-41-0
  • MF: C6H12O
  • MW: 100.159
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 149.9±19.0 °C at 760 mmHg
  • Melting Point: <-20ºC
  • Flash Point: 47.2±0.0 °C

Arjunetin

Arjunetin, isolated from Terminalia arjuna, is an insect feeding-deterrent and growth inhibitor[1].

  • CAS Number: 31297-79-7
  • MF: C36H58O10
  • MW: 650.84000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY FL-X

BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λex=504 nm, λem=510 nm)[1][2].

  • CAS Number: 217190-07-3
  • MF: C20H26BF2N3O3
  • MW: 405.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thymidine-5'-triphosphate trisodium salt

Deoxythymidine-5'-triphosphate (dTTP) trisodium salt is one of the four natural deoxynucleotides. Deoxythymidine-5'-triphosphate trisodium salt is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and reverse transcriptase[1].

  • CAS Number: 27821-54-1
  • MF: C10H14N2Na3O14P3
  • MW: 548.114
  • Catalog: DNA/RNA Synthesis
  • Density: 1.922g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S-Ethyl glutathione

S-Ethylglutathione is a biochemical[1].

  • CAS Number: 24425-52-3
  • MF: C12H21N3O6S
  • MW: 335.37700
  • Catalog: Others
  • Density: 1.362g/cm3
  • Boiling Point: 757.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 411.8ºC

H-Ser-Asp-OH

H-Ser-Asp-OH is a biologically active peptide.

  • CAS Number: 2543-31-9
  • MF: C7H12N2O6
  • MW: 220.18000
  • Catalog: Aurora Kinase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-Met-OH acetate salt

Arginylmethionine is a dipeptide composed of arginine and methionine.

  • CAS Number: 45243-23-0
  • MF: C11H23N5O3S
  • MW: 305.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Nitrosodipropylamine-d14

N-Nitrosodipropylamine-d14 is the deuterium labeled N-Nitrosodipropylamine[1].

  • CAS Number: 93951-96-3
  • MF: C6D14N2O
  • MW: 144.27400
  • Catalog: Others
  • Density: 1.013 g/mL at 25ºC(lit.)
  • Boiling Point: 206ºC(lit.)
  • Melting Point: N/A
  • Flash Point: 265ºC

Tos-Gly-Pro-Arg-ANBA-IPA acetate

Tos-Gly-Pro-Arg-ANBA-IPA (acetate) is a peptide substrate for luminescence measurement. Sequence: Tos-Gly-Pro-Arg-ANBA-IPA.

  • CAS Number: 2070009-46-8
  • MF: C32H45N9O10S
  • MW: 747.82
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl (S)-1-Cbz-4-oxo-2-pyrrolidinecarboxylate

(S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate is a proline derivative[1].

  • CAS Number: 16217-15-5
  • MF: C14H15NO5
  • MW: 277.273
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 422.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 209.0±28.7 °C

H-Gly-Lys-Gly-OH

H-Gly-Lys-Gly-OH is a tripeptide containing glycine and lysine. H-Gly-Lys-Gly-OH can be used for the synthesis of casein and soybean protein[1].

  • CAS Number: 45214-22-0
  • MF: C10H20N4O4
  • MW: 260.29000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Farrerol 7-O-β-D-glucopyranoside

Farrerol 7-O-β-D-glucopyranoside (Farrerol 7-O-glucoside) is a flavonoid compound isolated from the leaves of Rhododendron dauricum L[1].

  • CAS Number: 885044-12-2
  • MF: C23H26O10
  • MW: 462.447
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 803.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 279.0±27.8 °C

1-Phenyl(2H3)ethanone

Acetophenone-d3 is the deuterium labeled Acetophenone[1]. Acetophenone is an organic compound with simple structure[2].

  • CAS Number: 17537-31-4
  • MF: C8H5D3O
  • MW: 123.167
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 202.0±0.0 °C at 760 mmHg
  • Melting Point: 19-20ºC(lit.)
  • Flash Point: 82.2±0.0 °C

2′-O-2-Propyn-1-ylguanosine

2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

  • CAS Number: 206552-86-5
  • MF: C13H15N5O5
  • MW: 321.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 737.5±70.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 399.8±35.7 °C

Ethyl nonadecanoate

Ethyl Nonadecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 18281-04-4
  • MF: C21H42O2
  • MW: 326.557
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 359.1±5.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.4±7.5 °C

PF 06424439

PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM[1]. PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate[2].

