Guaiacol Carbonate acts as an expectorant by virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centres and thenperipherally again to the respiratory tract[1].
DLin-KC2-DMA is a cationic/ionizable lipid for siRNA delivery[1].
Protein kinase inhibitor 6 is a protein kinase inhibitor.
FITC-hyodeoxycholic acid is a hyodeoxycholic acid labeled with FITC, which can be used to study the mechanism of action of hyodeoxycholic acid[1].
Epipregnanolone is an endogenous neurosteroid that has anesthetic, hypnotic, and sedative properties.
HDAOS is a novel Trinder's reagent, which is a highly water-soluble aniline derivative; are widely used in diagnostic tests and biochemical tests.
Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia[1].
Chlorahololide D is a potent and selective Potassium Channel blocker with an IC50 value of 2.7 µM. Chlorahololide D is a nature product that could be isolated from the whole plant of Chloranthus holostegius[1].
Haloxyfop-methyl is a high-efficacy herbicide. Haloxyfop-methyl selectively controls several annual and perennial grasses in soybeans and other dicotyledenous crops[1].
TRH-AMC is a fluorogenic substrate used in a coupled assay for thyrotropin-releasing hormone(TRH)-degrading ectoenzyme[1].
H-alpha-Prg-D-Ala-OH is a click chemistry reagent containing an azide group[1].
Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.
Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
(±)-trans-Abscisic acid ((±)-trans-ABA) is an acid. (±)-trans-Abscisic acid can be isolated from strawberry tree (Arbutus unedo L.) honeys[1].
JF646, Tetrazine, a red fluorescent dye, is supplied with a tetrazine reactive handle for copper-free click chemistry. JF646, Tetrazine is suitable for confocal fluorescent imaging, super-resolution microscopy (SRM) techniques such as dSTORM (live and fixed cells) and STED imaging. JF646, Tetrazine is also suitable for flow cytometry.
Isorhynchophylline (IRN), an alkaloid isolated from Uncaria rhynchophylla, possesses the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage.IC50 value:Target:In vitro: Isorhynchophylline concentration-dependently inhibited the platelet-derived growth factor (PDGF)-BB-induced proliferation of PASMCs. Fluorescence-activated cell-sorting analysis showed that isorhynchophylline caused G0/G1 phase cell cycle arrest [2]. Isorhynchophylline can significantly attenuate the cardiomyocyte hypertrophy induced by AngⅡ [3].In vivo: Isorhynchophylline significantly improved spatial learning and memory function in the D-gal-treated mice. Isorhynchophylline significantly increased the level of glutathione (GSH) and the activities of superoxide dismutase (SOD) and catalase (CAT), while decreased the level of malondialdehyde (MDA) in the brain tissues of the D-gal-treated mice [1]. Isorhynchophylline prevented monocrotaline induced pulmonary arterial hypertension in rats, as assessed by right ventricular (RV) pressure, the weight ratio of RV to (left ventricular+septum) and RV hypertrophy. Isorhynchophylline significantly attenuated the percentage of fully muscularized small arterioles, the medial wall thickness, and the expression of smooth muscle α-actin (α-SMA) and proliferating cell nuclear antigen (PCNA) [2].
Palovarotene is a nuclear retinoic acid receptor γ (RAR-γ) agonist.
Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-A can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-A catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline[1].
Apigenin6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside is a natural flavanone compound.
Rubriflorin B is a lignan that can be isolated from Schisandra rubriflora[1].
Vinaginsenoside R4, isolated from the leaves of hydroponic Panax ginseng. It has an inhibitory effect on melanin biosynthesis without any cytotoxic effects on the melan-a cells, and enhances the depigmentation on the zebrafish[1].
The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid which reacts with hydrogen peroxide and 4-aminophenazone to produce a quinone-imine dye with a greater molar absorptivity than that produced with phenol.
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative[1].
5-Methoxytracheloside is a lignan lactone isolated from the stems and leaves of Trachelospermum jasminoides[1].
1-O-Propyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Quinovic acid 3-O-β-D-quinovopyranoside is a tritenpenoid glycoside, that can be isolated from the bark of L. hexandra[1].
(E)-12-hydroxyoctadec-9-enoic acid, sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
DMT-dG(ib) Phosphoramidite-13C10,15N5 is the 13C and 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
D-Arg-[Hyp3,Thi5,8,D-Phe7]-Bradykinin is a biological active peptide. (inhibited bradykinin-induced contractions concentration dependently; bradykinin B2 receptor antagonist)