  • CAS Number: 1469284-79-4
  • MF: C23H30ClN7O4S
  • MW: 536.05
  • Catalog: Acyltransferase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(16R)-Dihydrositsirikine

(16R)-Dihydrositsirikine (19,20-Dihydroisositsirikine) is a natural alkaloid compound[1].

  • CAS Number: 6519-26-2
  • MF: C21H28N2O3
  • MW: 356.46
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 547.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 284.9±28.7 °C

HKSOX-1m

HKSOX-1m is a O2•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells[1].

  • CAS Number: 1802684-30-5
  • MF: C49H37Cl2F10N2O10PS2
  • MW: 1169.82
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WST-8

WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay.

  • CAS Number: 193149-74-5
  • MF: C20H14N6NaO11S2
  • MW: 601.48
  • Catalog: Biochemical Assay Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[(2R)-2,3-di(hexadecanoyloxy)propyl] [1,1,2,2-tetradeuterio-2-(trimethylazaniumyl)ethyl] phosphate

DPPC-d4 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in m

  • CAS Number: 326495-33-4
  • MF: C40H76D4NO8P
  • MW: 738.06400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diethyl phosphate

Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos.

  • CAS Number: 598-02-7
  • MF: C4H11O4P
  • MW: 154.102
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 200.3±23.0 °C at 760 mmHg
  • Melting Point: 6ºC
  • Flash Point: 74.9±22.6 °C

WSP-1

WSP-1 is a selective and rapid-reaction H2S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H2S with the releasing of fluorophore[1].

  • CAS Number: 1352750-34-5
  • MF: C33H21NO6S2
  • MW: 591.653
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 769.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 419.4±32.9 °C

NS-1643

NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM).IC50 value:Target: HERG activatorin vitro: NS1643 enhanced the magnitude of wild-type hERG current in a concentration- and voltage-dependent manner with an EC(50) of 10.4 microM at -10 mV. The fully activated current-voltage relationship revealed that the drug increased outward but not inward currents, consistent with altered inactivation gating. NS1643 shifted the voltage dependence of inactivation by +21 mV at 10 microM and +35 mV at 30 microM, but it did not alter the voltage dependence of activation of hERG channels [1]. In Xenopus laevis oocytes, NS1643 increased both steady-state and tail current at all voltages tested. The EC(50) value for HERG channel activation was 10.5 microM [2]. NS1643 also activates the ERG2 channel; however, the molecular mechanism of the activation differs between the ERG1 and ERG2 channels. For ERG2, NS1643 causes a left-ward shift of the activation curve, a faster time-constant of activation and a slower time-constant of inactivation as well as an increased relative importance for the fast component of deactivation to the total deactivation. In contrast, for ERG1, NS1643 causes a right-ward shift in the voltage-dependent release from inactivation but does not affect time-constants of deactivation [3].

  • CAS Number: 448895-37-2
  • MF: C15H10F6N2O3
  • MW: 380.24200
  • Catalog: Autophagy
  • Density: 1.627g/cm3
  • Boiling Point: 342.311ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.824ºC

3-Methyl-4-hydroxybenzoic acid

4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.

  • CAS Number: 499-76-3
  • MF: C8H8O3
  • MW: 152.147
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 331.3±30.0 °C at 760 mmHg
  • Melting Point: 173-177 °C
  • Flash Point: 168.4±21.1 °C

Luteolin-7-O-alpha-L-arabinopyranosyl (1->6)-beta-D-glucopyranoside

Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside is a flavonoid with antiradical activity[1].

  • CAS Number: 52714-82-6
  • MF: C26H28O15
  • MW: 580.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2(3H)-Furanone,3-aminodihydro-, hydrobromide (1:1)

3-Aminooxolan-2-one hydrobromide is a serine derivative[1].

  • CAS Number: 6305-38-0
  • MF: C4H8BrNO2
  • MW: 182.01600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 257.1ºC at 760 mmHg
  • Melting Point: 220-225 °C(lit.)
  • Flash Point: 120.1ºC

GLPG-3221

GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM. GLPG-3221 can be uesd for the treatment of cystic fibrosis[1].

  • CAS Number: 2222264-64-2
  • MF: C30H37F3N2O6
  • MW: 578.62
  • Catalog: CFTR
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hoechst 33342 trihydrochloride

Hoechst 33342 trihydrochloride is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.

  • CAS Number: 875756-97-1
  • MF: C27H31Cl3N6O
  • MW: 561.93400
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A